Ketoconazole

Melting point :148-152 °C
Boiling point :753.4±60.0 °C(Predicted)
Density :1.4046 (rough estimate)
refractive index :-10.5 ° (C=0.4, CHCl3)
Flash point :9℃
storage temp. :2-8°C
solubility :methanol: soluble50mg/mL
pka :pKa 3.25/6.22(H2O,t =25,I=0.025) (Uncertain)
form :Off-white solid
color :white to light yellow
optical activity :[α]20/D -1 to 1°, c = 4 in methanol
Water Solubility :Soluble in DMSO, ethanol, chloroform, water, and methanol.
Merck :14,5302
BCS Class :2
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Major Application :pharmaceutical (small molecule)
InChIKey :XMAYWYJOQHXEEK-OZXSUGGESA-N
SMILES :CC(=O)N1CCN(CC1)c2ccc(OC[C@H]3CO[C@@](Cn4ccnc4)(O3)c5ccc(Cl)cc5Cl)cc2
LogP :4.350
CAS DataBase Reference :65277-42-1(CAS DataBase Reference)

Symbol(GHS):
Signal word:	Danger
Hazard statements:	Code Hazard statements Hazard class Category Signal word Pictogram P-Codes H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501 H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501 H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:	P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P264 Wash hands thoroughly after handling. P264 Wash skin thouroughly after handling. P273 Avoid release to the environment. P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.