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ChemicalBook >> CAS DataBase List >> OPHIOBOLIN B

OPHIOBOLIN B

OPHIOBOLIN B price.
  • $265 - $1306
  • Product name: OPHIOBOLIN B
  • CAS: 5601-74-1
  • MF: C25H38O4
  • MW: 402.57
  • EINECS:
  • MDL Number:MFCD08061872
  • Synonyms:OPHIOBOLIN B;3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al;Cochliobolin B;Cochliobolin B, Zizanin B, Ophiobolsin A;Dicyclopenta[a,d]cyclooctene-4-carboxaldehyde, 7-[(1S)-1,5-dimethyl-4-hexen-1-yl]-1,2,3,3a,6,6a,7,8,9,9a,10,10a-dodecahydro-1,7-dihydroxy-1,9a-dimethyl-3-oxo-, (1R,3aS,6aR,7S,9aR,10aS)-;Ophiobolin B (Cochliobolin B)
8 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number5200CT
  • Product descriptionOphiobolinB
  • Packaging5mg
  • Price$1306
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3839
  • Product descriptionOphiobolinB
  • Packaging1mg
  • Price$381
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3839
  • Product descriptionOphiobolinB
  • Packaging5mg
  • Price$1239
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18432
  • Product descriptionOphiobolin B ≥95%
  • Packaging1mg
  • Price$335
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18432
  • Product descriptionOphiobolin B ≥95%
  • Packaging5mg
  • Price$1085
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberO669205
  • Product descriptionOphiobolinB
  • Packaging1mg
  • Price$265
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberO7024-01
  • Product descriptionOphiobolin B
  • Packaging1mg
  • Price$523
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number461592
  • Product descriptionOphiobolin B
  • Packaging1mg
  • Price$602
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5200CT OphiobolinB 5mg $1306 2021-12-16 Buy
ApexBio Technology C3839 OphiobolinB 1mg $381 2021-12-16 Buy
ApexBio Technology C3839 OphiobolinB 5mg $1239 2021-12-16 Buy
Cayman Chemical 18432 Ophiobolin B ≥95% 1mg $335 2024-03-01 Buy
Cayman Chemical 18432 Ophiobolin B ≥95% 5mg $1085 2024-03-01 Buy
TRC O669205 OphiobolinB 1mg $265 2021-12-16 Buy
Usbiological O7024-01 Ophiobolin B 1mg $523 2021-12-16 Buy
Usbiological 461592 Ophiobolin B 1mg $602 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form :White to off-white solid.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Calmodulin is a calcium-sensing protein that regulates a wide array of proteins involved in diverse cellular functions. Ophiobolin B is a sesterterpenoid fungal phytotoxin that binds and irreversibly antagonizes calmodulin, producing cytotoxic and antimicrobial effects. It induces apoptosis in chronic lymphocytic leukemia cells with an LC50 value of 2 nM and in different zygomycetes with MIC values ranging from 25-50 μg/ml.

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