Torin 1
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- $28 - $4500
- Product name: Torin 1
- CAS: 1222998-36-8
- MF: C35H28F3N5O2
- MW: 607.62
- EINECS:
- MDL Number:MFCD18782653
- Synonyms:1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one;1-[4-(4-PROPANOYLPIPERAZIN-1-YL)-3-(TRIFLUOROMETHYL)PHENYL]-9-QUINOLIN-3-YLBENZO[H][1,6]NAPHTHYRIDIN-2-ONE;Torin 1;Benzo[h]-1,6-naphthyridin-2(1H)-one, 1-[4-[4-(1-oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-;1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one Torin 1;Torin 1 1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one;1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one;Torin 1, >=98%
62 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1unit
- 10mg
- 10
- 5MG
- 10.00mg
- 25.00mg
- 25MG
- 50.00mg
- 50mg
- 200mg
- 50
- 100MG
- 250mg
- 500mg
- 1G
- 10mM*1mLinDMSO
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging5MG
- Price$75
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging5MG
- Price$75
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging25MG
- Price$215
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging25MG
- Price$215
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging100MG
- Price$650
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging100MG
- Price$650
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging1G
- Price$2150
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging1G
- Price$2150
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0294
- Product descriptionTorin1
- Packaging50mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0294
- Product descriptionTorin1
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8312
- Product descriptionTorin1
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8312
- Product descriptionTorin1
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8312
- Product descriptionTorin1
- Packaging25mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-13003
- Product descriptionTorin1 99.28%
- Packaging25mg
- Price$240
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-13003
- Product descriptionTorin1 99.28%
- Packaging50mg
- Price$380
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-13003
- Product descriptionTorin1 99.28%
- Packaging5mg
- Price$80
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | 10730 | Torin 1 98% | 5MG | $75 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10730 | Torin 1 98% | 5MG | $75 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10730 | Torin 1 98% | 25MG | $215 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10730 | Torin 1 98% | 25MG | $215 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10730 | Torin 1 98% | 100MG | $650 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10730 | Torin 1 98% | 100MG | $650 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10730 | Torin 1 98% | 1G | $2150 | 2026-05-25 | Buy |
| ACHEMBLOCK | 10730 | Torin 1 98% | 1G | $2150 | 2026-05-27 | Buy |
| AK Scientific | Y0294 | Torin1 | 50mg | $640 | 2021-12-16 | Buy |
| AK Scientific | Y0294 | Torin1 | 10mg | $218 | 2021-12-16 | Buy |
| ApexBio Technology | A8312 | Torin1 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8312 | Torin1 | 5mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | A8312 | Torin1 | 25mg | $270 | 2021-12-16 | Buy |
| Arctom | HY-13003 | Torin1 99.28% | 25mg | $240 | 2026-05-26 | Buy |
| Arctom | HY-13003 | Torin1 99.28% | 50mg | $380 | 2026-05-26 | Buy |
| Arctom | HY-13003 | Torin1 99.28% | 5mg | $80 | 2026-05-26 | Buy |
Properties
Melting point :>223°C (dec.)
Boiling point :817.2±65.0 °C(Predicted)
Density :1.362
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 8 mg/ml).
form :Yellowish-white powder
pka :4.19±0.20(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :AKCRNFFTGXBONI-UHFFFAOYSA-N
SMILES :N1(C2=CC=C(N3CCN(C(=O)CC)CC3)C(C(F)(F)F)=C2)C2=C(C=NC3=CC=C(C4=CC5C(N=C4)=CC=CC=5)C=C32)C=CC1=O
Boiling point :817.2±65.0 °C(Predicted)
Density :1.362
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 8 mg/ml).
form :Yellowish-white powder
pka :4.19±0.20(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :AKCRNFFTGXBONI-UHFFFAOYSA-N
SMILES :N1(C2=CC=C(N3CCN(C(=O)CC)CC3)C(C(F)(F)F)=C2)C2=C(C=NC3=CC=C(C4=CC5C(N=C4)=CC=CC=5)C=C32)C=CC1=O
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-fold selectivity for mTOR over PI3Kα and other PI3K-like kinases, including ATM, DNA-PK, and hVps34, as well as 450 other protein kinases. Torin 1, is efficacious at a dose of 20 mg/kg in inhibiting downstream effectors of mTOR in mice.Related product price
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![1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one](https://img.chemicalbook.com/ProductImageEN/2018-12/small/a8d9b725-3501-41e9-8ab0-ffa7fdbdccca.jpg){kind=small}