Pyrintegrin
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1物価
選択条件：
ブランド
- 富士フイルム和光純薬株式会社(wako)
パッケージ
- 10mg
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01TOC4978
- 製品説明
- 英語製品説明Pyrintegrin
- 包装単位10mg
- 価格￥127000
- 更新しました2024-03-01
- 購入
| 生産者 | 製品番号 | 製品説明 | 包装単位 | 価格 | 更新時間 | 購入 |
|---|---|---|---|---|---|---|
| 富士フイルム和光純薬株式会社(wako) | W01TOC4978 | Pyrintegrin |
10mg | ￥127000 | 2024-03-01 | 購入 |
プロパティ
沸点 :729.3±70.0 °C(Predicted)
比重(密度) :1.401±0.06 g/cm3(Predicted)
貯蔵温度 :Store at -20°C
溶解性 :≤1mg/ml in ethanol;30mg/ml in DMSO;50mg/ml in dimethyl formamide
外見 :crystalline solid
酸解離定数(Pka) :9.75±0.20(Predicted)
色 :Off-white to light yellow
比重(密度) :1.401±0.06 g/cm3(Predicted)
貯蔵温度 :Store at -20°C
溶解性 :≤1mg/ml in ethanol;30mg/ml in DMSO;50mg/ml in dimethyl formamide
外見 :crystalline solid
酸解離定数(Pka) :9.75±0.20(Predicted)
色 :Off-white to light yellow
安全情報
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説明
Human embryonic stem cells (hESC), unlike murine ESC, grow in vitro as large flattened two dimensional colonies. Dispersing these colonies, using trypsin to dissociate single hESC, results in massive cell death. Pyrintegrin is a 2,4-disubstituted pyrimidine that, at 2 μM, enhances the survival of hESC more than 30-fold after trypsin-mediated dissociation. It increases integrin-dependent attachment of hESC to extracellular matrices, including Matrigel? and laminin, without significantly impacting cell proliferation. Pyrintegrin increases the binding of the activated β1 integrin-specific antibody HUTS-21 and enhances the phosphorylation of multiple growth factor receptors and their downstream kinases, PI3K and MAPK.供給者とメーカー
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