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ChemicalBook >> CAS DataBase List >> (R)-(+)-Nicoumalone

(R)-(+)-Nicoumalone

(R)-(+)-Nicoumalone price.
  • $135 - $1871.1
  • Product name: (R)-(+)-Nicoumalone
  • CAS: 66556-77-2
  • MF: C19H15NO6
  • MW: 353.33
  • EINECS:
  • MDL Number:MFCD00869568
  • Synonyms:(R)-(+)-Nicoumalone;(+)-3-(α-Acetonyl-4-nitrobenzyl)-4-hydroxycouMarin;Acenocoumarol Impurity 1(Acenocoumarol (R)-Isomer);2H-1-Benzopyran-2-one, 4-hydroxy-3-[(1R)-1-(4-nitrophenyl)-3-oxobutyl]-
14 prices
Selected condition:
Brand
  • aablocks
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • Manufactureraablocks
  • Product numberAA00FBFN
  • Product description(R)-(+)-Nicoumalone ≥98%
  • Packaging1mg
  • Price$188
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA00FBFN
  • Product description(R)-(+)-Nicoumalone ≥98%
  • Packaging5mg
  • Price$669
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA00FBFN
  • Product description(R)-(+)-Nicoumalone ≥98%
  • Packaging10mg
  • Price$1150
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2454DM
  • Product description(R)-Acenocoumarol
  • Packaging1mg
  • Price$248
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2454DM
  • Product description(R)-Acenocoumarol
  • Packaging5mg
  • Price$768
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2454DM
  • Product description(R)-Acenocoumarol
  • Packaging10mg
  • Price$1288
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008860
  • Product description(R)-ACENOCOUMAROL 95.00%
  • Packaging1MG
  • Price$240.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008860
  • Product description(R)-ACENOCOUMAROL 95.00%
  • Packaging10MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA16913
  • Product description(R)-Acenocoumarol
  • Packaging5mg
  • Price$1150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA16913
  • Product description(R)-Acenocoumarol
  • Packaging10mg
  • Price$1670
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number9000337
  • Product description(R)-Acenocoumarol ≥98%
  • Packaging1mg
  • Price$135
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9000337
  • Product description(R)-Acenocoumarol ≥98%
  • Packaging5mg
  • Price$601
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9000337
  • Product description(R)-Acenocoumarol ≥98%
  • Packaging10mg
  • Price$1068
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberA130790
  • Product description(R)-Acenocoumarol
  • Packaging1mg
  • Price$155
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00FBFN (R)-(+)-Nicoumalone ≥98% 1mg $188 2021-12-16 Buy
aablocks AA00FBFN (R)-(+)-Nicoumalone ≥98% 5mg $669 2021-12-16 Buy
aablocks AA00FBFN (R)-(+)-Nicoumalone ≥98% 10mg $1150 2021-12-16 Buy
AK Scientific 2454DM (R)-Acenocoumarol 1mg $248 2021-12-16 Buy
AK Scientific 2454DM (R)-Acenocoumarol 5mg $768 2021-12-16 Buy
AK Scientific 2454DM (R)-Acenocoumarol 10mg $1288 2021-12-16 Buy
American Custom Chemicals Corporation API0008860 (R)-ACENOCOUMAROL 95.00% 1MG $240.45 2021-12-16 Buy
American Custom Chemicals Corporation API0008860 (R)-ACENOCOUMAROL 95.00% 10MG $1871.1 2021-12-16 Buy
Biosynth Carbosynth FA16913 (R)-Acenocoumarol 5mg $1150 2021-12-16 Buy
Biosynth Carbosynth FA16913 (R)-Acenocoumarol 10mg $1670 2021-12-16 Buy
Cayman Chemical 9000337 (R)-Acenocoumarol ≥98% 1mg $135 2024-03-01 Buy
Cayman Chemical 9000337 (R)-Acenocoumarol ≥98% 5mg $601 2024-03-01 Buy
Cayman Chemical 9000337 (R)-Acenocoumarol ≥98% 10mg $1068 2024-03-01 Buy
TRC A130790 (R)-Acenocoumarol 1mg $155 2021-12-16 Buy

Properties

Boiling point :592.7±50.0 °C(Predicted)
Density :1.427±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 10 mg/ml; Ethanol: 0.2 mg/ml
form :A crystalline solid
pka :4.50±1.00(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Acenocoumarol is a short-lived oral anti-coagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase. It has higher intrinsic anticoagulant potency than warfarin and phenprocoumon, when evaluated in vitro. Acenocoumarol has a single chiral center that gives rise to two different enantiomeric forms. (R)-(+)-Acenocoumarol has a longer plasma elimination half-life (6.6 hours) and slower plasma clearance (1.9 L/h), compared to the (S)-()-enantiomer (1.8 hours, 28.5 L/h). The R-enantiomer is rapidly absorbed from the gastrointestinal tract with essentially complete oral bioavailability, whereas (S)-()-acenocoumarol undergoes extensive first-pass metabolism.