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ChemicalBook >> Polymyxin Ile-B1

Polymyxin Ile-B1

Polymyxin Ile-B1 price.
  • $98 - $351
  • Product name: Polymyxin Ile-B1
  • CAS: 80469-10-9
  • MF: C56H98N16O13
  • MW: 1203.48
  • EINECS:
  • MDL Number:
  • Synonyms:(-)-N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Phe-L-Ile-L-A2bu-L-A2bu-L-Thr-);N2-(6-Methyloctanoyl-L-A2bu-L-Thr-L-A2bu-)cyclo(L-A2bu*-L-A2bu-D-Phe-L-Ile-L-A2bu-L-A2bu-L-Thr-);Polymyxin II;Polymyxin Ile-B1;Polymyxin B1 Isoleucine;N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-12-[(2S)-butan-2-yl]-3-[(1R)-1-hydroxyethyl]-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide;Polymyxin B1 Isoleucine Exclusive;Polymyxin I1
3 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • ManufacturerAK Scientific
  • Product number4956ED
  • Product descriptionN-[(2S)-4-Amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-12-[(2S)-butan-2-yl]-3-[(1R)-1-hydroxyethyl]-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide
  • Packaging1mg
  • Price$351
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14075
  • Product descriptionPolymyxin B1 Isoleucine ≥90%
  • Packaging500μg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14075
  • Product descriptionPolymyxin B1 Isoleucine ≥90%
  • Packaging1mg
  • Price$186
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4956ED N-[(2S)-4-Amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-12-[(2S)-butan-2-yl]-3-[(1R)-1-hydroxyethyl]-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide 1mg $351 2021-12-16 Buy
Cayman Chemical 14075 Polymyxin B1 Isoleucine ≥90% 500μg $98 2021-12-16 Buy
Cayman Chemical 14075 Polymyxin B1 Isoleucine ≥90% 1mg $186 2021-12-16 Buy

Properties


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Description

The polymyxins are cationic peptides originally isolated from B. polymyxa. They bind and kill Gram-negative bacteria. The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B1 Isoleucine differs from polymyxin B1 by having isoleucine rather than leucine as a component of the cyclic peptide. Polymyxin B1 isoleucine is comparable to other B polymyxins in its ability to kill P. aeruginosa, A. baumannii, and K. pneumoniae isolates. Its relative pharmacokinetics and nephrotoxicity have not been examined.