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ChemicalBook >> CAS DataBase List >> Flavopiridol

Flavopiridol

Flavopiridol price.
  • $51 - $2607.41
  • Product name: Flavopiridol
  • CAS: 146426-40-6
  • MF: C21H20ClNO5
  • MW: 401.84
  • EINECS:
  • MDL Number:MFCD20501884
  • Synonyms:FLAVOPIRIDOL;2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3s,4r)-3-hydroxy-1-methyl-4-piperidyl]chromen-4-one;4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-;(-)cis-5,7-Dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one;C077990;Hmr 1275;L 868275;L-868275
28 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500MG
  • 1g
  • ManufacturerAK Scientific
  • Product numberV0695
  • Product descriptionFlavopiridol
  • Packaging100mg
  • Price$896
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000100
  • Product descriptionFLAVOPIRIDOL 95.00%
  • Packaging500MG
  • Price$2607.41
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3417
  • Product descriptionFlavopiridol
  • Packaging100mg
  • Price$366
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3417
  • Product descriptionFlavopiridol
  • Packaging1g
  • Price$2299
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154639
  • Product descriptionFlavopiridol >99%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154639
  • Product descriptionFlavopiridol >99%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154639
  • Product descriptionFlavopiridol >99%
  • Packaging1g
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFF65024
  • Product descriptionFlavopiridol
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFF65024
  • Product descriptionFlavopiridol
  • Packaging50mg
  • Price$262.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number26024
  • Product descriptionFlavopiridol ≥95%
  • Packaging5mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26024
  • Product descriptionFlavopiridol ≥95%
  • Packaging25mg
  • Price$208
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26024
  • Product descriptionFlavopiridol ≥95%
  • Packaging50mg
  • Price$384
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26024
  • Product descriptionFlavopiridol ≥95%
  • Packaging100mg
  • Price$656
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018
  • Product descriptionFlavopiridol 99.72%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018
  • Product descriptionFlavopiridol 99.72%
  • Packaging10mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018
  • Product descriptionFlavopiridol 99.72%
  • Packaging50mg
  • Price$234
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific V0695 Flavopiridol 100mg $896 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000100 FLAVOPIRIDOL 95.00% 500MG $2607.41 2021-12-16 Buy
ApexBio Technology A3417 Flavopiridol 100mg $366 2021-12-16 Buy
ApexBio Technology A3417 Flavopiridol 1g $2299 2021-12-16 Buy
Biorbyt Ltd orb154639 Flavopiridol >99% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb154639 Flavopiridol >99% 250mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb154639 Flavopiridol >99% 1g $2245.7 2021-12-16 Buy
Biosynth Carbosynth FF65024 Flavopiridol 10mg $75 2021-12-16 Buy
Biosynth Carbosynth FF65024 Flavopiridol 50mg $262.5 2021-12-16 Buy
Cayman Chemical 26024 Flavopiridol ≥95% 5mg $57 2024-03-01 Buy
Cayman Chemical 26024 Flavopiridol ≥95% 25mg $208 2024-03-01 Buy
Cayman Chemical 26024 Flavopiridol ≥95% 50mg $384 2024-03-01 Buy
Cayman Chemical 26024 Flavopiridol ≥95% 100mg $656 2024-03-01 Buy
ChemScene CS-0018 Flavopiridol 99.72% 5mg $60 2021-12-16 Buy
ChemScene CS-0018 Flavopiridol 99.72% 10mg $84 2021-12-16 Buy
ChemScene CS-0018 Flavopiridol 99.72% 50mg $234 2021-12-16 Buy

Properties

Melting point :52.5 °C
Boiling point :603.6±55.0 °C(Predicted)
Density :1.448±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :insoluble in H2O; ≥40.2 mg/mL in DMSO; ≥85.4 mg/mL in EtOH with gentle warming and ultrasonic
form :Yellow powder.
pka :6.16±0.40(Predicted)
InChIKey :BIIVYFLTOXDAOV-YVEFUNNKSA-N
SMILES :C1(C2=CC=CC=C2Cl)OC2=C([C@H]3CCN(C)C[C@H]3O)C(O)=CC(O)=C2C(=O)C=1
CAS DataBase Reference :146426-40-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Flavopiridol is a synthetic flavone compound that inhibits the phosphorylation of cyclin-dependent kinases (Cdks) and suppresses expression of cyclin D1 and D3, interrupting the central role of Cdks in the regulation of the cell cycle and consequently promoting apoptosis. This action has been exploited in studies investigating the suppression of oncogenic proliferation, synovial hyperplasia, and joint destruction related to rheumatoid arthritis. Flavopiridol is an inhibitor of Cdk1, Cdk10, Cdk11, Cdk2, Cdk3, Cdk4, Cdk5, Cdk6, Cdk7, Cdk8 and Cdk9.

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