PD 184161
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- $31 - $2100
- Product name: PD 184161
- CAS: 212631-67-9
- MF: C17H13BrClF2IN2O2
- MW: 557.56
- EINECS:
- MDL Number:MFCD16038897
- Synonyms:PD 184161;PF-1529483;PF-3011370;UK-287074;MEK1/2 Inhibitor IV ;5-BroMo-2-[(2-chloro-4-iodophenyl)aMino]-N-(cyclopropylMethoxy)-3,4-difluorobenzaMide;MEK1/2 Inhibitor IV - CAS 212631-67-9 - Calbiochem;Benzamide, 5-bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-
48 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO(Solution)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- Manufactureraablocks
- Product numberAA006XZ9
- Product description5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide
- Packaging2mg
- Price$56
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006XZ9
- Product description5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide
- Packaging5mg
- Price$78
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006XZ9
- Product description5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide ≥98%
- Packaging1mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006XZ9
- Product description5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide
- Packaging10mg
- Price$123
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006XZ9
- Product description5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide
- Packaging25mg
- Price$250
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006XZ9
- Product description5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide
- Packaging50mg
- Price$403
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006XZ9
- Product description5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide
- Packaging100mg
- Price$571
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006XZ9
- Product description5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide
- Packaging200mg
- Price$810
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA006XZ9
- Product description5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide
- Packaging500mg
- Price$1204
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberT91803
- Product descriptionPD 184161 98%
- Packaging100MG
- Price$530
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT91803
- Product descriptionPD 184161 98%
- Packaging25MG
- Price$205
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3775BB
- Product description5-Bromo-2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
- Packaging1mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4361
- Product descriptionPD 184161
- Packaging5mg
- Price$115
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4361
- Product descriptionPD 184161
- Packaging10mg
- Price$205
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4361
- Product descriptionPD 184161
- Packaging25mg
- Price$450
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-10174
- Product descriptionPD184161 98.08%
- Packaging50mg
- Price$551
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA006XZ9 | 5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide | 2mg | $56 | 2026-05-28 | Buy |
| aablocks | AA006XZ9 | 5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide | 5mg | $78 | 2026-05-28 | Buy |
| aablocks | AA006XZ9 | 5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide ≥98% | 1mg | $31 | 2026-05-28 | Buy |
| aablocks | AA006XZ9 | 5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide | 10mg | $123 | 2026-05-28 | Buy |
| aablocks | AA006XZ9 | 5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide | 25mg | $250 | 2026-05-28 | Buy |
| aablocks | AA006XZ9 | 5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide | 50mg | $403 | 2026-05-28 | Buy |
| aablocks | AA006XZ9 | 5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide | 100mg | $571 | 2026-05-28 | Buy |
| aablocks | AA006XZ9 | 5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide | 200mg | $810 | 2026-05-28 | Buy |
| aablocks | AA006XZ9 | 5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide | 500mg | $1204 | 2026-05-28 | Buy |
| ACHEMBLOCK | T91803 | PD 184161 98% | 100MG | $530 | 2026-05-27 | Buy |
| ACHEMBLOCK | T91803 | PD 184161 98% | 25MG | $205 | 2026-05-27 | Buy |
| AK Scientific | 3775BB | 5-Bromo-2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide | 1mg | $128 | 2021-12-16 | Buy |
| ApexBio Technology | C4361 | PD 184161 | 5mg | $115 | 2026-05-06 | Buy |
| ApexBio Technology | C4361 | PD 184161 | 10mg | $205 | 2026-05-06 | Buy |
| ApexBio Technology | C4361 | PD 184161 | 25mg | $450 | 2026-05-06 | Buy |
| Arctom | HY-10174 | PD184161 98.08% | 50mg | $551 | 2026-05-26 | Buy |
Properties
Melting point :174-175 °C
Density :1.922±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :-6.25±0.50(Predicted)
form :White solid
color :white to off-white
InChI :1S/C17H13BrClF2IN2O2/c18-11-6-10(17(25)24-26-7-8-1-2-8)16(15(21)14(11)20)23-13-4-3-9(22)5-12(13)19/h3-6,8,23H,1-2,7H2,(H,24,25)
InChIKey :VJNZMSLGVUSPCF-UHFFFAOYSA-N
SMILES :Ic1cc(c(cc1)Nc2c(c(c(cc2C(=O)NOCC3CC3)Br)F)F)Cl
Density :1.922±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :-6.25±0.50(Predicted)
form :White solid
color :white to off-white
InChI :1S/C17H13BrClF2IN2O2/c18-11-6-10(17(25)24-26-7-8-1-2-8)16(15(21)14(11)20)23-13-4-3-9(22)5-12(13)19/h3-6,8,23H,1-2,7H2,(H,24,25)
InChIKey :VJNZMSLGVUSPCF-UHFFFAOYSA-N
SMILES :Ic1cc(c(cc1)Nc2c(c(c(cc2C(=O)NOCC3CC3)Br)F)F)Cl
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
PD 184161 is a strong and selective inhibitor of MEK-1 and MEK-2 with an IC50 value that ranges from 10-100 nM. 1 More effective at inhibiting phosphorylation of ERK1/2 than the selective MEK inhibitors, PD098059 and U0126. PD 184161 is structurally related to clinically-studied MEK inhibitors PD184352 (CI-1040) and PD 325901 and has been shown to inhibit cell proliferation, induce apoptosis, and possess anti-tumor activity in MEK-dependent cancers.More related product prices
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