O-7460
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- $65 - $696
- Product name: O-7460
- CAS: 1572051-31-0
- MF: C25H48FO5P
- MW: 478.618
- EINECS:
- MDL Number:
- Synonyms:O-7460;ZLEFMXNNQCABDB-SEYXRHQNSA-N;1-((fluoro(methyl)phosphoryl)oxy)-3-isopropoxypropan-2-yl oleate;O7460,O 7460;9-Octadecenoic acid (9Z)-, 2-[(fluoromethylphosphinyl)oxy]-1-[(1-methylethoxy)methyl]ethyl ester
9 prices
Selected condition：
Brand
- Arctom
- Cayman Chemical
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 500g
- 5mg
- 500μg(10.45mM*100μLinMethylacetate)(Solvent)
- ManufacturerArctom
- Product numberHY-120851
- Product descriptionO-7460 95.0%
- Packaging500μg(10.45mM*100μLinMethylacetate)(Solvent)
- Price$181
- Updated2026-05-26
- Buy
- ManufacturerCayman Chemical
- Product number14009
- Product descriptionO-7460 ≥95%
- Packaging5mg
- Price$632
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14009
- Product descriptionO-7460 ≥95%
- Packaging500μg
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14009
- Product descriptionO-7460 ≥95%
- Packaging500μg
- Price$90
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number14009
- Product descriptionO-7460 ≥95%
- Packaging1mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14009
- Product descriptionO-7460 ≥95%
- Packaging1mg
- Price$168
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number14009
- Product descriptionO-7460 ≥95%
- Packaging5mg
- Price$696
- Updated2026-04-30
- Buy
- ManufacturerTRC
- Product numberO003500
- Product descriptionO-7460
- Packaging500g
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number461164
- Product descriptionO-7460
- Packaging500g
- Price$333
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Arctom | HY-120851 | O-7460 95.0% | 500μg(10.45mM*100μLinMethylacetate)(Solvent) | $181 | 2026-05-26 | Buy |
| Cayman Chemical | 14009 | O-7460 ≥95% | 5mg | $632 | 2024-03-01 | Buy |
| Cayman Chemical | 14009 | O-7460 ≥95% | 500μg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 14009 | O-7460 ≥95% | 500μg | $90 | 2026-04-30 | Buy |
| Cayman Chemical | 14009 | O-7460 ≥95% | 1mg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 14009 | O-7460 ≥95% | 1mg | $168 | 2026-04-30 | Buy |
| Cayman Chemical | 14009 | O-7460 ≥95% | 5mg | $696 | 2026-04-30 | Buy |
| TRC | O003500 | O-7460 | 500g | $65 | 2021-12-16 | Buy |
| Usbiological | 461164 | O-7460 | 500g | $333 | 2021-12-16 | Buy |
Properties
Boiling point :536.5±50.0 °C(Predicted)
Density :0.994±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Liquid
color :Colorless to light yellow
Density :0.994±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Liquid
color :Colorless to light yellow
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||||||||||||||
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Description
In humans, two forms of diacylglycerol lipase, DAGLα and DAGLβ, generate the endocannabinoid 2-arachidonoyl glycerol (2-AG; ) by attacking DAG at the sn-1 position. O-7460 is a selective inhibitor of 2-AG biosynthesis via DAGLα (IC50 = 690 nM). It demonstrates much weaker inhibition towards human monoacylglycerol lipase and rat brain fatty acid amide hydrolase (IC50s > 10 μM) and does not bind to CB1 or CB2 cannabinoid receptors (Kis > 10 μM). At 0-12 mg/kg, i.p. in mice, O-7460 was reported to dose-dependently inhibit high-fat diet intake and reduce body weight.More related product prices
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