ONO-8130
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- $43 - $3405
- Product name: ONO-8130
- CAS: 459841-96-4
- MF: C25H28N2O5S2
- MW: 500.63
- EINECS:
- MDL Number:
- Synonyms:ONO-8130;4-[[[2,3-Dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-indene-5yl]oxy]methyl]benzoic acid;Orally active,ONO8130,Inhibitor,inhibit,Bladder pain,ONO 8130,Prostaglandin Receptor,Interstitial cystitis,PKR-like endoplasmic reticulum kinase,PERK,Hyperalgesia,Protein kinase R-like endoplasmic reticulum kinase,ONO-8130;Benzoic acid, 4-[[[2,3-dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-inden-5-yl]oxy]methyl]-;ONO-8130, 10 mM in DMSO
29 prices
Selected condition:
Brand
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- DC Chemicals
- Tocris
- TRC
Package
- 1mg
- 10mM*1mLinDMSO
- 50
- 5MG
- 10
- 10mg
- 25MG
- 100MG
- 250mg
- 1g
- ManufacturerACHEMBLOCK
- Product numberU127719
- Product description4-(((6-((N-isobutyl-4-methylthiazole)-2-sulfonamido)-2,3-dihydro-1H-inden-5-yl)oxy)methyl)benzoic acid 98%
- Packaging5MG
- Price$430
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127719
- Product description4-(((6-((N-isobutyl-4-methylthiazole)-2-sulfonamido)-2,3-dihydro-1H-inden-5-yl)oxy)methyl)benzoic acid 98%
- Packaging25MG
- Price$1135
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127719
- Product description4-(((6-((N-isobutyl-4-methylthiazole)-2-sulfonamido)-2,3-dihydro-1H-inden-5-yl)oxy)methyl)benzoic acid 98%
- Packaging100MG
- Price$3405
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3396CR
- Product description4-[[6-[2-Methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]oxymethyl]benzoicacid
- Packaging25mg
- Price$788
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3396CR
- Product description4-[[6-[2-Methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]oxymethyl]benzoicacid
- Packaging1mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5743
- Product descriptionONO-8130
- Packaging5mg
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5743
- Product descriptionONO-8130
- Packaging5mg
- Price$249
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC5743
- Product descriptionONO-8130
- Packaging10mg
- Price$291
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5743
- Product descriptionONO-8130
- Packaging10mg
- Price$388
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC5743
- Product descriptionONO-8130
- Packaging25mg
- Price$903
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC5743
- Product descriptionONO-8130
- Packaging25mg
- Price$677
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19118
- Product descriptionONO-8130 ≥98%
- Packaging25mg
- Price$684
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number19118
- Product descriptionONO-8130 ≥98%
- Packaging10mg
- Price$270
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19118
- Product descriptionONO-8130 ≥98%
- Packaging10mg
- Price$297
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number19118
- Product descriptionONO-8130 ≥98%
- Packaging25mg
- Price$621
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19118
- Product descriptionONO-8130 ≥98%
- Packaging5mg
- Price$196
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | U127719 | 4-(((6-((N-isobutyl-4-methylthiazole)-2-sulfonamido)-2,3-dihydro-1H-inden-5-yl)oxy)methyl)benzoic acid 98% | 5MG | $430 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127719 | 4-(((6-((N-isobutyl-4-methylthiazole)-2-sulfonamido)-2,3-dihydro-1H-inden-5-yl)oxy)methyl)benzoic acid 98% | 25MG | $1135 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127719 | 4-(((6-((N-isobutyl-4-methylthiazole)-2-sulfonamido)-2,3-dihydro-1H-inden-5-yl)oxy)methyl)benzoic acid 98% | 100MG | $3405 | 2026-05-27 | Buy |
| AK Scientific | 3396CR | 4-[[6-[2-Methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]oxymethyl]benzoicacid | 25mg | $788 | 2021-12-16 | Buy |
| AK Scientific | 3396CR | 4-[[6-[2-Methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]oxymethyl]benzoicacid | 1mg | $145 | 2021-12-16 | Buy |
| ApexBio Technology | C5743 | ONO-8130 | 5mg | $187 | 2021-12-16 | Buy |
| ApexBio Technology | C5743 | ONO-8130 | 5mg | $249 | 2026-05-06 | Buy |
| ApexBio Technology | C5743 | ONO-8130 | 10mg | $291 | 2021-12-16 | Buy |
| ApexBio Technology | C5743 | ONO-8130 | 10mg | $388 | 2026-05-06 | Buy |
| ApexBio Technology | C5743 | ONO-8130 | 25mg | $903 | 2026-05-06 | Buy |
| ApexBio Technology | C5743 | ONO-8130 | 25mg | $677 | 2021-12-16 | Buy |
| Cayman Chemical | 19118 | ONO-8130 ≥98% | 25mg | $684 | 2026-04-30 | Buy |
| Cayman Chemical | 19118 | ONO-8130 ≥98% | 10mg | $270 | 2024-03-01 | Buy |
| Cayman Chemical | 19118 | ONO-8130 ≥98% | 10mg | $297 | 2026-04-30 | Buy |
| Cayman Chemical | 19118 | ONO-8130 ≥98% | 25mg | $621 | 2024-03-01 | Buy |
| Cayman Chemical | 19118 | ONO-8130 ≥98% | 5mg | $196 | 2026-04-30 | Buy |
Properties
Boiling point :705.1±70.0 °C(Predicted)
Density :1.344±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤2mg/ml in ethanol;3mg/ml in DMSO;1mg/ml in dimethyl formamide
form :crystalline solid
pka :4.17±0.10(Predicted)
Density :1.344±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤2mg/ml in ethanol;3mg/ml in DMSO;1mg/ml in dimethyl formamide
form :crystalline solid
pka :4.17±0.10(Predicted)
Safety Information
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Description
ONO-8130 is an orally bioavailable antagonist of the prostaglandin E2 (PGE2) receptor EP (Ki = 1.9 nM) It exerts a more than 1,000-fold selectivity for EP1 compared with other EP receptors. ONO-8130 suppresses pain associated with cyclophosphamide-induced cystitis in mice at 0.3-30 mg/kg. It also blocks PGE2-induced contraction and eliminates spontaneous tone of guinea pig trachea tested in tissue organ baths.Suppliers and manufacturers
Wuhan Topule Biopharmaceutical Co., Ltd
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
NANJING YINGWEN BIOTECHNOLOGY CO LTD
Shanghai EFE Biological Technology Co., Ltd.
BOC Sciences
Changzhou Chenhong Biotechnology Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.




