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ChemicalBook >> CAS DataBase List >> NU 2058

NU 2058

NU 2058 price.
  • $54 - $2455.22
  • Product name: NU 2058
  • CAS: 161058-83-9
  • MF: C12H17N5O
  • MW: 247.3
  • EINECS:
  • MDL Number:MFCD05664734
  • Synonyms:6-(Cyclohexylmethoxy)-9H-purin-2-amine;2-aMino-6-purine;2-aMino-6-[(cyclohexylMethyl)oxy]purine;2-Amino-6-(cyclohexylmethoxy)purine;CS-2601;NU 2058;NU-2058;NU2058;NU-2058;O6-(CYCLOHEXYLMETHYL)GUANINE;NU2058>
Price39 Properties Safety Information Description
39 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 10mg
  • 20mg
  • 5mg
  • 1mL(10mMinDMSO)
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 100G
  • ManufacturerAK Scientific
  • Product number0515CA
  • Product description6-O-Cyclohexylmethylguanine
  • Packaging100mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0515CA
  • Product description6-O-Cyclohexylmethylguanine
  • Packaging1g
  • Price$456
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA168683
  • Product descriptionNU 2058 98+%
  • Packaging1g
  • Price$1292
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA168683
  • Product descriptionNU 2058 98+%
  • Packaging100mg
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA168683
  • Product descriptionNU 2058 98+%
  • Packaging50mg
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA168683
  • Product descriptionNU 2058 98+%
  • Packaging5mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA168683
  • Product descriptionNU 2058 98+%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA168683
  • Product descriptionNU 2058 98+%
  • Packaging25mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001281
  • Product descriptionNU 2058 95.00%
  • Packaging100G
  • Price$2455.22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001281
  • Product descriptionNU 2058 95.00%
  • Packaging10MG
  • Price$697.34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001281
  • Product descriptionNU 2058 95.00%
  • Packaging50MG
  • Price$1170.31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001281
  • Product descriptionNU 2058 95.00%
  • Packaging5MG
  • Price$435
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3824
  • Product descriptionNU2058
  • Packaging50mg
  • Price$230
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3824
  • Product descriptionNU2058
  • Packaging100mg
  • Price$360
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3824
  • Product descriptionNU2058
  • Packaging1mL(10mMinDMSO)
  • Price$55
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberBA3824
  • Product descriptionNU2058
  • Packaging10mg
  • Price$86
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0515CA 6-O-Cyclohexylmethylguanine 100mg $138 2021-12-16 Buy
AK Scientific 0515CA 6-O-Cyclohexylmethylguanine 1g $456 2021-12-16 Buy
Ambeed A168683 NU 2058 98+% 1g $1292 2021-12-16 Buy
Ambeed A168683 NU 2058 98+% 100mg $152 2021-12-16 Buy
Ambeed A168683 NU 2058 98+% 50mg $117 2021-12-16 Buy
Ambeed A168683 NU 2058 98+% 5mg $54 2021-12-16 Buy
Ambeed A168683 NU 2058 98+% 10mg $70 2021-12-16 Buy
Ambeed A168683 NU 2058 98+% 25mg $90 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001281 NU 2058 95.00% 100G $2455.22 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001281 NU 2058 95.00% 10MG $697.34 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001281 NU 2058 95.00% 50MG $1170.31 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001281 NU 2058 95.00% 5MG $435 2021-12-16 Buy
ApexBio Technology BA3824 NU2058 50mg $230 2026-05-06 Buy
ApexBio Technology BA3824 NU2058 100mg $360 2026-05-06 Buy
ApexBio Technology BA3824 NU2058 1mL(10mMinDMSO) $55 2026-05-06 Buy
ApexBio Technology BA3824 NU2058 10mg $86 2026-05-06 Buy
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Properties

Melting point :199°C(lit.)
Boiling point :424.8±55.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: 22 mg/mL
form :powder to crystal
pka :7.36±0.20(Predicted)
color :white
λmax :281nm(MeOH)(lit.)
InChI :InChI=1S/C12H17N5O/c13-12-16-10-9(14-7-15-10)11(17-12)18-6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H3,13,14,15,16,17)
InChIKey :MWGXGTJJAOZBNW-UHFFFAOYSA-N
SMILES :N1C2C(=NC(N)=NC=2OCC2CCCCC2)NC=1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NU2058, O(6)-Cyclohexylmethylguanine, has displayed the capacity to competitively inhibit CDK1 and CDK2 with respect to ATP and has also been shown to inhibit Topo II ATPase activity. Studies suggest that NU2058 also modifies p53-dependent transcription and interrupts the cell cycle causing cell growth arrest. NU2058 demonstrates the ability to alter the transport of platinum-based compounds via an increase in DNA adducts, which causes an increase in intracellular platinum levels. Further experiments reveal that growth inhibition caused by NU2058 is correlated to an increase in p27 levels, a decrease in early gene expression and CDK2 activity, as well as G1 cell cycle arrest. NU2058 is an inhibitor of cyclin A and cyclin B.

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