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ChemicalBook >> CAS DataBase List >> MCTR2

MCTR2

MCTR2 price.
  • $125 - $1199
  • Product name: MCTR2
  • CAS: 1784701-62-7
  • MF: C27H40N2O6S
  • MW: 520.68
  • EINECS:
  • MDL Number:
  • Synonyms:MCTR2;Glycine, S-[(1R,2E,4E,6Z,9Z)-12-carboxy-1-[(1S,3Z,6Z)-1-hydroxy-3,6-nonadien-1-yl]-2,4,6,9-dodecatetraen-1-yl]-L-cysteinyl-;S-?[(1R,?2E,?4E,?6Z,?9Z)?-?12-Carboxy-?1-?[(1S,?3Z,?6Z)?-?1-?hydroxy-?3,?6-?nonadien-?1-?yl]?-?2,?4,?6,?9-?dodecatetraen-?1-?yl]?-?L-?cysteinyl-glycine
5 prices
Selected condition:
Brand
  • Cayman Chemical
  • TRC
Package
  • 10μg
  • 25μg
  • 50μg
  • 100μg
  • 10g
  • ManufacturerCayman Chemical
  • Product number17008
  • Product descriptionMCTR2 ≥97%
  • Packaging10μg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17008
  • Product descriptionMCTR2 ≥97%
  • Packaging25μg
  • Price$362
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17008
  • Product descriptionMCTR2 ≥97%
  • Packaging50μg
  • Price$684
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17008
  • Product descriptionMCTR2 ≥97%
  • Packaging100μg
  • Price$1199
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC178710
  • Product descriptionS-​[(1R,​2E,​4E,​6Z,​9Z)​-​12-Carboxy-​1-​[(1S,​3Z,​6Z)​-​1-​hydroxy-​3,​6-​nonadien-​1-​yl]​-​2,​4,​6,​9-​dodecatetraen-​1-​yl]​-​L-​cysteinyl-glycine
  • Packaging10g
  • Price$125
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 17008 MCTR2 ≥97% 10μg $153 2024-03-01 Buy
Cayman Chemical 17008 MCTR2 ≥97% 25μg $362 2024-03-01 Buy
Cayman Chemical 17008 MCTR2 ≥97% 50μg $684 2024-03-01 Buy
Cayman Chemical 17008 MCTR2 ≥97% 100μg $1199 2024-03-01 Buy
TRC C178710 S-​[(1R,​2E,​4E,​6Z,​9Z)​-​12-Carboxy-​1-​[(1S,​3Z,​6Z)​-​1-​hydroxy-​3,​6-​nonadien-​1-​yl]​-​2,​4,​6,​9-​dodecatetraen-​1-​yl]​-​L-​cysteinyl-glycine 10g $125 2021-12-16 Buy

Properties

Boiling point :801.3±65.0 °C(Predicted)
Density :1.163±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 1 mg/ml; Ethanol:Water (95:5): 2 mg/ml; PBS (pH 7.2): 100 μg/ml
pka :3.03±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA; ) in macrophages at the site of inflammation. DHA is oxidized to maresin 1 (MaR1; ), which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase then to MCTR2 by γ-glutamyl transferase. MCTR2 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR2 prior to E. coli administration reduces neutrophil infiltration, shortens the inflammatory resolution period, and increases phagocytosis of E. coli by macrophages. When administered at a dose of 100 ng 12h post E. coli infection in a mouse model of peritonitis, MCTR2 selectively reduced the amount of the eicosanoids PGD2 and PGF in the exudate.