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ChemicalBook >> CAS DataBase List >> Lopinavir-d8

Lopinavir-d8

Lopinavir-d8 price.
  • $456 - $2080
  • Product name: Lopinavir-d8
  • CAS: 1322625-54-6
  • MF: C37H40D8N4O5
  • MW: 636.850114224
  • EINECS:
  • MDL Number:
  • Synonyms:LOPINAVIR-D8;2,3,4,4,4-pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 1mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number5704DV
  • Product description2,3,4,4,4-Pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide
  • Packaging1mg
  • Price$606
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25284
  • Product descriptionLopinavir-d8 ≥99% deuterated forms (d1-d8)
  • Packaging1mg
  • Price$456
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberL469482
  • Product descriptionLopinavir-d8
  • Packaging10mg
  • Price$2080
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberL3420-31
  • Product descriptionLopinavir-d8
  • Packaging1mg
  • Price$566
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5704DV 2,3,4,4,4-Pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide 1mg $606 2021-12-16 Buy
Cayman Chemical 25284 Lopinavir-d8 ≥99% deuterated forms (d1-d8) 1mg $456 2024-03-01 Buy
TRC L469482 Lopinavir-d8 10mg $2080 2021-12-16 Buy
Usbiological L3420-31 Lopinavir-d8 1mg $566 2021-12-16 Buy

Properties

Melting point :>96°C (dec.)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :Off-White to Pale Beige
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Lopinavir-d8 is intended for use as an internal standard for the quantification of lopinavir by GC- or LC-MS. Lopinavir is a potent HIV-1 protease inhibitor (Ki = 1.3 pM for wild-type enzyme). It inhibits the replication of clinical isolates of HIV-1 (EC50s = 5-52 nM). Lopinavir reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; EC50s = 26.63 and 26.10 μM, respectively). It reduces lung and kidney viral load, bronchointerstitial pneumonia, and pulmonary inflammatory cell infiltration in a marmoset model of Middle East respiratory syndrome coronavirus (MERS-CoV) infection when administered in combination with ritonavir .

Suppliers and manufacturers

TargetMol Chemicals Inc.
Lopinavir-d8
$0.00 /1mg
Lopinavir-d8 CAS:1322625-54-6
Artis Biotech Co. Ltd. Shanghai EFE Biological Technology Co., Ltd. Nanjing Haolv Biotechnology Co.,Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. Nanjing Shizhou Biology Technology Co.,Ltd Energy Chemical Changzhou Bojia Biomedical Technology Co., Ltd. LGC Science (Shanghai) Ltd. Shanghai Yiyan Biotechnology Co. , Ltd.