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ChemicalBook >> CAS DataBase List >> (R)-(-)-IBUPROFEN

(R)-(-)-IBUPROFEN

(R)-(-)-IBUPROFEN price.
  • $33 - $1880
  • Product name: (R)-(-)-IBUPROFEN
  • CAS: 51146-57-7
  • MF: C13H18O2
  • MW: 206.29
  • EINECS:
  • MDL Number:MFCD00069290
  • Synonyms:(R)-(-)-2-(4-ISOBUTYLPHENYL)-PROPIONIC ACID;(R)-(-)-IBUPROFEN;(-)-Ibuprophen;Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-, (R)-;Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-, (αR)-;l-Ibuprofen;R-(-)-p-Isobutylhydratropic acid;(aR)-a-Methyl-4-(2-methylpropyl)benzeneacetic Acid
17 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • Medical Isotopes, Inc.
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 10MG
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product numberY1622
  • Product description(R)-(-)-Ibuprofen
  • Packaging100mg
  • Price$136
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA275175
  • Product description(R)-(-)-Ibuprofen 96%
  • Packaging100mg
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA275175
  • Product description(R)-(-)-Ibuprofen 96%
  • Packaging250mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA275175
  • Product description(R)-(-)-Ibuprofen 96%
  • Packaging1g
  • Price$261
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA275175
  • Product description(R)-(-)-Ibuprofen 96%
  • Packaging5g
  • Price$893
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0000086
  • Product description(R)-(-)-IBUPROFEN 95.00%
  • Packaging10MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1043
  • Product description(R)-(-)-Ibuprofen
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1043
  • Product description(R)-(-)-Ibuprofen
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3860
  • Product description(R)-(-)-Ibuprofen
  • Packaging25mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3860
  • Product description(R)-(-)-Ibuprofen
  • Packaging100mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16794
  • Product description(R)-Ibuprofen ≥98%
  • Packaging100mg
  • Price$77
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16794
  • Product description(R)-Ibuprofen ≥98%
  • Packaging250mg
  • Price$177
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16794
  • Product description(R)-Ibuprofen ≥98%
  • Packaging500mg
  • Price$333
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1394
  • Product description(R)-(-)-Ibuprofen 99.86%
  • Packaging200mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31001691
  • Product description(R)-(-)-Ibuprofen 96%
  • Packaging1g
  • Price$223
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number11087
  • Product description(R)-Ibuprofen
  • Packaging50mg
  • Price$1880
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y1622 (R)-(-)-Ibuprofen 100mg $136 2021-12-16 Buy
Ambeed A275175 (R)-(-)-Ibuprofen 96% 100mg $33 2021-12-16 Buy
Ambeed A275175 (R)-(-)-Ibuprofen 96% 250mg $72 2021-12-16 Buy
Ambeed A275175 (R)-(-)-Ibuprofen 96% 1g $261 2021-12-16 Buy
Ambeed A275175 (R)-(-)-Ibuprofen 96% 5g $893 2021-12-16 Buy
American Custom Chemicals Corporation API0000086 (R)-(-)-IBUPROFEN 95.00% 10MG $721.88 2021-12-16 Buy
ApexBio Technology B1043 (R)-(-)-Ibuprofen 100mg $50 2021-12-16 Buy
ApexBio Technology B1043 (R)-(-)-Ibuprofen 10mM(in 1mL DMSO) $50 2021-12-16 Buy
AvaChem 3860 (R)-(-)-Ibuprofen 25mg $69 2021-12-16 Buy
AvaChem 3860 (R)-(-)-Ibuprofen 100mg $129 2021-12-16 Buy
Cayman Chemical 16794 (R)-Ibuprofen ≥98% 100mg $77 2024-03-01 Buy
Cayman Chemical 16794 (R)-Ibuprofen ≥98% 250mg $177 2024-03-01 Buy
Cayman Chemical 16794 (R)-Ibuprofen ≥98% 500mg $333 2024-03-01 Buy
ChemScene CS-1394 (R)-(-)-Ibuprofen 99.86% 200mg $108 2021-12-16 Buy
Crysdot CD31001691 (R)-(-)-Ibuprofen 96% 1g $223 2021-12-16 Buy
Medical Isotopes, Inc. 11087 (R)-Ibuprofen 50mg $1880 2021-12-16 Buy

Properties

Melting point :41-42°C
Boiling point :305.14°C (rough estimate)
Density :1.0176 (rough estimate)
refractive index :1.5290 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form :White crystalline powder.
pka :4.41±0.10(Predicted)
color :Colourless to Pale Beige Oil
Water Solubility :369.3mg/L(25 ºC)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ibuprofen is a non-steroidal anti-inflammatory drug with diverse biochemical actions, most notably inhibiting COX-1 and COX-2 (IC50s = 2.6 and 1.53 μM, respectively). It is commonly synthesized as a racemic mixture of (S) and (R) isomers . (R)-Ibuprofen is an enantiomer that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids. The (R) enantiomer can, however, inhibit NF-κB activation (IC50 = 121.8 μM) in response to T-cell stimulation as well as block superoxide formation, β-glucuronidase release, and LTB4 generation by stimulated neutrophils (IC50 values range from 40-100 μM). 50-60% of (R)-ibuprofen is inverted to (S)-ibuprofen in humans after oral administration.

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