RO 48-8071
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- $12 - $1805
- Product name: RO 48-8071
- CAS: 189197-69-1
- MF: C23H27BrFNO2.C4H4O4
- MW: 564.45
- EINECS:
- MDL Number:MFCD05865242
- Synonyms:Ro 48-8071 fumarate salt;(4-((6-(allyl(methyl)amino)hexyl)oxy)-2-fluorophenyl)(4-bromophenyl)methanone fumarate Ro48-8071;(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone (2E)-2-butenedioate (1:1);OSC Inhibitor, Ro 48-8071 ;Aids163155;Aids-163155;Methanone, (4-bromophenyl)[2-fluoro-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl]-,(2E)-2-butenedioate;(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone
41 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Synthonix
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA002HYK
- Product descriptionRo 48-8071 Fumarate 95%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002HYK
- Product descriptionRo 48-8071 Fumarate 95%
- Packaging5mg
- Price$30
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002HYK
- Product descriptionRo 48-8071 Fumarate 95%
- Packaging10mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002HYK
- Product descriptionRo 48-8071 Fumarate 95%
- Packaging25mg
- Price$74
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002HYK
- Product descriptionRo 48-8071 Fumarate 98%
- Packaging50mg
- Price$100
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002HYK
- Product descriptionRo 48-8071 Fumarate 95%
- Packaging100mg
- Price$192
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002HYK
- Product descriptionRo 48-8071 Fumarate 95%
- Packaging250mg
- Price$328
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22570
- Product descriptionRO 48-8071 98%
- Packaging100MG
- Price$285
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22570
- Product descriptionRO 48-8071 98%
- Packaging1G
- Price$1710
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4012AH
- Product description(4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid
- Packaging100mg
- Price$628
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4012AH
- Product description(4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid
- Packaging5mg
- Price$113
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA674342
- Product descriptionRo48-8071fumarate 98+%
- Packaging50mg
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA674342
- Product descriptionRo48-8071fumarate 98+%
- Packaging25mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA674342
- Product descriptionRo48-8071fumarate 98+%
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA674342
- Product descriptionRo48-8071fumarate 98+%
- Packaging5mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0000522
- Product descriptionRO 48-8071 FUMARATE 95.00%
- Packaging5MG
- Price$761.66
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002HYK | Ro 48-8071 Fumarate 95% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA002HYK | Ro 48-8071 Fumarate 95% | 5mg | $30 | 2026-05-28 | Buy |
| aablocks | AA002HYK | Ro 48-8071 Fumarate 95% | 10mg | $44 | 2026-05-28 | Buy |
| aablocks | AA002HYK | Ro 48-8071 Fumarate 95% | 25mg | $74 | 2026-05-28 | Buy |
| aablocks | AA002HYK | Ro 48-8071 Fumarate 98% | 50mg | $100 | 2026-05-28 | Buy |
| aablocks | AA002HYK | Ro 48-8071 Fumarate 95% | 100mg | $192 | 2026-05-28 | Buy |
| aablocks | AA002HYK | Ro 48-8071 Fumarate 95% | 250mg | $328 | 2026-05-28 | Buy |
| ACHEMBLOCK | M22570 | RO 48-8071 98% | 100MG | $285 | 2026-05-27 | Buy |
| ACHEMBLOCK | M22570 | RO 48-8071 98% | 1G | $1710 | 2026-05-27 | Buy |
| AK Scientific | 4012AH | (4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid | 100mg | $628 | 2021-12-16 | Buy |
| AK Scientific | 4012AH | (4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid | 5mg | $113 | 2021-12-16 | Buy |
| Ambeed | A674342 | Ro48-8071fumarate 98+% | 50mg | $111 | 2021-12-16 | Buy |
| Ambeed | A674342 | Ro48-8071fumarate 98+% | 25mg | $85 | 2021-12-16 | Buy |
| Ambeed | A674342 | Ro48-8071fumarate 98+% | 10mg | $65 | 2021-12-16 | Buy |
| Ambeed | A674342 | Ro48-8071fumarate 98+% | 5mg | $44 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0000522 | RO 48-8071 FUMARATE 95.00% | 5MG | $761.66 | 2021-12-16 | Buy |
Properties
Melting point :90-92.7 °C
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: >5 mg/mL at ~60 °C
form :solid
color :white
Water Solubility :water: 5mg/mL
InChI :1S/C23H27BrFNO2/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18/h3,8-13,17H,1,4-7,14-16H2,2H3
InChIKey :CMYCCJYVZIMDFU-UHFFFAOYSA-N
SMILES :Fc1c(ccc(c1)OCCCCCCN(CC=C)C)C(=O)c2ccc(cc2)Br
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: >5 mg/mL at ~60 °C
form :solid
color :white
Water Solubility :water: 5mg/mL
InChI :1S/C23H27BrFNO2/c1-3-14-26(2)15-6-4-5-7-16-28-20-12-13-21(22(25)17-20)23(27)18-8-10-19(24)11-9-18/h3,8-13,17H,1,4-7,14-16H2,2H3
InChIKey :CMYCCJYVZIMDFU-UHFFFAOYSA-N
SMILES :Fc1c(ccc(c1)OCCCCCCN(CC=C)C)C(=O)c2ccc(cc2)Br
Safety Information
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Description
Ro 48-8071 fumarate is an orally active 2,3-oxidosqualene lanosterol cyclase (OSC) inhibitor where OSC represents a unique target for a cholesterol-lowering drug. Partial inhibition of OSC should reduce synthesis of lanosterol and subsequent sterols, and also stimulate the production of epoxysterols that repress HMG-CoA reductase expression, generating a synergistic, self-limited negative regulatory loop.More related product prices
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Suppliers and manufacturers
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