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ChemicalBook >> CAS DataBase List >> PD 168077 MALEATE

PD 168077 MALEATE

$93 - $5053
Product name: PD 168077 MALEATE
CAS: 630117-19-0
MF: C24H26N4O5
MW: 450.49
EINECS:
MDL Number:MFCD01321067
Synonyms:N-(METHYL-4-(2-CYANOPHENYL)PIPERAZINYL)-3-METHYLBENZAMIDE MALEATE;PD 168077 MALEATE;N-[[4-(2-CYANOPHENYL)-1-PIPERAZINYL]METHYL]-3-METHYL-BENZAMIDE MALEATE;PD 168077 (maL;Benzamide,N-[[4-(2-cyanophenyl)-1-piperazinyl]methyl]-3-methyl-,(2Z)-2-butenedioate(1:1);PD 168077,Dopamine Receptor,PD-168077,inhibit,PD168077,PD168077 maleate,Inhibitor,PD 168077 maleate;PD-168077 maleate, 10 mM in DMSO

Price28 Properties Safety Information Description

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Brand

Ambeed
ApexBio Technology
Biorbyt Ltd
Cayman Chemical
ChemScene
DC Chemicals
Sigma-Aldrich
Tocris
Usbiological

Package

50
5mg
10
10mg
25mg
50mg
100mg
250mg
1g

ManufacturerAmbeed
Product numberA447591
Product descriptionN-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%
Packaging5mg
Price$285
Updated2021-12-16
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ManufacturerAmbeed
Product numberA447591
Product descriptionN-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%
Packaging10mg
Price$370
Updated2021-12-16
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ManufacturerAmbeed
Product numberA447591
Product descriptionN-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%
Packaging25mg
Price$480
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA447591
Product descriptionN-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%
Packaging50mg
Price$624
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA447591
Product descriptionN-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%
Packaging100mg
Price$810
Updated2021-12-16
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ManufacturerAmbeed
Product numberA447591
Product descriptionN-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%
Packaging1g
Price$5053
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB6578
Product descriptionPD168077maleate
Packaging5mg
Price$158
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB6578
Product descriptionPD168077maleate
Packaging10mg
Price$236
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB6578
Product descriptionPD168077maleate
Packaging25mg
Price$488
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB6578
Product descriptionPD168077maleate
Packaging50mg
Price$819
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB6578
Product descriptionPD168077maleate
Packaging100mg
Price$1386
Updated2021-12-16
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ManufacturerBiorbyt Ltd
Product numberorb572969
Product descriptionPD-168077 maleate >98%
Packaging100mg
Price$838.1
Updated2021-12-16
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ManufacturerBiorbyt Ltd
Product numberorb572969
Product descriptionPD-168077 maleate >98%
Packaging250mg
Price$1654.1
Updated2021-12-16
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ManufacturerBiorbyt Ltd
Product numberorb572969
Product descriptionPD-168077 maleate >98%
Packaging1g
Price$3282.7
Updated2021-12-16
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ManufacturerCayman Chemical
Product number29789
Product descriptionPD 168077 (maleate)
Packaging5mg
Price$93
Updated2024-03-01
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ManufacturerCayman Chemical
Product number29789
Product descriptionPD 168077 (maleate)
Packaging10mg
Price$166
Updated2024-03-01
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Ambeed	A447591	N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%	5mg	$285	2021-12-16	Buy
Ambeed	A447591	N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%	10mg	$370	2021-12-16	Buy
Ambeed	A447591	N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%	25mg	$480	2021-12-16	Buy
Ambeed	A447591	N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%	50mg	$624	2021-12-16	Buy
Ambeed	A447591	N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%	100mg	$810	2021-12-16	Buy
Ambeed	A447591	N-((4-(2-Cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamidemaleate 95+%	1g	$5053	2021-12-16	Buy
ApexBio Technology	B6578	PD168077maleate	5mg	$158	2021-12-16	Buy
ApexBio Technology	B6578	PD168077maleate	10mg	$236	2021-12-16	Buy
ApexBio Technology	B6578	PD168077maleate	25mg	$488	2021-12-16	Buy
ApexBio Technology	B6578	PD168077maleate	50mg	$819	2021-12-16	Buy
ApexBio Technology	B6578	PD168077maleate	100mg	$1386	2021-12-16	Buy
Biorbyt Ltd	orb572969	PD-168077 maleate >98%	100mg	$838.1	2021-12-16	Buy
Biorbyt Ltd	orb572969	PD-168077 maleate >98%	250mg	$1654.1	2021-12-16	Buy
Biorbyt Ltd	orb572969	PD-168077 maleate >98%	1g	$3282.7	2021-12-16	Buy
Cayman Chemical	29789	PD 168077 (maleate)	5mg	$93	2024-03-01	Buy
Cayman Chemical	29789	PD 168077 (maleate)	10mg	$166	2024-03-01	Buy

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Properties

storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: >10 mg/mL
form :powder
color :white

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning		P264, P270, P301+P312, P330, P501

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PD 168077 is a dopamine D₄ receptor agonist (K_i = 8.7 nM in CHO Pro 5 cells expressing the human receptor). It is selective for dopamine D₄ over D₂ and D₃ receptors (K_is = 3,740 and 2,810 nM, respectively), as well as α₁- and α₂-adrenergic and serotonin (5-HT) receptor subtypes 5-HT_1A and 5-HT_2A (K_is = 168, 177, 385, and 4,010 nM, respectively). PD 168077 (20 μM) induces CaMKII translocation from the dendritic shaft to postsynaptic sites on the dendritic processes of primary rat embryonic prefrontal cortex pyramidal neurons, an effect that can be blocked by the IP₃ receptor antagonist 2APB or the calcium chelator BAPTA AM . PD 168077 (50-200 ng/animal) induces penile erections in rats when injected into the paraventricular nucleus (PVN) of the hypothalamus. PD 168077 (0.2-25 mg/kg, s.c.) increases spontaneous locomotor activity and reduces grooming and rearing in rats.

Suppliers and manufacturers

TargetMol Chemicals Inc.

$48.00 /5mg
PD-168077 maleate CAS:630117-19-0

ATK CHEMICAL COMPANY LIMITED

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

Zhejiang J&C Biological Technology Co.,Limited

InvivoChem

TargetMol Chemicals Inc.

Aladdin Scientific

Amadis Chemical Company Limited 3B Pharmachem (Wuhan) International Co.,Ltd. EMMX Biotechnology LLC

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