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ChemicalBook >> CAS DataBase List >> LDC4297

LDC4297

$18 - $3795
Product name: LDC4297
CAS: 1453834-21-3
MF: C23H28N8O
MW: 432.52
EINECS:
MDL Number:MFCD28411427
Synonyms:LDC4297;LDC4297(LDC044297);LDC044297;LDC4297;LDC 4297;CS-2539;CS-2540;Pyrazolo[1,5-a]-1,3,5-triazin-4-amine, 8-(1-methylethyl)-2-(3-piperidinyloxy)-N-[[2-(1H-pyrazol-1-yl)phenyl]methyl]-;N-(2-(1H-Pyrazol-1-yl)benzyl)-8-isopropyl-2-(piperidin-3-yloxy)pyrazolo[1,5-a][1,3,5]triazin-4-amine

Price38 Properties Safety Information Description

38 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
Biosynth
Cayman Chemical
ChemScene
DC Chemicals
TRC

Package

10mM*1mLinDMSO(Solution)
1mg
2mg
5mg
10mg
25mg
50mg
100mg
250mg
1G
10mM*1mLinDMSO(Solid+Solvent)

Manufactureraablocks
Product numberAA01E233
Product descriptionN-(2-(1H-Pyrazol-1-Yl)Benzyl)-8-Isopropyl-2-(Piperidin-3-Yloxy)Pyrazolo[1,5-A][1,3,5]Triazin-4-Amine ≥98%
Packaging10mg
Price$68
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01E233
Product descriptionN-(2-(1H-Pyrazol-1-Yl)Benzyl)-8-Isopropyl-2-(Piperidin-3-Yloxy)Pyrazolo[1,5-A][1,3,5]Triazin-4-Amine 98+%
Packaging1mg
Price$18
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01E233
Product descriptionN-(2-(1H-Pyrazol-1-Yl)Benzyl)-8-Isopropyl-2-(Piperidin-3-Yloxy)Pyrazolo[1,5-A][1,3,5]Triazin-4-Amine 98+%
Packaging5mg
Price$37
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01E233
Product descriptionN-(2-(1H-Pyrazol-1-Yl)Benzyl)-8-Isopropyl-2-(Piperidin-3-Yloxy)Pyrazolo[1,5-A][1,3,5]Triazin-4-Amine ≥98%
Packaging50mg
Price$193
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01E233
Product descriptionN-(2-(1H-Pyrazol-1-Yl)Benzyl)-8-Isopropyl-2-(Piperidin-3-Yloxy)Pyrazolo[1,5-A][1,3,5]Triazin-4-Amine ≥98%
Packaging100mg
Price$330
Updated2026-05-30
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ManufacturerACHEMBLOCK
Product numberP51730
Product descriptionN-(2-(1H-pyrazol-1-yl)benzyl)-8-isopropyl-2-(piperidin-3-yloxy)pyrazolo[1,5-a][1,3,5]triazin-4-amine 98%
Packaging100MG
Price$260
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberP51730
Product descriptionN-(2-(1H-pyrazol-1-yl)benzyl)-8-isopropyl-2-(piperidin-3-yloxy)pyrazolo[1,5-a][1,3,5]triazin-4-amine 98%
Packaging1G
Price$1300
Updated2026-05-27
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ManufacturerAK Scientific
Product number1333DY
Product descriptionCID78161839
Packaging25mg
Price$735
Updated2021-12-16
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ManufacturerAK Scientific
Product number1333DY
Product descriptionCID78161839
Packaging1mg
Price$139
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberBA1912
Product descriptionLDC4297
Packaging10mg
Price$112
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberBA1912
Product descriptionLDC4297
Packaging25mg
Price$225
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberBA1912
Product descriptionLDC4297
Packaging5mg
Price$70
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberBA1912
Product descriptionLDC4297
Packaging50mg
Price$360
Updated2026-05-06
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ManufacturerArctom
Product numberHY-12653
Product descriptionLDC4297 98.14%
Packaging50mg
Price$333
Updated2026-05-26
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ManufacturerArctom
Product numberHY-12653
Product descriptionLDC4297 98.14%
Packaging5mg
Price$75
Updated2026-05-26
Buy

