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ChemicalBook >> CAS DataBase List >> OLIGOMYCIN

OLIGOMYCIN

OLIGOMYCIN price.
  • $32 - $1340
  • Product name: OLIGOMYCIN
  • CAS: 1404-19-9
  • MF: C135H220O33
  • MW: 2371.1715
  • EINECS:215-767-9
  • MDL Number:MFCD01779388
  • Synonyms:OLIGOMYCIN FROM STREPTOMYCES*DIASTATOCHR OMOGENE;OLIGOMYCIN, MIXTURE OF THE COMPONENTS A, B AND C;OLIGOMYCIN, MIXTURE OF A, B AND C;OligomycinABCcomplex;oligomycin from streptomyces diastatochromogenes;Nystatin dehydrate;OLIGOMYCIN, MIXTURE OF A, B AND C, FROM STREPTOMYCES DIASTATOCHROMOGENES;diastatochromogenes
18 prices
Selected condition:
Brand
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number3177BB
  • Product description(4E,5'R,6R,7S,8R,10R,11R,12S,14S,15R,16S,18E,20E,28R,29S)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3177BB
  • Product description(4E,5'R,6R,7S,8R,10R,11R,12S,14S,15R,16S,18E,20E,28R,29S)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione
  • Packaging5mg
  • Price$171
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3177BB
  • Product description(4E,5'R,6R,7S,8R,10R,11R,12S,14S,15R,16S,18E,20E,28R,29S)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione
  • Packaging10mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61898
  • Product descriptionOligomycin
  • Packaging1mg
  • Price$48.4
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61898
  • Product descriptionOligomycin
  • Packaging10mg
  • Price$270
  • Updated2024-03-01
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3007
  • Product descriptionOligomycinComplex
  • Packaging5mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3007
  • Product descriptionOligomycinComplex
  • Packaging10mg
  • Price$129
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number11341
  • Product descriptionOligomycin Complex
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number11341
  • Product descriptionOligomycin Complex ≥95% (Mixture of A, B, C)
  • Packaging5mg
  • Price$66
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number11341
  • Product descriptionOligomycin Complex ≥95% (Mixture of A, B, C)
  • Packaging10mg
  • Price$115
  • Updated2024-03-01
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  • ManufacturerChemScene
  • Product numberCS-0003801
  • Product descriptionOligomycin ≥98.0%
  • Packaging10mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberO4876
  • Product descriptionOligomycin from Streptomyces diastatochromogenes ≥95% total oligomycins basis (HPLC)
  • Packaging5mg
  • Price$99.6
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number495455
  • Product descriptionOligomycin
  • Packaging10mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberO4876
  • Product descriptionOligomycin from Streptomyces diastatochromogenes ≥95% total oligomycins basis (HPLC)
  • Packaging25mg
  • Price$400
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberO4876
  • Product descriptionOligomycin from Streptomyces diastatochromogenes ≥95% total oligomycins basis (HPLC)
  • Packaging250mg
  • Price$972
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberO4876
  • Product descriptionOligomycin from Streptomyces diastatochromogenes ≥95% total oligomycins basis (HPLC)
  • Packaging100mg
  • Price$1340
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3177BB (4E,5'R,6R,7S,8R,10R,11R,12S,14S,15R,16S,18E,20E,28R,29S)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione 1mg $133 2021-12-16 Buy
AK Scientific 3177BB (4E,5'R,6R,7S,8R,10R,11R,12S,14S,15R,16S,18E,20E,28R,29S)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione 5mg $171 2021-12-16 Buy
AK Scientific 3177BB (4E,5'R,6R,7S,8R,10R,11R,12S,14S,15R,16S,18E,20E,28R,29S)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione 10mg $225 2021-12-16 Buy
Alfa Aesar J61898 Oligomycin 1mg $48.4 2023-06-20 Buy
Alfa Aesar J61898 Oligomycin 10mg $270 2024-03-01 Buy
ApexBio Technology C3007 OligomycinComplex 5mg $68 2021-12-16 Buy
ApexBio Technology C3007 OligomycinComplex 10mg $129 2021-12-16 Buy
Cayman Chemical 11341 Oligomycin Complex 1mg $32 2024-03-01 Buy
Cayman Chemical 11341 Oligomycin Complex ≥95% (Mixture of A, B, C) 5mg $66 2024-03-01 Buy
Cayman Chemical 11341 Oligomycin Complex ≥95% (Mixture of A, B, C) 10mg $115 2024-03-01 Buy
ChemScene CS-0003801 Oligomycin ≥98.0% 10mg $220 2021-12-16 Buy
Sigma-Aldrich O4876 Oligomycin from Streptomyces diastatochromogenes ≥95% total oligomycins basis (HPLC) 5mg $99.6 2024-03-01 Buy
Sigma-Aldrich 495455 Oligomycin 10mg $130 2024-03-01 Buy
Sigma-Aldrich O4876 Oligomycin from Streptomyces diastatochromogenes ≥95% total oligomycins basis (HPLC) 25mg $400 2024-03-01 Buy
Sigma-Aldrich O4876 Oligomycin from Streptomyces diastatochromogenes ≥95% total oligomycins basis (HPLC) 250mg $972 2024-03-01 Buy
Sigma-Aldrich O4876 Oligomycin from Streptomyces diastatochromogenes ≥95% total oligomycins basis (HPLC) 100mg $1340 2024-03-01 Buy

Properties

Melting point :84-100 °C
Density :1.143 g/cm3
storage temp. :−20°C
solubility :Soluble in DMSO (up to 300 mg/ml) or in Ethanol (up to 200 mg/ml)
form :White solid
color :White
Water Solubility :Sparingly soluble in water. Soluble in DMSO (20mg/ml) and ethanol (30mg/ml) /n
BRN :7615308
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P330 Rinse mouth.

Description

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases. The mitochondrial F1FO ATP synthase can switch to an ATP hydrolase during ischemia, so that, under these conditions, inhibition by oligomycins will reduce ATP depletion rather than block ATP synthesis. Oligomycin complex is a mixture of oligomycins A , B , and C. Oligomycin A is a selective inhibitor of mitochondrial F1FO-ATP synthase that induces apoptosis in a variety of cell types (average GI50 = 270 nM). Oligomycin B is a nonselective inhibitor of ATP synthases. Oligomycin B (1-10 μM) can reduce the rate of ATP depletion in myocardial ischemia and decrease calcium-induced calcium release oscillation frequency of rat sensory neurons.