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ChemicalBook >> CAS DataBase List >> MRK 560

MRK 560

$48 - $1500
Product name: MRK 560
CAS: 677772-84-8
MF: C19H17ClF5NO4S2
MW: 517.92
EINECS:
MDL Number:MFCD09970622
Synonyms:N-[cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide;N-((1s,4s)-4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)-1,1,1-trifluoromethanesulfonamide;MRK 560;Methanesulfonamide, N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoro-;MRK-560; MRK560;WDZVWDXOIGQJIO-UJKQEGAGSA-N;MRK-560,Jurkat cells,DND-41,Aβ peptides,MRK560,MRK 560,Gamma secretase,γ-secretase,T-ALL,Inhibitor,inhibit,Alzheimer’s disease,HPB-ALL;MRK-560, 10 mM in DMSO

Price30 Properties Safety Information Description

30 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Biosynth
Cayman Chemical
ChemScene
Sigma-Aldrich
Tocris
TRC

Package

10
1mg
2mg
5mg
10mg
50
25mg
50mg
100mg
10 mg
50 mg

Manufactureraablocks
Product numberAA00FGIM
Product descriptionMRK-560 ≥99%(HPLC)
Packaging10mg
Price$86
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00FGIM
Product descriptionMRK-560
Packaging2mg
Price$48
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00FGIM
Product descriptionMRK-560 ≥99%(HPLC)
Packaging5mg
Price$56
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00FGIM
Product descriptionMRK-560
Packaging25mg
Price$138
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00FGIM
Product descriptionMRK-560
Packaging50mg
Price$240
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA00FGIM
Product descriptionMRK-560
Packaging100mg
Price$404
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberAD251413
Product descriptionMRK-560 98%
Packaging100MG
Price$575
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberAD251413
Product descriptionMRK-560 98%
Packaging25MG
Price$175
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number9133CS
Product descriptionN-[4-(4-Chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide
Packaging5mg
Price$428
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number9133CS
Product descriptionN-[4-(4-Chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide
Packaging25mg
Price$1366
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0010336
Product descriptionN-[CIS-4-[(4-CHLOROPHENYL)SULFONYL]-4-(2,5-DIFLUOROPHENYL)CYCLOHEXYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE 95.00%
Packaging50MG
Price$1478.35
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberAPI0010336
Product descriptionN-[CIS-4-[(4-CHLOROPHENYL)SULFONYL]-4-(2,5-DIFLUOROPHENYL)CYCLOHEXYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE 95.00%
Packaging10MG
Price$806.48
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4405
Product descriptionMRK 560
Packaging5mg
Price$95
Updated2026-05-06
Buy

ManufacturerBiosynth
Product numberFM65096
Product descriptionMRK 560
Packaging2mg
Price$180
Updated2021-12-16
Buy

ManufacturerBiosynth
Product numberFM65096
Product descriptionMRK 560
Packaging5mg
Price$280
Updated2021-12-16
Buy

ManufacturerBiosynth
Product numberFM65096
Product descriptionMRK 560
Packaging25mg
Price$975
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00FGIM	MRK-560 ≥99%(HPLC)	10mg	$86	2026-05-28	Buy
aablocks	AA00FGIM	MRK-560	2mg	$48	2026-05-28	Buy
aablocks	AA00FGIM	MRK-560 ≥99%(HPLC)	5mg	$56	2026-05-28	Buy
aablocks	AA00FGIM	MRK-560	25mg	$138	2026-05-28	Buy
aablocks	AA00FGIM	MRK-560	50mg	$240	2026-05-28	Buy
aablocks	AA00FGIM	MRK-560	100mg	$404	2026-05-28	Buy
ACHEMBLOCK	AD251413	MRK-560 98%	100MG	$575	2026-05-27	Buy
ACHEMBLOCK	AD251413	MRK-560 98%	25MG	$175	2026-05-27	Buy
AK Scientific	9133CS	N-[4-(4-Chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide	5mg	$428	2021-12-16	Buy
AK Scientific	9133CS	N-[4-(4-Chlorophenyl)sulfonyl-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide	25mg	$1366	2021-12-16	Buy
American Custom Chemicals Corporation	API0010336	N-[CIS-4-[(4-CHLOROPHENYL)SULFONYL]-4-(2,5-DIFLUOROPHENYL)CYCLOHEXYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE 95.00%	50MG	$1478.35	2021-12-16	Buy
American Custom Chemicals Corporation	API0010336	N-[CIS-4-[(4-CHLOROPHENYL)SULFONYL]-4-(2,5-DIFLUOROPHENYL)CYCLOHEXYL]-1,1,1-TRIFLUOROMETHANESULFONAMIDE 95.00%	10MG	$806.48	2021-12-16	Buy
ApexBio Technology	A4405	MRK 560	5mg	$95	2026-05-06	Buy
Biosynth	FM65096	MRK 560	2mg	$180	2021-12-16	Buy
Biosynth	FM65096	MRK 560	5mg	$280	2021-12-16	Buy
Biosynth	FM65096	MRK 560	25mg	$975	2021-12-16	Buy

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Properties

Boiling point :580.1±60.0 °C(Predicted)
Density :1.57±0.1 g/cm3(Predicted)
storage temp. :Store at 4°C
solubility :<51.79mg/ml in DMSO; <25.9mg/ml in ethanol
form :solid
pka :5.97±0.40(Predicted)
color :White

Safety Information

Symbol(GHS):

Signal word:

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

Precautionary statements:

Description

MRK-560 is a potent inhibitor of γ-secretase (IC₅₀ = 0.65 nM). In vivo, MRK-560 (1-10 mg/kg) reduces diethanolamine-soluble amyloid-β (1-40) (Aβ40) levels in APP-YAC transgenic mouse brain. MRK-560 reduces brain and cerebrospinal fluid Aβ40 levels in rats (ED₅₀s = 6 and 10 mg/kg, respectively). It also decreases brain-soluble Aβ40 and Aβ42 levels and recovers hippocampal long-term potentiation in the Tg2576 transgenic mouse model of Alzheimer''s disease.

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Suppliers and manufacturers

TargetMol Chemicals Inc.

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MRK-560 CAS:677772-84-8

Wuhan Topule Biopharmaceutical Co., Ltd

Aladdin Scientific BOC Sciences Nanjing Dulai Biotechnology Co., Ltd. ShangHai Caerulum Pharma Discovery Co., Ltd. Shanghai Beckham Medical Technology Co., Ltd EMMX Biotechnology LLC Shanghai YuanYe Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd

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MRK 560

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