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ChemicalBook >> CAS DataBase List >> MPEP HYDROCHLORIDE

MPEP HYDROCHLORIDE

MPEP HYDROCHLORIDE price.
  • $49 - $2080
  • Product name: MPEP HYDROCHLORIDE
  • CAS: 219911-35-0
  • MF: C14H11N.ClH
  • MW: 229.709
  • EINECS:
  • MDL Number:MFCD02262119
  • Synonyms:6-methyl-2-(phenylethynyl)pyridine;2-methyl-6-(phenylethynyl)pyridine(MPEP);Pyridine, 6-methyl-2-(phenylethynyl)-;6-Methyl-2-(phenylethynyl)pyridine hydrochloride;Pyridine,2-methyl-6-(2-phenylethynyl)-, hydrochloride (1:1);MPVP replace pvp,White Crystal, New Stock!;MPEP hydrochloride/219911-35-0/99% purity with low price in stock;MPEP Hydrochloride, >98%
20 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 5g
  • ManufacturerAK Scientific
  • Product numberY0463
  • Product description2-Methyl-6-(phenylethynyl)pyridinehydrochloride
  • Packaging5g
  • Price$2080
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA303368
  • Product description2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+%
  • Packaging10mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA303368
  • Product description2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+%
  • Packaging25mg
  • Price$114
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA303368
  • Product description2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+%
  • Packaging50mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3633
  • Product descriptionMPEPHydrochloride
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3633
  • Product descriptionMPEPHydrochloride
  • Packaging50mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS513445
  • Product description2-Methyl-6-(phenylethynyl)pyridinehydrochloride
  • Packaging50mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14536
  • Product descriptionMPEP (hydrochloride) ≥98%
  • Packaging5mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14536
  • Product descriptionMPEP (hydrochloride) ≥98%
  • Packaging10mg
  • Price$82
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14536
  • Product descriptionMPEP (hydrochloride) ≥98%
  • Packaging25mg
  • Price$190
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14536
  • Product descriptionMPEP (hydrochloride) ≥98%
  • Packaging50mg
  • Price$310
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0793
  • Product descriptionMPEPHydrochloride 99.69%
  • Packaging10mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0793
  • Product descriptionMPEPHydrochloride 99.69%
  • Packaging50mg
  • Price$276
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002644
  • Product descriptionMPEPhydrochloride 98+%
  • Packaging50mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8339
  • Product descriptionMPEPhydrochloride >98%
  • Packaging100mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8339
  • Product descriptionMPEPhydrochloride >98%
  • Packaging250mg
  • Price$600
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0463 2-Methyl-6-(phenylethynyl)pyridinehydrochloride 5g $2080 2021-12-16 Buy
Ambeed A303368 2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+% 10mg $68 2021-12-16 Buy
Ambeed A303368 2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+% 25mg $114 2021-12-16 Buy
Ambeed A303368 2-Methyl-6-(phenylethynyl)pyridinehydrochloride 98+% 50mg $148 2021-12-16 Buy
ApexBio Technology A3633 MPEPHydrochloride 10mg $60 2021-12-16 Buy
ApexBio Technology A3633 MPEPHydrochloride 50mg $230 2021-12-16 Buy
Arctom AS513445 2-Methyl-6-(phenylethynyl)pyridinehydrochloride 50mg $147 2021-12-16 Buy
Cayman Chemical 14536 MPEP (hydrochloride) ≥98% 5mg $49 2024-03-01 Buy
Cayman Chemical 14536 MPEP (hydrochloride) ≥98% 10mg $82 2024-03-01 Buy
Cayman Chemical 14536 MPEP (hydrochloride) ≥98% 25mg $190 2024-03-01 Buy
Cayman Chemical 14536 MPEP (hydrochloride) ≥98% 50mg $310 2024-03-01 Buy
ChemScene CS-0793 MPEPHydrochloride 99.69% 10mg $72 2021-12-16 Buy
ChemScene CS-0793 MPEPHydrochloride 99.69% 50mg $276 2021-12-16 Buy
Crysdot CD31002644 MPEPhydrochloride 98+% 50mg $139 2021-12-16 Buy
DC Chemicals DC8339 MPEPhydrochloride >98% 100mg $300 2021-12-16 Buy
DC Chemicals DC8339 MPEPhydrochloride >98% 250mg $600 2021-12-16 Buy

Properties

Melting point :145-146℃
storage temp. :room temp
solubility :DMSO: 10 mg/mL
form :solid
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :PKDHDJBNEKXCBI-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Glutamate, the major excitatory neurotransmitter in the brain, acts on both ionotropic and metabotropic glutamate receptors. Excessive metabotropic glutamate receptor (mGluR) transmission has been linked to epilepsy, ischemia, pain, anxiety, and depression. Eight subtypes (1-8) and multiple splice variants of the mGluR have been identified and grouped based on their pharmacological properties. Group I mGluRs (subtypes 1 and 5) activate the phosphatidyl inositol pathway, while Group II (2 and 3) and Group III (4, 6, 7 and 8) inhibit adenylyl cyclase. MPEP is a potent, highly selective non-competitive antagonist at the mGlu5a receptor subtype (IC50 = 36 nM) while having no agonist or antagonist activities at the mGlu1b receptor at concentrations up to 30 μM. MPEP is centrally active following systemic administration in vivo, inducing anxiolytic-like effects in rodent models of anxiety and depression when administered at 1-30 mg/kg. MPEP has also been reported as a positive allosteric modulator of mGluR4 at μM concentrations.

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