NU7026
|
- $63 - $1500
- Product name: NU7026
- CAS: 154447-35-5
- MF: C17H15NO3
- MW: 281.31
- EINECS:
- MDL Number:MFCD06798345
- Synonyms:2-MORPHOLINO-4H-BENZO[H]CHROMEN-4-ONE;NU7026, >=98%;2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one;NU7026;LY293646; NU-7026;LY 293646;2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one;4H-Naphtho[1,2-b]pyran-4-one, 2-(4-morpholinyl)-;2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one NU7026
39 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 20mg
- 25mg
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 50.00mg
- 50mg
- 100MG
- 250.00mg
- 250MG
- 1g
- Manufactureraablocks
- Product numberAA00AQ8V
- Product description2-(Morpholin-4-yl)benzo[h]chromen-4-one ≥98%
- Packaging10mg
- Price$121
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00AQ8V
- Product description2-(Morpholin-4-yl)benzo[h]chromen-4-one ≥95%
- Packaging5mg
- Price$90
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00AQ8V
- Product description2-(Morpholin-4-yl)benzo[h]chromen-4-one ≥98%
- Packaging50mg
- Price$346
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX212388
- Product descriptionNU7026 97%
- Packaging250MG
- Price$1120
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX212388
- Product descriptionNU7026 97%
- Packaging100MG
- Price$560
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY1895
- Product description2-(Morpholin-4-yl)-benzo[h]chromen-4-one
- Packaging25mg
- Price$313
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003646
- Product descriptionNU-7026 95.00%
- Packaging10MG
- Price$693.69
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003646
- Product descriptionNU-7026 95.00%
- Packaging50MG
- Price$1166.67
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003646
- Product descriptionNU-7026 95.00%
- Packaging5MG
- Price$193.6
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8649
- Product descriptionNU 7026
- Packaging10mg
- Price$75
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8649
- Product descriptionNU 7026
- Packaging50mg
- Price$320
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberCFN60301
- Product descriptionNU7026 ≥98%
- Packaging20mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-15719
- Product descriptionNU7026 99.97%
- Packaging5mg
- Price$63
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-15719
- Product descriptionNU7026 99.97%
- Packaging10mg
- Price$101
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-15719
- Product descriptionNU7026 99.97%
- Packaging50mg
- Price$361
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-15719
- Product descriptionNU7026 99.97%
- Packaging100mg
- Price$537
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00AQ8V | 2-(Morpholin-4-yl)benzo[h]chromen-4-one ≥98% | 10mg | $121 | 2026-05-28 | Buy |
| aablocks | AA00AQ8V | 2-(Morpholin-4-yl)benzo[h]chromen-4-one ≥95% | 5mg | $90 | 2026-05-28 | Buy |
| aablocks | AA00AQ8V | 2-(Morpholin-4-yl)benzo[h]chromen-4-one ≥98% | 50mg | $346 | 2026-05-28 | Buy |
| ACHEMBLOCK | X212388 | NU7026 97% | 250MG | $1120 | 2026-05-27 | Buy |
| ACHEMBLOCK | X212388 | NU7026 97% | 100MG | $560 | 2026-05-27 | Buy |
| AK Scientific | Y1895 | 2-(Morpholin-4-yl)-benzo[h]chromen-4-one | 25mg | $313 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003646 | NU-7026 95.00% | 10MG | $693.69 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003646 | NU-7026 95.00% | 50MG | $1166.67 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003646 | NU-7026 95.00% | 5MG | $193.6 | 2021-12-16 | Buy |
| ApexBio Technology | A8649 | NU 7026 | 10mg | $75 | 2026-05-06 | Buy |
| ApexBio Technology | A8649 | NU 7026 | 50mg | $320 | 2026-05-06 | Buy |
| Arctom | CFN60301 | NU7026 ≥98% | 20mg | $238 | 2021-12-16 | Buy |
| Arctom | HY-15719 | NU7026 99.97% | 5mg | $63 | 2026-05-26 | Buy |
| Arctom | HY-15719 | NU7026 99.97% | 10mg | $101 | 2026-05-26 | Buy |
| Arctom | HY-15719 | NU7026 99.97% | 50mg | $361 | 2026-05-26 | Buy |
| Arctom | HY-15719 | NU7026 99.97% | 100mg | $537 | 2026-05-26 | Buy |
Properties
Melting point :267-269 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling point :459.9±45.0 °C(Predicted)
Density :1.330
storage temp. :2-8°C
solubility :DMSO: 3 mg/mL at 60 °C, soluble
form :solid
pka :0.49±0.20(Predicted)
color :tan
InChI :1S/C17H15NO3/c19-15-11-16(18-7-9-20-10-8-18)21-17-13-4-2-1-3-12(13)5-6-14(15)17/h1-6,11H,7-10H2
InChIKey :KKTZALUTXUZPSN-UHFFFAOYSA-N
SMILES :O=C1C=C(Oc2c1ccc3ccccc23)N4CCOCC4
Boiling point :459.9±45.0 °C(Predicted)
Density :1.330
storage temp. :2-8°C
solubility :DMSO: 3 mg/mL at 60 °C, soluble
form :solid
pka :0.49±0.20(Predicted)
color :tan
InChI :1S/C17H15NO3/c19-15-11-16(18-7-9-20-10-8-18)21-17-13-4-2-1-3-12(13)5-6-14(15)17/h1-6,11H,7-10H2
InChIKey :KKTZALUTXUZPSN-UHFFFAOYSA-N
SMILES :O=C1C=C(Oc2c1ccc3ccccc23)N4CCOCC4
Safety Information
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| Signal word: | Danger | ||||||||||||||||
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Description
DNA-dependent protein kinase (DNA-PK) binds to strand breaks produced during normal cellular processes or in response to genotoxic stresses, such as ionizing radiation, targeting substrates that facilitate DNA repair. NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK (IC50 = 230 nM). It poorly inhibits phosphioinositide 3 kinase (IC50 = 13 μM) and is inactive against ataxia telangiectasia mutated kinase, ATR, and poly (ADP-ribose) polymerase. NU 7026 impairs cellular DNA double strand break repair and decreases survival in cells exposed to ionizing radiation. It also potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia. For example, it potentiates the growth inhibitory effects of mitoxantrone in K562 cells more than 10-fold.More related product prices
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