R-IMPP
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- $30 - $1950
- Product name: R-IMPP
- CAS: 2133832-83-2
- MF: C24H27N3O2
- MW: 389.49
- EINECS:-0
- MDL Number:MFCD31544323
- Synonyms:R-IMPP;Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-;PF-00932239 (R-IMPP);(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide;Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases;R-IMPP, 10 mM in DMSO
40 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- Ambeed
- Arctom
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA01EAZV
- Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99%
- Packaging1mg
- Price$30
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAZV
- Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99%
- Packaging5mg
- Price$64
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAZV
- Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99%
- Packaging10mg
- Price$115
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAZV
- Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99%
- Packaging25mg
- Price$243
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAZV
- Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99%
- Packaging50mg
- Price$434
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAZV
- Product description(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99
- Packaging100mg
- Price$659
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65779
- Product description(R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98%
- Packaging1G
- Price$1085
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65779
- Product description(R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98%
- Packaging100MG
- Price$345
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65779
- Product description(R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98%
- Packaging25MG
- Price$135
- Updated2026-05-27
- Buy
- ManufacturerAmbeed
- Product numberA395105
- Product descriptionR-IMPP 98+%
- Packaging100mg
- Price$263
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA395105
- Product descriptionR-IMPP 98+%
- Packaging250mg
- Price$525
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA395105
- Product descriptionR-IMPP 98+%
- Packaging1g
- Price$1313
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA395105
- Product descriptionR-IMPP 98+%
- Packaging50mg
- Price$202
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA395105
- Product descriptionR-IMPP 98+%
- Packaging10mg
- Price$119
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA395105
- Product descriptionR-IMPP 98+%
- Packaging25mg
- Price$155
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA395105
- Product descriptionR-IMPP 98+%
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01EAZV | (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99% | 1mg | $30 | 2026-05-30 | Buy |
| aablocks | AA01EAZV | (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99% | 5mg | $64 | 2026-05-30 | Buy |
| aablocks | AA01EAZV | (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99% | 10mg | $115 | 2026-05-30 | Buy |
| aablocks | AA01EAZV | (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99% | 25mg | $243 | 2026-05-30 | Buy |
| aablocks | AA01EAZV | (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99% | 50mg | $434 | 2026-05-30 | Buy |
| aablocks | AA01EAZV | (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 99 | 100mg | $659 | 2026-05-30 | Buy |
| ACHEMBLOCK | Q65779 | (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98% | 1G | $1085 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65779 | (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98% | 100MG | $345 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65779 | (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide 98% | 25MG | $135 | 2026-05-27 | Buy |
| Ambeed | A395105 | R-IMPP 98+% | 100mg | $263 | 2021-12-16 | Buy |
| Ambeed | A395105 | R-IMPP 98+% | 250mg | $525 | 2021-12-16 | Buy |
| Ambeed | A395105 | R-IMPP 98+% | 1g | $1313 | 2021-12-16 | Buy |
| Ambeed | A395105 | R-IMPP 98+% | 50mg | $202 | 2021-12-16 | Buy |
| Ambeed | A395105 | R-IMPP 98+% | 10mg | $119 | 2021-12-16 | Buy |
| Ambeed | A395105 | R-IMPP 98+% | 25mg | $155 | 2021-12-16 | Buy |
| Ambeed | A395105 | R-IMPP 98+% | 5mg | $84 | 2021-12-16 | Buy |
Properties
Boiling point :594.4±50.0 °C(Predicted)
Density :1.186±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 1 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :9.14±0.10(Predicted)
color :Light yellow to yellow
Density :1.186±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 1 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :9.14±0.10(Predicted)
color :Light yellow to yellow
Safety Information
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Description
(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC50 = 4.8 μM). It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels. (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of PCSK9 translation.Related product price
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