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ChemicalBook >> CAS DataBase List >> Ketoconazole

Ketoconazole

Ketoconazole price.
  • $29.4 - $681
  • Product name: Ketoconazole
  • CAS: 65277-42-1
  • MF: C26H28Cl2N4O4
  • MW: 531.43
  • EINECS:265-667-4
  • MDL Number:MFCD00058579
  • Synonyms:Ketoconazole - CAS 65277-42-1 - Calbiochem;,3-dioxolan-4-yl)methoxy)phenyl)-,cis- ;fungarest ;fungoral ;ketoconazol ;ketoderm ;ketoisdin ;kw-1414
18 prices
Selected condition:

Brand

  • Alfa Aesar
  • Cayman Chemical
  • Sigma-Aldrich
  • TCI Chemical

Package

  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 004-1ml
  • k0600000
  • 200mg
  • 500mg
  • 1ml
  • 1g
  • 5x1ml
  • 5g
  • 25g
  • ManufacturerAlfa Aesar
  • Product numberJ67352
  • Product descriptionKetoconazole, 2 mg/ml in methanol, sterile-filtered
  • Packaging1ml
  • Price$29.4
  • Updated2018-11-13
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67352
  • Product descriptionKetoconazole, 2 mg/ml in methanol, sterile-filtered
  • Packaging5x1ml
  • Price$105
  • Updated2018-11-13
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63367
  • Product descriptionKetoconazole, 98%
  • Packaging5g
  • Price$170
  • Updated2018-11-13
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63367
  • Product descriptionKetoconazole, 98%
  • Packaging25g
  • Price$681
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number15212
  • Product descriptionKetoconazole ≥98%
  • Packaging5g
  • Price$338
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number15212
  • Product descriptionKetoconazole ≥98%
  • Packaging1g
  • Price$99
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number15212
  • Product descriptionKetoconazole ≥98%
  • Packaging100mg
  • Price$45
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number15212
  • Product descriptionKetoconazole ≥98%
  • Packaging500mg
  • Price$68
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberK-004
  • Product descriptionKetoconazole solution 2.0 mg/mL in methanol, ampule of 1 mL, certified reference material
  • Packaging004-1ml
  • Price$83.9
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPHR1385
  • Product descriptionKetoconazole Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1g
  • Price$62.3
  • Updated2018-11-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number420600
  • Product descriptionKetoconazole
  • Packaging50mg
  • Price$109
  • Updated2018-11-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberK1003
  • Product descriptionKetoconazole ≥98% (HPLC)
  • Packaging100mg
  • Price$134
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1356508
  • Product descriptionKetoconazole United States Pharmacopeia (USP) Reference Standard
  • Packaging200mg
  • Price$348
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberUC280
  • Product descriptionKetoconazole
  • Packaging10mg
  • Price$388
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberK0600000
  • Product descriptionKetoconazole European Pharmacopoeia (EP) Reference Standard
  • Packagingk0600000
  • Price$179
  • Updated2018-11-23
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberUC280
  • Product descriptionKetoconazole
  • Packaging5mg
  • Price$225
  • Updated2018-11-13
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J67352 Ketoconazole, 2 mg/ml in methanol, sterile-filtered 1ml $29.4 2018-11-13 Buy
Alfa Aesar J67352 Ketoconazole, 2 mg/ml in methanol, sterile-filtered 5x1ml $105 2018-11-13 Buy
Alfa Aesar J63367 Ketoconazole, 98% 5g $170 2018-11-13 Buy
Alfa Aesar J63367 Ketoconazole, 98% 25g $681 2018-11-13 Buy
Cayman Chemical 15212 Ketoconazole ≥98% 5g $338 2018-11-13 Buy
Cayman Chemical 15212 Ketoconazole ≥98% 1g $99 2018-11-13 Buy
Cayman Chemical 15212 Ketoconazole ≥98% 100mg $45 2018-11-13 Buy
Cayman Chemical 15212 Ketoconazole ≥98% 500mg $68 2018-11-13 Buy
Sigma-Aldrich K-004 Ketoconazole solution 2.0 mg/mL in methanol, ampule of 1 mL, certified reference material 004-1ml $83.9 2018-11-13 Buy
Sigma-Aldrich PHR1385 Ketoconazole Pharmaceutical Secondary Standard; Certified Reference Material 1g $62.3 2018-11-20 Buy
Sigma-Aldrich 420600 Ketoconazole 50mg $109 2018-11-20 Buy
Sigma-Aldrich K1003 Ketoconazole ≥98% (HPLC) 100mg $134 2018-11-13 Buy
Sigma-Aldrich 1356508 Ketoconazole United States Pharmacopeia (USP) Reference Standard 200mg $348 2018-11-13 Buy
Sigma-Aldrich UC280 Ketoconazole 10mg $388 2018-11-13 Buy
Sigma-Aldrich K0600000 Ketoconazole European Pharmacopoeia (EP) Reference Standard k0600000 $179 2018-11-23 Buy
Sigma-Aldrich UC280 Ketoconazole 5mg $225 2018-11-13 Buy

Properties

Melting point: :146°C
Density  :1.4046 (rough estimate)
refractive index  :-10.5 ° (C=0.4, CHCl3)
Flash point: :9℃
storage temp.  :2-8°C
solubility  :methanol: soluble50mg/mL
pka :pKa 3.25/6.22(H2O,t =25,I=0.025) (Uncertain)
form  :Off-white solid
color  :white to light yellow
optical activity :[α]20/D -1 to 1°, c = 4 in methanol
Water Solubility  :Soluble in DMSO, ethanol, chloroform, water, and methanol.
Merck  :14,5302
CAS DataBase Reference :65277-42-1(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning P273, P391, P501
H402 Harmful to aquatic life Hazardous to the aquatic environment, acute hazard Category 3
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P201 Obtain special instructions before use.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P311 Call a POISON CENTER or doctor/physician.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Ketoconazole is an orally active broad spectrum antifungal agent that blocks ergosterol biosynthesis by inhibiting the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol 14α-demethylase. It potently inhibits the mammalian analog CYP51A1 (IC50 = 63.5 nM), as well as a variety of other CYP isoforms.

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