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ChemicalBook >> CAS DataBase List >> PF-9184

PF-9184

PF-9184 price.
  • $44 - $1718
  • Product name: PF-9184
  • CAS: 1221971-47-6
  • MF: C21H14Cl2N2O4S
  • MW: 461.32
  • EINECS:
  • MDL Number:
  • Synonyms:PF-9184;N-[3',4'-Dichloro(1,1'-biphenyl)-yl]-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide;PF-03549184;2H-1,2-Benzothiazine-3-carboxamide, N-(3',4'-dichloro[1,1'-biphenyl]-4-yl)-4-hydroxy-, 1,1-dioxide;PF9184,PF 9184;N-(3',4'-dichloro-[1,1'-biphenyl]-4-yl)-4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide
Price29 Properties Safety Information Description
29 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
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  • 1mg
  • 5mg
  • 50
  • 10mg
  • 25MG
  • 50mg
  • 100MG
  • Manufactureraablocks
  • Product numberAA00A161
  • Product descriptionPF-9184
  • Packaging1mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00A161
  • Product descriptionPF-9184
  • Packaging5mg
  • Price$76
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00A161
  • Product descriptionPF-9184
  • Packaging10mg
  • Price$104
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227175
  • Product descriptionPF-9184 97.00%
  • Packaging25MG
  • Price$310
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227175
  • Product descriptionPF-9184 97.00%
  • Packaging100MG
  • Price$805
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2750DM
  • Product descriptionN-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide
  • Packaging10mg
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2750DM
  • Product descriptionN-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2750DM
  • Product descriptionN-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide
  • Packaging5mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3475
  • Product descriptionPF-9184
  • Packaging10mg
  • Price$228
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3475
  • Product descriptionPF-9184
  • Packaging5mg
  • Price$164
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3475
  • Product descriptionPF-9184
  • Packaging25mg
  • Price$487
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-19622
  • Product descriptionPF-9184 98.10%
  • Packaging50mg
  • Price$414
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19622
  • Product descriptionPF-9184 98.10%
  • Packaging25mg
  • Price$257
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19622
  • Product descriptionPF-9184 98.10%
  • Packaging10mg
  • Price$143
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-19622
  • Product descriptionPF-9184 98.10%
  • Packaging5mg
  • Price$86
  • Updated2026-05-26
  • Buy
  • ManufacturerBiosynth
  • Product numberWYB97147
  • Product descriptionPF-03549184
  • Packaging50mg
  • Price$1718
  • Updated2026-06-05
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00A161 PF-9184 1mg $44 2026-05-28 Buy
aablocks AA00A161 PF-9184 5mg $76 2026-05-28 Buy
aablocks AA00A161 PF-9184 10mg $104 2026-05-28 Buy
ACHEMBLOCK Y227175 PF-9184 97.00% 25MG $310 2026-05-27 Buy
ACHEMBLOCK Y227175 PF-9184 97.00% 100MG $805 2026-05-27 Buy
AK Scientific 2750DM N-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide 10mg $266 2021-12-16 Buy
AK Scientific 2750DM N-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide 1mg $147 2021-12-16 Buy
AK Scientific 2750DM N-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide 5mg $218 2021-12-16 Buy
ApexBio Technology C3475 PF-9184 10mg $228 2026-05-06 Buy
ApexBio Technology C3475 PF-9184 5mg $164 2026-05-06 Buy
ApexBio Technology C3475 PF-9184 25mg $487 2026-05-06 Buy
Arctom HY-19622 PF-9184 98.10% 50mg $414 2026-05-26 Buy
Arctom HY-19622 PF-9184 98.10% 25mg $257 2026-05-26 Buy
Arctom HY-19622 PF-9184 98.10% 10mg $143 2026-05-26 Buy
Arctom HY-19622 PF-9184 98.10% 5mg $86 2026-05-26 Buy
Biosynth WYB97147 PF-03549184 50mg $1718 2026-06-05 Buy
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Properties

Melting point :285.5-289.3 °C
Density :1.574±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≤15mg/ml in DMSO;20mg/ml in dimethyl formamide
pka :4.50±1.00(Predicted)
form :powder
color :white to beige
InChI :1S/C21H14Cl2N2O4S/c22-16-10-7-13(11-17(16)23)12-5-8-14(9-6-12)25-19(21(24)27)20(26)15-3-1-2-4-18(15)30(25,28)29/h1-11,26H,(H2,24,27)
InChIKey :YGTUCAUHSJOJCQ-UHFFFAOYSA-N

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Microsomal prostaglandin E synthase-1 (mPGES-1) converts the COX product prostaglandin H2 (PGH2; ) into the biologically active PGE2 . Like COX-2, the expression of mPGES-1 is induced in response to pro-inflammatory mediators, including LPS, IL-1β, and TNF-α. PF-9184 is a potent inhibitor of mPGES-1 (IC50 = 16.5 nM for recombinant human enzyme). It displays at least 6,500-fold selectivity for mPGES-1 over COX-1 and COX-2. PF-9184 blocks the synthesis of PGE2 in LPS-treated human whole blood and in IL-1β-stimulated fibroblasts (IC50s = 0.4-5 μM).

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Suppliers and manufacturers

TargetMol Chemicals Inc.
PF-9184
PF-9184 CAS:1221971-47-6
BOC Sciences Guangzhou Isun Pharmaceutical Co., Ltd Pharmacodia (Beijing) Co.,Ltd Shanghai EFE Biological Technology Co., Ltd. Beijing Solarbio Science & Tecnology Co., Ltd. Amadis Chemical Company Limited Lynnchem Novachemistry HANGZHOU CLAP TECHNOLOGY CO.,LTD