Loratadine

Melting point :134-136°C
Boiling point :531.3±50.0 °C(Predicted)
Density :1.261±0.06 g/cm3(Predicted)
RTECS :TM6129200
storage temp. :2-8°C
solubility :DMSO: 26 mg/mL, soluble
form :powder
pka :4.27±0.20(Predicted)
color :white
Water Solubility :It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
Merck :14,5578
BCS Class :2
Stability :Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
InChI :1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
InChIKey :JCCNYMKQOSZNPW-UHFFFAOYSA-N
SMILES :CCOC(=O)N1CC\C(CC1)=C2/c3ccc(Cl)cc3CCc4cccnc24
CAS DataBase Reference :79794-75-5(CAS DataBase Reference)
EPA Substance Registry System :1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5)

Symbol(GHS):
Signal word:	Warning
Hazard statements:	Code Hazard statements Hazard class Category Signal word Pictogram P-Codes H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362 H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:	P264 Wash hands thoroughly after handling. P264 Wash skin thouroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection. P302+P352 IF ON SKIN: wash with plenty of soap and water. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P321 Specific treatment (see … on this label). P332+P313 IF SKIN irritation occurs: Get medical advice/attention. P362 Take off contaminated clothing and wash before reuse.