ManufacturerArctom
Product numberHY-12653
Product descriptionLDC4297 98.14%
Packaging10mM*1mLinDMSO(Solid+Solvent)
Price$77
Updated2026-05-26
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA01E233	N-(2-(1H-Pyrazol-1-Yl)Benzyl)-8-Isopropyl-2-(Piperidin-3-Yloxy)Pyrazolo[1,5-A][1,3,5]Triazin-4-Amine ≥98%	10mg	$68	2026-05-30	Buy
aablocks	AA01E233	N-(2-(1H-Pyrazol-1-Yl)Benzyl)-8-Isopropyl-2-(Piperidin-3-Yloxy)Pyrazolo[1,5-A][1,3,5]Triazin-4-Amine 98+%	1mg	$18	2026-05-30	Buy
aablocks	AA01E233	N-(2-(1H-Pyrazol-1-Yl)Benzyl)-8-Isopropyl-2-(Piperidin-3-Yloxy)Pyrazolo[1,5-A][1,3,5]Triazin-4-Amine 98+%	5mg	$37	2026-05-30	Buy
aablocks	AA01E233	N-(2-(1H-Pyrazol-1-Yl)Benzyl)-8-Isopropyl-2-(Piperidin-3-Yloxy)Pyrazolo[1,5-A][1,3,5]Triazin-4-Amine ≥98%	50mg	$193	2026-05-30	Buy
aablocks	AA01E233	N-(2-(1H-Pyrazol-1-Yl)Benzyl)-8-Isopropyl-2-(Piperidin-3-Yloxy)Pyrazolo[1,5-A][1,3,5]Triazin-4-Amine ≥98%	100mg	$330	2026-05-30	Buy
ACHEMBLOCK	P51730	N-(2-(1H-pyrazol-1-yl)benzyl)-8-isopropyl-2-(piperidin-3-yloxy)pyrazolo[1,5-a][1,3,5]triazin-4-amine 98%	100MG	$260	2026-05-27	Buy
ACHEMBLOCK	P51730	N-(2-(1H-pyrazol-1-yl)benzyl)-8-isopropyl-2-(piperidin-3-yloxy)pyrazolo[1,5-a][1,3,5]triazin-4-amine 98%	1G	$1300	2026-05-27	Buy
AK Scientific	1333DY	CID78161839	25mg	$735	2021-12-16	Buy
AK Scientific	1333DY	CID78161839	1mg	$139	2021-12-16	Buy
ApexBio Technology	BA1912	LDC4297	10mg	$112	2026-05-06	Buy
ApexBio Technology	BA1912	LDC4297	25mg	$225	2026-05-06	Buy
ApexBio Technology	BA1912	LDC4297	5mg	$70	2026-05-06	Buy
ApexBio Technology	BA1912	LDC4297	50mg	$360	2026-05-06	Buy
Arctom	HY-12653	LDC4297 98.14%	50mg	$333	2026-05-26	Buy
Arctom	HY-12653	LDC4297 98.14%	5mg	$75	2026-05-26	Buy
Arctom	HY-12653	LDC4297 98.14%	10mM*1mLinDMSO(Solid+Solvent)	$77	2026-05-26	Buy

Next Last

Properties

Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:20.0(Max Conc. mg/mL);46.24(Max Conc. mM)
DMSO:40.0(Max Conc. mg/mL);92.48(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);46.24(Max Conc. mM) form :A crystalline solid
pka :8.69±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):

Signal word:

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

Precautionary statements:

Description

LDC-4297 is an inhibitor of cyclin-dependent kinase 7 (CDK7; IC₅₀ = <5 nM). It is selective for CDK7 over CDK4, CDK6, and CDK9 (IC₅₀s = >10, >10, and 1.71 μM), however, it also inhibits CDK2 and CDK1 (IC₅₀s = 6.4 and 53.7 nM, respectively). LDC-4297 (10-100 nM) induces apoptosis in A549, HeLa, and HCT116 cancer cells in a concentration-dependent manner. It inhibits human cytomegalovirus (HCMV) replication in human fibroblasts (EC₅₀ = 24.5 nM). LDC-4297 also reduces replication of Herpesviridae, Adenoviridae, Poxviridae, Retroviridae, and Orthomyxoviridae family viruses (EC₅₀s = 0.02-1.13 μM).

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. BOC Sciences Shanghai JiYi Biotechnology Co. Ltd. Shanghai Lollane Biological Technology Co.,Ltd. Shanghai YuanYe Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Beijing Solarbio Science & Tecnology Co., Ltd. Amadis Chemical Company Limited Shanghai Biopharmaleader Co., Ltd. Angel Pharmatech, Ltd.

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LDC4297

Properties

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Description

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