Lometrexol
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- $85 - $8567
- Product name: Lometrexol
- CAS: 106400-81-1
- MF: C21H25N5O6
- MW: 443.45
- EINECS:
- MDL Number:
- Synonyms:Lometrexol;(6R)-5,10-Dideaza-5,6,7,8-tetrahydrofolic acid;N-[4-[2-[[(6R)-2-Amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin]-6-yl]ethyl]benzoyl]-L-glutamic acid;N-[4-[2-[[(R)-2-Amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin]-6-yl]ethyl]benzoyl]-L-glutamic acid;L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-D)pyrimidin-6-yl)ethyl)benzoyl)-;L-Glutamic acid, N-(4-(2-(2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-D)pyrimidin-6-yl)ethyl)benzoyl)-, (R)-;Lometrexolum;Lometrexolum [inn-latin]
48 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- American Custom Chemicals Corporation
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 2.5mg
- 1mg
- 10mM*1mLinDMSO(Solution)
- 5mg
- 10mg
- 25MG
- 50mg
- 100MG
- Manufactureraablocks
- Product numberAA008WSZ
- Product descriptionLometrexol
- Packaging1mg
- Price$85
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008WSZ
- Product descriptionLometrexol
- Packaging5mg
- Price$179
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008WSZ
- Product descriptionLometrexol
- Packaging10mg
- Price$283
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226733
- Product descriptionLometrexol 97.00%
- Packaging5MG
- Price$235
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226733
- Product descriptionLometrexol 97.00%
- Packaging25MG
- Price$670
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226733
- Product descriptionLometrexol 97.00%
- Packaging100MG
- Price$1380
- Updated2026-05-27
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0027262
- Product descriptionLOMETREXOL HYDRATE 95.00%
- Packaging5MG
- Price$500.35
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-14521
- Product descriptionLometrexol 98.96%
- Packaging10mg
- Price$380
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14521
- Product descriptionLometrexol 98.96%
- Packaging25mg
- Price$646
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14521
- Product descriptionLometrexol 98.96%
- Packaging50mg
- Price$1045
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14521
- Product descriptionLometrexol 98.96%
- Packaging5mg
- Price$238
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14521
- Product descriptionLometrexol 98.96%
- Packaging1mg
- Price$95
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14521
- Product descriptionLometrexol 98.96%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$248
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14521
- Product descriptionLometrexol 98.96%
- Packaging10mM*1mLinDMSO(Solution)
- Price$262
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14521
- Product descriptionLometrexol 98.96%
- Packaging100mg
- Price$1672
- Updated2026-05-26
- Buy
- ManufacturerBiosynth
- Product numberGEA40081
- Product descriptionLometrexol Hydrate
- Packaging25mg
- Price$2284.5
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008WSZ | Lometrexol | 1mg | $85 | 2026-05-28 | Buy |
| aablocks | AA008WSZ | Lometrexol | 5mg | $179 | 2026-05-28 | Buy |
| aablocks | AA008WSZ | Lometrexol | 10mg | $283 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y226733 | Lometrexol 97.00% | 5MG | $235 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y226733 | Lometrexol 97.00% | 25MG | $670 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y226733 | Lometrexol 97.00% | 100MG | $1380 | 2026-05-27 | Buy |
| American Custom Chemicals Corporation | API0027262 | LOMETREXOL HYDRATE 95.00% | 5MG | $500.35 | 2021-12-16 | Buy |
| Arctom | HY-14521 | Lometrexol 98.96% | 10mg | $380 | 2026-05-26 | Buy |
| Arctom | HY-14521 | Lometrexol 98.96% | 25mg | $646 | 2026-05-26 | Buy |
| Arctom | HY-14521 | Lometrexol 98.96% | 50mg | $1045 | 2026-05-26 | Buy |
| Arctom | HY-14521 | Lometrexol 98.96% | 5mg | $238 | 2026-05-26 | Buy |
| Arctom | HY-14521 | Lometrexol 98.96% | 1mg | $95 | 2026-05-26 | Buy |
| Arctom | HY-14521 | Lometrexol 98.96% | 10mM*1mLinDMSO(Solid+Solvent) | $248 | 2026-05-26 | Buy |
| Arctom | HY-14521 | Lometrexol 98.96% | 10mM*1mLinDMSO(Solution) | $262 | 2026-05-26 | Buy |
| Arctom | HY-14521 | Lometrexol 98.96% | 100mg | $1672 | 2026-05-26 | Buy |
| Biosynth | GEA40081 | Lometrexol Hydrate | 25mg | $2284.5 | 2026-06-04 | Buy |
Properties
Density :1.56±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
form :powder
pka :3.60±0.10(Predicted)
color :white to light yellow
Stability :Hygroscopic
InChIKey :AEFQSKJUVDZANQ-YLCXCWDSSA-N
SMILES :O.NC1=NC(=O)C2=C(NC[C@H](CCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)C2)N1
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
form :powder
pka :3.60±0.10(Predicted)
color :white to light yellow
Stability :Hygroscopic
InChIKey :AEFQSKJUVDZANQ-YLCXCWDSSA-N
SMILES :O.NC1=NC(=O)C2=C(NC[C@H](CCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)C2)N1
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Glycinamide ribonucleotide formyltransferase (GART) is a folate-dependent enzyme required for de novo purine synthesis. Lometrexol is a folate analog antimetabolite with antineoplastic activity. At nanomolar conentrations, it inhibits GART preventing de novo purine synthesis, inhibiting DNA synthesis, arresting cells in the S phase of the cell cycle, and inhibiting tumor cell proliferation.Related product price
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