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ChemicalBook >> CAS DataBase List >> R-IMPP

R-IMPP

R-IMPP price.
  • $30 - $1950
  • Product name: R-IMPP
  • CAS: 2133832-83-2
  • MF: C24H27N3O2
  • MW: 389.49
  • EINECS:-0
  • MDL Number:MFCD31544323
  • Synonyms:R-IMPP;Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-;PF-00932239 (R-IMPP);(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide;Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases;R-IMPP, 10 mM in DMSO
40 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • Ambeed
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1G
  • Manufactureraablocks
  • Product numberAA01EAZV
  • Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99%
  • Packaging1mg
  • Price$30
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EAZV
  • Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99%
  • Packaging5mg
  • Price$64
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EAZV
  • Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99%
  • Packaging10mg
  • Price$115
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EAZV
  • Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99%
  • Packaging25mg
  • Price$243
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EAZV
  • Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99%
  • Packaging50mg
  • Price$434
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EAZV
  • Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99
  • Packaging100mg
  • Price$659
  • Updated2026-05-30
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65779
  • Product description(R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98%
  • Packaging1G
  • Price$1085
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65779
  • Product description(R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98%
  • Packaging100MG
  • Price$345
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65779
  • Product description(R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98%
  • Packaging25MG
  • Price$135
  • Updated2026-05-27
  • Buy
  • ManufacturerAmbeed
  • Product numberA395105
  • Product descriptionR-IMPP 98+%
  • Packaging100mg
  • Price$263
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395105
  • Product descriptionR-IMPP 98+%
  • Packaging250mg
  • Price$525
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395105
  • Product descriptionR-IMPP 98+%
  • Packaging1g
  • Price$1313
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395105
  • Product descriptionR-IMPP 98+%
  • Packaging50mg
  • Price$202
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395105
  • Product descriptionR-IMPP 98+%
  • Packaging10mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395105
  • Product descriptionR-IMPP 98+%
  • Packaging25mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395105
  • Product descriptionR-IMPP 98+%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01EAZV (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99% 1mg $30 2026-05-30 Buy
aablocks AA01EAZV (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99% 5mg $64 2026-05-30 Buy
aablocks AA01EAZV (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99% 10mg $115 2026-05-30 Buy
aablocks AA01EAZV (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99% 25mg $243 2026-05-30 Buy
aablocks AA01EAZV (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99% 50mg $434 2026-05-30 Buy
aablocks AA01EAZV (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99 100mg $659 2026-05-30 Buy
ACHEMBLOCK Q65779 (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98% 1G $1085 2026-05-27 Buy
ACHEMBLOCK Q65779 (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98% 100MG $345 2026-05-27 Buy
ACHEMBLOCK Q65779 (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98% 25MG $135 2026-05-27 Buy
Ambeed A395105 R-IMPP 98+% 100mg $263 2021-12-16 Buy
Ambeed A395105 R-IMPP 98+% 250mg $525 2021-12-16 Buy
Ambeed A395105 R-IMPP 98+% 1g $1313 2021-12-16 Buy
Ambeed A395105 R-IMPP 98+% 50mg $202 2021-12-16 Buy
Ambeed A395105 R-IMPP 98+% 10mg $119 2021-12-16 Buy
Ambeed A395105 R-IMPP 98+% 25mg $155 2021-12-16 Buy
Ambeed A395105 R-IMPP 98+% 5mg $84 2021-12-16 Buy

Properties

Boiling point :594.4±50.0 °C(Predicted)
Density :1.186±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 1 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :9.14±0.10(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC50 = 4.8 μM). It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels. (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of PCSK9 translation.