REVERSINE
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- $12 - $1802
- Product name: REVERSINE
- CAS: 656820-32-5
- MF: C21H27N7O
- MW: 393.49
- EINECS:
- MDL Number:MFCD07784513
- Synonyms:9H-Purine-2,6-diamine,N6-cyclohexyl-N2-[4-(4-morpholinyl)phenyl]-;N6-Cyclohexyl-N2-(4-morpholinophenyl)-7H-purine-2,6-diamine;2-(4-MORPHOLINOANILINO)-6-CYCLOHEXYLAMINOPURINE;N6-CYCLOHEXYL-N2-(4-MORPHOLINOPHENYL)-9H-PURINE-2,6-DIAMINE;Picropodophyllin (PPP);N6-Cyclohexyl-N2-[4-(4-morpholinyl)phenyl]-1H-purine-2,6-diamine Reversine;Reversine N6-Cyclohexyl-N2-[4-(4-morpholinyl)phenyl]-1H-purine-2,6-diamine;REVERSINE
84 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 2x5mg
- 250.00mg
- 10mM(in 1mL DMSO)
- 100.00mg
- 1.00g
- 10mM*1mLinDMSO
- 1000mg
- 1mg
- 5mg
- 10mg
- 50mg
- 1G
- 25MG
- 100mg
- 250mg
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA00FBFC
- Product descriptionReversine 98%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FBFC
- Product descriptionReversine 98%
- Packaging5mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FBFC
- Product descriptionReversine 98%
- Packaging10mg
- Price$17
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FBFC
- Product descriptionReversine 98%
- Packaging50mg
- Price$38
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FBFC
- Product descriptionReversine 98%
- Packaging100mg
- Price$63
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00FBFC
- Product descriptionReversine 98%
- Packaging250mg
- Price$106
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15324
- Product descriptionReversine 98%
- Packaging5MG
- Price$60
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15324
- Product descriptionReversine 98%
- Packaging100MG
- Price$395
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15324
- Product descriptionReversine 98%
- Packaging25MG
- Price$140
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM15324
- Product descriptionReversine 98%
- Packaging1G
- Price$1285
- Updated2026-05-27
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000788
- Product descriptionREVERSINE 95.00%
- Packaging5MG
- Price$726.73
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000788
- Product descriptionREVERSINE 95.00%
- Packaging25MG
- Price$1119.37
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000788
- Product descriptionREVERSINE 95.00%
- Packaging1MG
- Price$578.49
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3760
- Product descriptionReversine
- Packaging25mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3760
- Product descriptionReversine
- Packaging50mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3760
- Product descriptionReversine
- Packaging25mg
- Price$121
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00FBFC | Reversine 98% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA00FBFC | Reversine 98% | 5mg | $14 | 2026-05-28 | Buy |
| aablocks | AA00FBFC | Reversine 98% | 10mg | $17 | 2026-05-28 | Buy |
| aablocks | AA00FBFC | Reversine 98% | 50mg | $38 | 2026-05-28 | Buy |
| aablocks | AA00FBFC | Reversine 98% | 100mg | $63 | 2026-05-28 | Buy |
| aablocks | AA00FBFC | Reversine 98% | 250mg | $106 | 2026-05-28 | Buy |
| ACHEMBLOCK | M15324 | Reversine 98% | 5MG | $60 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15324 | Reversine 98% | 100MG | $395 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15324 | Reversine 98% | 25MG | $140 | 2026-05-27 | Buy |
| ACHEMBLOCK | M15324 | Reversine 98% | 1G | $1285 | 2026-05-27 | Buy |
| American Custom Chemicals Corporation | KIN0000788 | REVERSINE 95.00% | 5MG | $726.73 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000788 | REVERSINE 95.00% | 25MG | $1119.37 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000788 | REVERSINE 95.00% | 1MG | $578.49 | 2021-12-16 | Buy |
| ApexBio Technology | A3760 | Reversine | 25mg | $180 | 2021-12-16 | Buy |
| ApexBio Technology | A3760 | Reversine | 50mg | $250 | 2021-12-16 | Buy |
| ApexBio Technology | A3760 | Reversine | 25mg | $121 | 2026-05-06 | Buy |
Properties
Melting point :305℃ (decomposition)
Boiling point :736.4±70.0 °C(Predicted)
Density :1.343±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 7 mg/mL, soluble
form :solid
pka :10.51±0.10(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
InChI :1S/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,23,24,25,26,27)
InChIKey :ZFLJHSQHILSNCM-UHFFFAOYSA-N
SMILES :C1CCC(CC1)Nc2nc(Nc3ccc(cc3)N4CCOCC4)nc5nc[nH]c25
Boiling point :736.4±70.0 °C(Predicted)
Density :1.343±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 7 mg/mL, soluble
form :solid
pka :10.51±0.10(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
InChI :1S/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,23,24,25,26,27)
InChIKey :ZFLJHSQHILSNCM-UHFFFAOYSA-N
SMILES :C1CCC(CC1)Nc2nc(Nc3ccc(cc3)N4CCOCC4)nc5nc[nH]c25
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Reversine is a cell-permeable, 2,6-disubstituted purine analog that acts as a dedifferentiation-inducing agent. Reversine is shown to induce mouse C2C12 myoblast cells to become multipotent mesenchymal progenitor cells in the concentration range of 1-10 M. Reversine is also the first organic molecule that has been demonstrated to reverse the cellular differentiation process. The compound acts as a selective A3 adenosine receptor antagonist (Ki= 660 nM, >10 M, and >10 M for hA3, hA1, and hA2A, respectively. Reversine functions as a dual inhibitor of MEK1 and nonmuscle myosin II heavy chain (IC50 = 8 and 10 nM, respectively). The compound also acts as an ATP-competitive, reversible and selective inhibitor of ARK-1, ARK-2, and ARK-3 (IC50 = 400, 500 and 400 nM, respectively) in a 26-kinase panel.More related product prices
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