LOVASTATIN-D9
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- $275
- Product name: LOVASTATIN-D9
- CAS: 1002346-03-3
- MF: C24H36O5
- MW: 404.55
- EINECS:
- MDL Number:MFCD08063460
- Synonyms:LOVASTATIN-D9
1 prices
Selected condition：
Brand
- Cayman Chemical
Package
- 1mg
- ManufacturerCayman Chemical
- Product number26461
- Product descriptionLovastatin-d9
- Packaging1mg
- Price$275
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 26461 | Lovastatin-d9 | 1mg | $275 | 2024-03-01 | Buy |
Properties
solubility :Chloroform: slightly soluble
Methanol: slightly soluble
Methanol: slightly soluble
Safety Information
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Description
Lovastatin-d9 is intended for use as an internal standard for the quantification of lovastatin (Item No. 10010338) by GC- or LC-MS. Lovastatin is a fungal metabolite that has been found in A. terreus and an inhibitor of HMG-CoA reductase (Ki = 1.4 nM).1,2 It is also a prodrug form of the HMG-CoA reductase inhibitor lovastatin hydroxy acid (Item No. 10010339).2 Lovastatin (8 mg/kg per day) reduces plasma cholesterol levels in dogs. It suppresses TNF-induced NF-κB activation (IC50 = ~15 µM) and potentiates apoptosis in human myeloid leukemia cells.3 Lovastatin also increases cellular lipid peroxidation and decreases glutathione peroxidase 4 (GPX4) levels in cancer cells.4 Formulations containing lovastatin have been used in the treatment of hypercholesterolemia.WARNING This product is not for human or veterinary use.More related product prices
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