LEI-106
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- $45 - $850
- Product name: LEI-106
- CAS: 1620582-23-1
- MF: C26H27NO6S
- MW: 481.56
- EINECS:
- MDL Number:
- Synonyms:LEI-106;FOEGBOXMDBPYEV-UHFFFAOYSA-N;LEI106,LEI 106;Glycine, N-[(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)sulfonyl]-N-[(4-phenoxyphenyl)methyl]-
7 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- ManufacturerAK Scientific
- Product number5409ED
- Product description2-[(2,2-Dimethyl-3,4-dihydrochromen-6-yl)sulfonyl-[(4-phenoxyphenyl)methyl]amino]aceticacid
- Packaging5mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16419
- Product descriptionLEI-106 ≥98%
- Packaging1mg
- Price$45
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16419
- Product descriptionLEI-106 ≥98%
- Packaging5mg
- Price$133
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16419
- Product descriptionLEI-106 ≥98%
- Packaging10mg
- Price$234
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16419
- Product descriptionLEI-106 ≥98%
- Packaging25mg
- Price$510
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number59482
- Product descriptionLEI-106
- Packaging25mg
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberL320500
- Product descriptionLEI-106
- Packaging10mg
- Price$185
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5409ED | 2-[(2,2-Dimethyl-3,4-dihydrochromen-6-yl)sulfonyl-[(4-phenoxyphenyl)methyl]amino]aceticacid | 5mg | $245 | 2021-12-16 | Buy |
| Cayman Chemical | 16419 | LEI-106 ≥98% | 1mg | $45 | 2024-03-01 | Buy |
| Cayman Chemical | 16419 | LEI-106 ≥98% | 5mg | $133 | 2024-03-01 | Buy |
| Cayman Chemical | 16419 | LEI-106 ≥98% | 10mg | $234 | 2024-03-01 | Buy |
| Cayman Chemical | 16419 | LEI-106 ≥98% | 25mg | $510 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 59482 | LEI-106 | 25mg | $850 | 2021-12-16 | Buy |
| TRC | L320500 | LEI-106 | 10mg | $185 | 2021-12-16 | Buy |
Properties
Boiling point :664.1±65.0 °C(Predicted)
Density :1.288±0.06 g/cm3(Predicted)
solubility :DMF: 50 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.1 mg/ml
form :A crystalline solid
pka :2.90±0.10(Predicted)
Density :1.288±0.06 g/cm3(Predicted)
solubility :DMF: 50 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.1 mg/ml
form :A crystalline solid
pka :2.90±0.10(Predicted)
Safety Information
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Description
In humans, two forms of diacylglycerol lipase, DAGLα and DAGLβ, generate the endocannabinoid 2-arachidonoyl glycerol (2-AG; ) by attacking DAG at the sn-1 position. LEI-106 is a potent in vitro inhibitor of sn-1 DAGLα (IC50 = 18 nM). It blocks the hydrolysis of sn-1-oleoyl-2-AG, the natural substrate of DAGLα, with a Ki value of 0.7 μM. LEI-106 inhibits the hydrolysis of 2-AG by the monoacylglycerol lipase ABHD6 in mouse brain membrane homogenates and in HEK293T cell membrane preparations (Ki = 0.8 μM).Suppliers and manufacturers
Shanghai Beckham Medical Technology Co., Ltd
Shanghai Hongye Biotechnology Co. Ltd
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd
Energy Chemical
MedBioPharmaceutical Technology Inc
TargetMol Chemicals Inc.
Shanghai Yifei Biotechnology Co. , Ltd.
Tanmo Quality Inspection Technology Co., Ltd.
