Pyrintegrin
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- $84 - $850
- Product name: Pyrintegrin
- CAS: 1228445-38-2
- MF: C23H25N5O3S
- MW: 451.54
- EINECS:
- MDL Number:MFCD25976569
- Synonyms:Pyrintegrin;N-(Cyclopropylmethyl)-4-{[4-(6-hydroxy-3,4-dihydro-1(2H)-quinolinyl)-2-pyrimidinyl]amino}benzenesulfonamide;N-(Cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]benzenesulfonamide;Benzenesulfonamide, N-(cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]-;nephropathy,C/EBPα,embryonic,stem,inhibit,β1-integrin,PPARγ,Integrin,Pyrintegrin,Adipogenic,cells,Inhibitor,podocyte-protective,ECM,proteinuria;Pyrintegrin, 10 mM in DMSO
14 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 2.5mg
- 5mg
- 10mg
- 50mg
- ManufacturerAK Scientific
- Product number3608DG
- Product descriptionPyrintegrin
- Packaging10mg
- Price$461
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3882
- Product descriptionPyrintegrin
- Packaging5mg
- Price$255
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16179
- Product descriptionPyrintegrin ≥95%
- Packaging1mg
- Price$84
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16179
- Product descriptionPyrintegrin ≥95%
- Packaging5mg
- Price$225
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16179
- Product descriptionPyrintegrin ≥95%
- Packaging10mg
- Price$328
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0003191
- Product descriptionPyrintegrin 97.04%
- Packaging5mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0003191
- Product descriptionPyrintegrin 97.04%
- Packaging10mg
- Price$265
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0003191
- Product descriptionPyrintegrin 97.04%
- Packaging50mg
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number48478
- Product descriptionPyrintegrin
- Packaging2.5mg
- Price$625
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number4978
- Product descriptionPyrintegrin ≥98%(HPLC)
- Packaging10
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberP994705
- Product descriptionPyrintegrin
- Packaging2.5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product numberP9523
- Product descriptionPyrintegrin
- Packaging1mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number366909
- Product descriptionPyrintegrin
- Packaging10mg
- Price$485
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number256373
- Product descriptionPyrintegrin
- Packaging10mg
- Price$644
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 3608DG | Pyrintegrin | 10mg | $461 | 2021-12-16 | Buy |
ApexBio Technology | C3882 | Pyrintegrin | 5mg | $255 | 2021-12-16 | Buy |
Cayman Chemical | 16179 | Pyrintegrin ≥95% | 1mg | $84 | 2024-03-01 | Buy |
Cayman Chemical | 16179 | Pyrintegrin ≥95% | 5mg | $225 | 2024-03-01 | Buy |
Cayman Chemical | 16179 | Pyrintegrin ≥95% | 10mg | $328 | 2024-03-01 | Buy |
ChemScene | CS-0003191 | Pyrintegrin 97.04% | 5mg | $180 | 2021-12-16 | Buy |
ChemScene | CS-0003191 | Pyrintegrin 97.04% | 10mg | $265 | 2021-12-16 | Buy |
ChemScene | CS-0003191 | Pyrintegrin 97.04% | 50mg | $850 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 48478 | Pyrintegrin | 2.5mg | $625 | 2021-12-16 | Buy |
Tocris | 4978 | Pyrintegrin ≥98%(HPLC) | 10 | $360 | 2021-12-16 | Buy |
TRC | P994705 | Pyrintegrin | 2.5mg | $130 | 2021-12-16 | Buy |
Usbiological | P9523 | Pyrintegrin | 1mg | $350 | 2021-12-16 | Buy |
Usbiological | 366909 | Pyrintegrin | 10mg | $485 | 2021-12-16 | Buy |
Usbiological | 256373 | Pyrintegrin | 10mg | $644 | 2021-12-16 | Buy |
Properties
Boiling point :729.3±70.0 °C(Predicted)
Density :1.401±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤1mg/ml in ethanol;30mg/ml in DMSO;50mg/ml in dimethyl formamide
form :crystalline solid
pka :9.75±0.20(Predicted)
color :Off-white to light yellow
Density :1.401±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤1mg/ml in ethanol;30mg/ml in DMSO;50mg/ml in dimethyl formamide
form :crystalline solid
pka :9.75±0.20(Predicted)
color :Off-white to light yellow
Safety Information
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Description
Human embryonic stem cells (hESC), unlike murine ESC, grow in vitro as large flattened two dimensional colonies. Dispersing these colonies, using trypsin to dissociate single hESC, results in massive cell death. Pyrintegrin is a 2,4-disubstituted pyrimidine that, at 2 μM, enhances the survival of hESC more than 30-fold after trypsin-mediated dissociation. It increases integrin-dependent attachment of hESC to extracellular matrices, including Matrigel? and laminin, without significantly impacting cell proliferation. Pyrintegrin increases the binding of the activated β1 integrin-specific antibody HUTS-21 and enhances the phosphorylation of multiple growth factor receptors and their downstream kinases, PI3K and MAPK.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
Career Henan Chemica Co
InvivoChem
Aladdin Scientific
Shanghai YuanYe Biotechnology Co., Ltd.
Shanghai Changyan Chem & Tech Co., Ltd.
Shanghai Chaolan Chemical Technology Center
Beijing Solarbio Science & Tecnology Co., Ltd.
Shanghai Dongyang Biotechnology Co., Ltd.