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ChemicalBook >> CAS DataBase List >> RI-1

RI-1

RI-1 price.
  • $5 - $2841
  • Product name: RI-1
  • CAS: 415713-60-9
  • MF: C14H11Cl3N2O3
  • MW: 361.61
  • EINECS:
  • MDL Number:MFCD00814248
  • Synonyms:3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione;RI-1, >=98%;RAD51 inhibitor RI-1;RAD51 inhibitor 1;3-Chloro-1-(3,4-dichlorophenyl)-4-Morpholino-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-;RI-1 >=98% (HPLC);RAD51 inhibitor
70 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
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  • Chemenu
  • ChemScene
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  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
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Package
  • 2x10mg
  • 25mg
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  • 10mM(1mLinDMSO)
  • 100.00mg
  • 250.00mg
  • 50
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  • 10
  • 1000mg
  • 1.00g
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 10mM*1mLinDMSO(Solution)
  • 250mg
  • 5G
  • 10mM(in 1mL DMSO)
  • 1g
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA00C6EU
  • Product descriptionRI-1 95%
  • Packaging100mg
  • Price$62
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C6EU
  • Product descriptionRI-1 95%
  • Packaging250mg
  • Price$117
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C6EU
  • Product descriptionRI-1 98%
  • Packaging5mg
  • Price$19
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6EU
  • Product descriptionRI-1 98%
  • Packaging1mg
  • Price$16
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00C6EU
  • Product descriptionRI-1 95%
  • Packaging1g
  • Price$303
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65688
  • Product description3-chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98%
  • Packaging1G
  • Price$295
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65688
  • Product description3-chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98%
  • Packaging5G
  • Price$1180
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65688
  • Product description3-chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98%
  • Packaging250MG
  • Price$140
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number2687AH
  • Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione
  • Packaging100mg
  • Price$142
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product number2687AH
  • Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione
  • Packaging250mg
  • Price$182
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA194418
  • Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
  • Packaging1g
  • Price$105
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA194418
  • Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
  • Packaging1mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA194418
  • Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
  • Packaging5mg
  • Price$8
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA194418
  • Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
  • Packaging10mg
  • Price$11
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA194418
  • Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
  • Packaging50mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA194418
  • Product description3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+%
  • Packaging100mg
  • Price$27
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C6EU RI-1 95% 100mg $62 2026-05-28 Buy
aablocks AA00C6EU RI-1 95% 250mg $117 2026-05-28 Buy
aablocks AA00C6EU RI-1 98% 5mg $19 2026-05-28 Buy
aablocks AA00C6EU RI-1 98% 1mg $16 2026-05-28 Buy
aablocks AA00C6EU RI-1 95% 1g $303 2026-05-28 Buy
ACHEMBLOCK Q65688 3-chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98% 1G $295 2026-05-27 Buy
ACHEMBLOCK Q65688 3-chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98% 5G $1180 2026-05-27 Buy
ACHEMBLOCK Q65688 3-chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98% 250MG $140 2026-05-27 Buy
AK Scientific 2687AH 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione 100mg $142 2021-12-16 Buy
AK Scientific 2687AH 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione 250mg $182 2021-12-16 Buy
Ambeed A194418 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% 1g $105 2021-12-16 Buy
Ambeed A194418 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% 1mg $5 2021-12-16 Buy
Ambeed A194418 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% 5mg $8 2021-12-16 Buy
Ambeed A194418 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% 10mg $11 2021-12-16 Buy
Ambeed A194418 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% 50mg $20 2021-12-16 Buy
Ambeed A194418 3-Chloro-1-(3,4-dichlorophenyl)-4-morpholino-1H-pyrrole-2,5-dione 98+% 100mg $27 2021-12-16 Buy

Properties

Boiling point :483.0±45.0 °C(Predicted)
Density :1.61
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :-3.45±0.20(Predicted)
form :powder
color :yellow to orange
biological source :human blood
Stability :Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChI :1S/C14H11Cl3N2O3/c15-9-2-1-8(7-10(9)16)19-13(20)11(17)12(14(19)21)18-3-5-22-6-4-18/h1-2,7H,3-6H2
InChIKey :MWSUIZKGNWELRF-UHFFFAOYSA-N
SMILES :ClC1=C(Cl)C=CC(N2C(C(N3CCOCC3)=C(Cl)C2=O)=O)=C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

RI-1 (415713-60-9) is a potent and selective inhibitor of RAD51 (IC50 = 5-30 μM), a highly conserved protein that catalyzes DNA repair via homologous recombination.1 It specifically reduces gene conversion in human cells and stimulates single strand annealing. It covalently binds to Cys319 on the surface of RAD51 and disrupts protein-protein interaction. It potentiates the effect of DNA-damaging agents on tumor cells and is a novel tool for studying DNA repair in cells.2 Potentiates the killing of glioblastoma cells by ionizing radiation3 and alkylating drugs4.

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