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ChemicalBook >> CAS DataBase List >> Quizartinib

Quizartinib

$13 - $5280
Product name: Quizartinib
CAS: 950769-58-1
MF: C29H32N6O4S
MW: 560.67
EINECS:
MDL Number:MFCD18074524
Synonyms:N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea AC-220;quizartinib (FLT3 inhibitor);1-(5-(tert-Butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-y;Quizartinib AC-220;2-(4-AMinophenyl)-7-(2-Morpholin-4-yl-ethoxy)iMidazo[2,1-b]-[1,3]benzothiazole;N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-Morpholin-4-ylethoxy)iMidazo[2,1-b][1,3]benzothiazol-2-yl];AC220 (Quizartinib);AC220 (Quizartinib, AC010220)

Price88 Properties Safety Information Description

88 prices

Selected condition：

Brand

aablocks
AccelPharmtech
ACHEMBLOCK
Adipogen Life Sciences
AK Scientific
American Custom Chemicals Corporation
ApexBio Technology
Arctom
AvaChem
Biorbyt Ltd
Biosynth
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
Synthonix
Tocris
TRC
Usbiological

Package

20mg
10mM(1mLinDMSO)
1unit
500μg
EvaluationSample
10mM(in 1mL DMSO)
1mg
5mg
10mg
10mM*1mLinDMSO
10
50
25mg
0.05g
50mg
100mg
0.1g
0.25g
250mg
200mg
10mM(in1mLDMSO)
0.5g
500mg
1G
2g
5G
10G
50.00g
100.00g
250.00g

Manufactureraablocks
Product numberAA003A5P
Product descriptionN-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%
Packaging1mg
Price$13
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003A5P
Product descriptionN-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%
Packaging5mg
Price$20
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003A5P
Product descriptionN-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%
Packaging10mg
Price$24
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003A5P
Product descriptionN-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%
Packaging100mg
Price$64
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003A5P
Product descriptionN-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%
Packaging50mg
Price$42
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003A5P
Product descriptionN-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%
Packaging25mg
Price$34
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA003A5P
Product descriptionN-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%
Packaging250mg
Price$107
Updated2026-05-28
Buy

ManufacturerAccelPharmtech
Product numberYL1285
Product descriptionQuizartinib 99.00%
Packaging10G
Price$1710
Updated2026-05-21
Buy

ManufacturerAccelPharmtech
Product numberYL1285
Product descriptionQuizartinib 99.00%
Packaging5G
Price$1010
Updated2026-05-21
Buy

ManufacturerAccelPharmtech
Product numberYL1285
Product descriptionQuizartinib 99.00%
Packaging1G
Price$310
Updated2026-05-21
Buy

ManufacturerACHEMBLOCK
Product number10368
Product descriptionQuizartinib 98%
Packaging1G
Price$550
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product number10368
Product descriptionQuizartinib 98%
Packaging5MG
Price$30
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product number10368
Product descriptionQuizartinib 98%
Packaging25MG
Price$80
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product number10368
Product descriptionQuizartinib 98%
Packaging100MG
Price$180
Updated2026-05-27
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1003-M010
Product descriptionQuizartinib ≥95%
Packaging10mg
Price$335
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1003-M050
Product descriptionQuizartinib ≥95%
Packaging50mg
Price$961
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA003A5P	N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%	1mg	$13	2026-05-28	Buy
aablocks	AA003A5P	N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%	5mg	$20	2026-05-28	Buy
aablocks	AA003A5P	N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%	10mg	$24	2026-05-28	Buy
aablocks	AA003A5P	N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%	100mg	$64	2026-05-28	Buy
aablocks	AA003A5P	N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%	50mg	$42	2026-05-28	Buy
aablocks	AA003A5P	N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%	25mg	$34	2026-05-28	Buy
aablocks	AA003A5P	N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea 98%	250mg	$107	2026-05-28	Buy
AccelPharmtech	YL1285	Quizartinib 99.00%	10G	$1710	2026-05-21	Buy
AccelPharmtech	YL1285	Quizartinib 99.00%	5G	$1010	2026-05-21	Buy
AccelPharmtech	YL1285	Quizartinib 99.00%	1G	$310	2026-05-21	Buy
ACHEMBLOCK	10368	Quizartinib 98%	1G	$550	2026-05-27	Buy
ACHEMBLOCK	10368	Quizartinib 98%	5MG	$30	2026-05-27	Buy
ACHEMBLOCK	10368	Quizartinib 98%	25MG	$80	2026-05-27	Buy
ACHEMBLOCK	10368	Quizartinib 98%	100MG	$180	2026-05-27	Buy
Adipogen Life Sciences	SYN-1003-M010	Quizartinib ≥95%	10mg	$335	2026-05-06	Buy
Adipogen Life Sciences	SYN-1003-M050	Quizartinib ≥95%	50mg	$961	2026-05-06	Buy

Next Last

Properties

Density :1.39±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :White powder.
pka :12.59±0.70(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :CVWXJKQAOSCOAB-UHFFFAOYSA-N
SMILES :N(C1C=C(C(C)(C)C)ON=1)C(NC1=CC=C(C2=CN3C4=CC=C(OCCN5CCOCC5)C=C4SC3=N2)C=C1)=O

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

Description

Quizartinib is an inhibitor of FMS-related tyrosine kinase 3 (FLT3; Kd = 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases. It inhibits the proliferation of the human leukemia cell line MV4-11, which harbors a homozygous FLT3-ITD mutation, with an IC50 value of 0.56 nM. At 1 mg/kg/day, quizartinib has been shown to extend survival in a mouse model of FLT3-ITD acute myeloid leukemia and to eradicate tumors in an FLT3-dependent mouse xenograft model at 10 mg/kg.

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Suppliers and manufacturers

Shanghai Hope Chem Co., Ltd.， Shaanxi Istare Biotechnology Co., Ltd. Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited Beijing HwrkChemical Technology Co., Ltd Chemsky (shanghai) International Co.,Ltd Jinan Trio PharmaTech Co., Ltd. Shanghai Sunway Pharmaceutical Technology Co., Ltd Dalian Meilun Biotech Co., Ltd. T&W GROUP

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Quizartinib

Properties

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Description

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