NSC 55712
|
- $49 - $1500
- Product name: NSC 55712
- CAS: 2076-91-7
- MF: C8H14Cl2N4S3
- MW: 333.32456
- EINECS:
- MDL Number:MFCD25976641
- Synonyms:NSC 55712;TPT-260 (Dihydrochloride);THIOPHENE-2,5-DIYLBIS(METHYLENE) DICARBAMIMIDOTHIOATE.2HCL;TPT-260 (Dihydrochloride), NSC55712;TPT-260 2HCl;Carbamimidothioic acid 2,5-thiophenediylbis(methylene) ester dihydrochloride;TPT-260 , NSC55712;NSC 55712 Carbamimidothioic acid 2,5-thiophenediylbis(methylene) ester dihydrochloride
35 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA002J3I
- Product descriptionTPT-260 Dihydrochloride ≥95%
- Packaging1mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002J3I
- Product descriptionTPT-260 Dihydrochloride ≥98%
- Packaging5mg
- Price$63
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002J3I
- Product descriptionTPT-260 Dihydrochloride ≥98%
- Packaging10mg
- Price$112
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002J3I
- Product descriptionTPT-260 Dihydrochloride ≥98%
- Packaging25mg
- Price$244
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002J3I
- Product descriptionTPT-260 Dihydrochloride ≥98%
- Packaging50mg
- Price$411
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002J3I
- Product descriptionTPT-260 Dihydrochloride ≥98%
- Packaging100mg
- Price$698
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33861
- Product descriptionTPT-260 dihydrochloride 98%
- Packaging100MG
- Price$490
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33861
- Product descriptionTPT-260 dihydrochloride 98%
- Packaging25MG
- Price$210
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5349
- Product descriptionR55
- Packaging10mg
- Price$217
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5349
- Product descriptionR55
- Packaging50mg
- Price$757
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3385
- Product descriptionTPT-260 Dihydrochloride
- Packaging100mg
- Price$1087
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB3385
- Product descriptionTPT-260 Dihydrochloride
- Packaging50mg
- Price$652
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB3385
- Product descriptionTPT-260 Dihydrochloride
- Packaging10mg
- Price$217
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB3385
- Product descriptionTPT-260 Dihydrochloride
- Packaging5mg
- Price$130
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberAS019301
- Product descriptionTPT-260Dihydrochloride 98%
- Packaging1g
- Price$1428
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS019301
- Product descriptionTPT-260Dihydrochloride 98%
- Packaging250mg
- Price$572
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002J3I | TPT-260 Dihydrochloride ≥95% | 1mg | $49 | 2026-05-28 | Buy |
| aablocks | AA002J3I | TPT-260 Dihydrochloride ≥98% | 5mg | $63 | 2026-05-28 | Buy |
| aablocks | AA002J3I | TPT-260 Dihydrochloride ≥98% | 10mg | $112 | 2026-05-28 | Buy |
| aablocks | AA002J3I | TPT-260 Dihydrochloride ≥98% | 25mg | $244 | 2026-05-28 | Buy |
| aablocks | AA002J3I | TPT-260 Dihydrochloride ≥98% | 50mg | $411 | 2026-05-28 | Buy |
| aablocks | AA002J3I | TPT-260 Dihydrochloride ≥98% | 100mg | $698 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33861 | TPT-260 dihydrochloride 98% | 100MG | $490 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33861 | TPT-260 dihydrochloride 98% | 25MG | $210 | 2026-05-27 | Buy |
| AK Scientific | SYN5349 | R55 | 10mg | $217 | 2021-12-16 | Buy |
| AK Scientific | SYN5349 | R55 | 50mg | $757 | 2021-12-16 | Buy |
| ApexBio Technology | B3385 | TPT-260 Dihydrochloride | 100mg | $1087 | 2026-05-06 | Buy |
| ApexBio Technology | B3385 | TPT-260 Dihydrochloride | 50mg | $652 | 2026-05-06 | Buy |
| ApexBio Technology | B3385 | TPT-260 Dihydrochloride | 10mg | $217 | 2026-05-06 | Buy |
| ApexBio Technology | B3385 | TPT-260 Dihydrochloride | 5mg | $130 | 2026-05-06 | Buy |
| Arctom | AS019301 | TPT-260Dihydrochloride 98% | 1g | $1428 | 2021-12-16 | Buy |
| Arctom | AS019301 | TPT-260Dihydrochloride 98% | 250mg | $572 | 2021-12-16 | Buy |
Properties
Melting point :210℃ (Decomposition)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO:62.5(Max Conc. mg/mL);240.02(Max Conc. mM)
form :A crystalline solid
color :Light yellow to yellow
Water Solubility :water: 50mg/mL
InChIKey :DSODRWWHAUGSGD-UHFFFAOYSA-N
SMILES :[s]1c(ccc1CSC(=[N+H2])N)CSC(=[N+H2])N.[Cl-].[Cl-]
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO:62.5(Max Conc. mg/mL);240.02(Max Conc. mM)
form :A crystalline solid
color :Light yellow to yellow
Water Solubility :water: 50mg/mL
InChIKey :DSODRWWHAUGSGD-UHFFFAOYSA-N
SMILES :[s]1c(ccc1CSC(=[N+H2])N)CSC(=[N+H2])N.[Cl-].[Cl-]
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Retromers are multiprotein complexes responsible for trafficking cargo out of endosomes. This is an important function that, in the case of amyloid-precursor protein (APP), is neuroprotective by preventing APP from being cleaved into Alzheimer’s disease-inducing fragments via the endosome. TPT-260 is a thiophene thiourea derivative that acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~5 μM). In cultured hippocampal neurons, TPT-260 dose-dependently increases the level of retromer proteins, redirects APP from the endosome, and reduces the formation of pathogenic APP.More related product prices
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