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ChemicalBook >> NF449

NF449

NF449 price.
  • $140.7 - $992
  • Product name: NF449
  • CAS: 389142-38-5
  • MF: C41H32N6O29S8
  • MW: 1329.24
  • EINECS:
  • MDL Number:MFCD02179205
  • Synonyms:4,4',4'',4'''-[CARBONYLBIS(IMINO-5,1,3-BENZENETRIYL-BIS(CARBONYLIMINO))]TETRAKIS-1,3-BENZENEDISULFONIC ACID, OCTASODIUM SALT;4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYL-IMINO)]]TETRAKIS(BENZENE-1,3-DISULFONIC ACID) OCTASODIUM SALT;4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYLIMINO)]]TETRAKIS-(BENZENE-1,3-DISULFONIC ACID, 8NA);NF449;NF449 OCTASODIUM SALT;4,4',4'',4'''-(Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino)))tetrakis-1,3-benzenedisulfonicacid,octasodium;4,4μ,4,4μ-[Carbonylbis[imino-5,1,3-benzenetriyl bis(carbonyl-imino)]]tetrakis(benzene-1,3-disulfonic acid) octasodium salt;NF449 - CAS 389142-38-5 - Calbiochem
7 prices
Selected condition:

Brand

  • American Custom Chemicals Corporation
  • Sigma-Aldrich
  • Tocris
  • Usbiological

Package

  • 50
  • 1MG
  • 5MG
  • 10
  • 10mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009857
  • Product descriptionNF 449 95.00%
  • Packaging1MG
  • Price$140.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009857
  • Product descriptionNF 449 95.00%
  • Packaging5MG
  • Price$505.16
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number480420
  • Product descriptionNF449
  • Packaging10mg
  • Price$227.55
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number1391
  • Product descriptionNF449
  • Packaging10
  • Price$236
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number1391
  • Product descriptionNF449
  • Packaging50
  • Price$992
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number165610
  • Product descriptionNF449
  • Packaging10mg
  • Price$403
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255975
  • Product descriptionNF 449
  • Packaging10mg
  • Price$489
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0009857 NF 449 95.00% 1MG $140.7 2021-12-16 Buy
American Custom Chemicals Corporation API0009857 NF 449 95.00% 5MG $505.16 2021-12-16 Buy
Sigma-Aldrich 480420 NF449 10mg $227.55 2021-12-16 Buy
Tocris 1391 NF449 10 $236 2021-12-16 Buy
Tocris 1391 NF449 50 $992 2021-12-16 Buy
Usbiological 165610 NF449 10mg $403 2021-12-16 Buy
Usbiological 255975 NF 449 10mg $489 2021-12-16 Buy

Properties

storage temp.  :2-8°C
solubility  :H2O: soluble
form  :solid
color  :white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

NF 449 is a selective Gsα-subunit G-protein antagonist which reduces the association rate of guanosine 5'-[γ-thio]triphosphate ([35S]GTP[γS]) binding to Gα s -s (Gs&alpha-s) and inhibits the stimulation of adenylyl cyclase activity in S49 cyc- membranes. In addition, NF 449 interferes with binding between the Adenosine A1-R (A1-adenosine receptor) and its cognate G proteins (Gi/Go). Alternate studies suggest that NF449 inhibits a wide array of P2 receptors such as P2X3, P2Y1, and P2Y2, while showing the highest selectivity towards P2X1. Furthermore, NF449 can disrupt the coupling of β-AR (β-adrenergic receptors).

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