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ChemicalBook >> CAS DataBase List >> PF-04929113

PF-04929113

PF-04929113 price.
  • $10 - $7000
  • Product name: PF-04929113
  • CAS: 908115-27-5
  • MF: C25H30F3N5O4
  • MW: 521.53
  • EINECS:
  • MDL Number:MFCD20526334
  • Synonyms:(1r,4r)-4-(2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl)phenylamino)cyclohexyl 2-aminoacetate;PF-04929113, >=98%;snx54227;PF04929113 SNX-54227;PF-04929113;PF-04929113(SNX5422);Glycine trans-4-[[2-(aminocarbonyl)-5-[4,5,6,7-tetrahydro-6,6-dimethyl-4-oxo-3-(trifluoromethyl)-1H-indazol-1-yl]phenyl]amino]cyclohexyl ester;CS-33
Price59 Properties Safety Information Description
59 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Labseeker
  • TRC
  • Usbiological
Package
  • 1mg
  • 10mg
  • 5mg
  • 10mM(in1mLDMSO)
  • 50mg
  • 10mM*1mLinDMSO
  • 25mg
  • 100MG
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 10g
  • Manufactureraablocks
  • Product numberAA00H0R3
  • Product descriptiontrans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate ≥98%
  • Packaging25mg
  • Price$74
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00H0R3
  • Product descriptiontrans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate ≥98%
  • Packaging50mg
  • Price$132
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00H0R3
  • Product descriptiontrans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate 98%
  • Packaging1g
  • Price$2197
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00H0R3
  • Product descriptiontrans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate ≥98%
  • Packaging10mg
  • Price$34
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00H0R3
  • Product descriptiontrans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate ≥98%
  • Packaging5mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00H0R3
  • Product descriptiontrans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate ≥98%
  • Packaging1mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY228761
  • Product descriptionPF04929113 97.00%
  • Packaging25MG
  • Price$145
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY228761
  • Product descriptionPF04929113 97.00%
  • Packaging100MG
  • Price$435
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7589
  • Product description(1r,4r)-4-((2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl2-aminoacetate
  • Packaging10mg
  • Price$434
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX7589
  • Product description(1r,4r)-4-((2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl2-aminoacetate
  • Packaging50mg
  • Price$1396
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008143
  • Product descriptionPF-04929113 95.00%
  • Packaging10MG
  • Price$644.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008143
  • Product descriptionPF-04929113 95.00%
  • Packaging5MG
  • Price$501.11
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4065
  • Product descriptionPF-04929113 (SNX-5422)
  • Packaging50mg
  • Price$455
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4065
  • Product descriptionPF-04929113(SNX-5422)
  • Packaging50mg
  • Price$690
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4065
  • Product descriptionPF-04929113 (SNX-5422)
  • Packaging100mg
  • Price$779
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4065
  • Product descriptionPF-04929113 (SNX-5422)
  • Packaging5mg
  • Price$109
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00H0R3 trans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate ≥98% 25mg $74 2026-05-28 Buy
aablocks AA00H0R3 trans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate ≥98% 50mg $132 2026-05-28 Buy
aablocks AA00H0R3 trans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate 98% 1g $2197 2026-05-28 Buy
aablocks AA00H0R3 trans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate ≥98% 10mg $34 2026-05-28 Buy
aablocks AA00H0R3 trans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate ≥98% 5mg $19 2026-05-28 Buy
aablocks AA00H0R3 trans-4-([2-(Aminocarbonyl)-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] phenyl]amino)cyclohexyl glycinate ≥98% 1mg $10 2026-05-28 Buy
ACHEMBLOCK Y228761 PF04929113 97.00% 25MG $145 2026-05-27 Buy
ACHEMBLOCK Y228761 PF04929113 97.00% 100MG $435 2026-05-27 Buy
AK Scientific X7589 (1r,4r)-4-((2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl2-aminoacetate 10mg $434 2021-12-16 Buy
AK Scientific X7589 (1r,4r)-4-((2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl2-aminoacetate 50mg $1396 2021-12-16 Buy
American Custom Chemicals Corporation API0008143 PF-04929113 95.00% 10MG $644.7 2021-12-16 Buy
American Custom Chemicals Corporation API0008143 PF-04929113 95.00% 5MG $501.11 2021-12-16 Buy
ApexBio Technology A4065 PF-04929113 (SNX-5422) 50mg $455 2026-05-06 Buy
ApexBio Technology A4065 PF-04929113(SNX-5422) 50mg $690 2021-12-16 Buy
ApexBio Technology A4065 PF-04929113 (SNX-5422) 100mg $779 2026-05-06 Buy
ApexBio Technology A4065 PF-04929113 (SNX-5422) 5mg $109 2026-05-06 Buy
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Properties

Melting point :298-299℃
Boiling point :646.5±55.0 °C(Predicted)
Density :1.48
storage temp. :Store at -20°C
solubility :≥23.85 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form :solid
pka :15.07±0.50(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PF-04929113 is a prodrug for the Hsp90 inhibitor, PF-04958473 (SNX-2112), which binds both Hsp90α and Hsp90β with an IC50 value of 30 nM. The prodrug, PF-04929113, is rapidly absorbed and converted into the active inhibitor after oral administration. The active inhibitor causes degradation of Hsp90 client proteins, including HER2, and reduces phosphorylation of downstream kinases, including Akt and ERK1/2, leading to apoptosis in cancer cells. Oral administration of the prodrug, PF-04929113, reduces tumor growth and prolongs survival in mouse models of multiple myeloma and prostate cancer.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
PF04929113
$33.00
PF04929113 CAS:908115-27-5
ATK CHEMICAL COMPANY LIMITED
Career Henan Chemica Co
Dideu Industries Group Limited
Shenzhen Shengda Pharma Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
HANGZHOU LEAP CHEM CO., LTD.