Regorafenib
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- $25 - $1208.7
- Product name: Regorafenib
- CAS: 755037-03-7
- MF: C21H15ClF4N4O3
- MW: 482.82
- EINECS:815-051-1
- MDL Number:MFCD16038047
- Synonyms:4-[4-({[4-chioro-3-(trifluoroMethyl)phenyl]carbaMoyl}aMino)-3-fluorophenoxy]-pyridine-2-carboxylic acid MethylaMide;REGORAFENIB BAY 73-4506 BAYER HEALTHCARE (SEE ALSO COLORECTAL, LUNG, STOMACH) PHASE II(REGORAFENIB) PHARMACEUTICALS (888) 842-2937WAYNE, NJ;4-[4-[[[[4-Chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]-3-fluorophenoxy]-N-Methyl-2-pyridinecarboxaMide;4-[4-[N'-(4-Chloro-3-trifluoroMethylphenyl)ureido]-3- fluorophenoxy]pyridine-2-carboxylic Acid MethylaMide;regorafinib;Regafenib;Reggae sorafenib;Regorafenib C3X-1410
54 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- DC Chemicals
- TCI Chemical
- TRC
- Usbiological
Package
- 10mM(in1mLDMSO)
- 20mg
- 2x50mg
- 250mg
- 1g
- 5g
- 10mM(in 1mL DMSO)
- 10g
- EvaluationSample
- 1mg
- 1unit
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3623-M005
- Product descriptionRegorafenib ≥98%(HPLC)
- Packaging5mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1169-M001
- Product descriptionRegorafenib ≥95%
- Packaging1mg
- Price$86
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3623-M025
- Product descriptionRegorafenib ≥98%(HPLC)
- Packaging25mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1169-M005
- Product descriptionRegorafenib ≥95%
- Packaging5mg
- Price$140
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1169-M010
- Product descriptionRegorafenib ≥95%
- Packaging10mg
- Price$216
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3623-M005
- Product descriptionRegorafenib ≥98%(HPLC)
- Packaging5mg
- Price$35
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1169-M050
- Product descriptionRegorafenib ≥95%
- Packaging50mg
- Price$702
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberSYN1169
- Product descriptionRegorafenib
- Packaging100mg
- Price$1065
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1169
- Product descriptionRegorafenib
- Packaging10mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1169
- Product descriptionRegorafenib
- Packaging1mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000417
- Product descriptionBAY-73-4506 95.00%
- Packaging1MG
- Price$426
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8236
- Product descriptionRegorafenib
- Packaging200mg
- Price$324
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8236
- Product descriptionRegorafenib
- Packaging50mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8236
- Product descriptionRegorafenib
- Packaging10mg
- Price$51
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8236
- Product descriptionRegorafenib
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8236
- Product descriptionRegorafenib
- PackagingEvaluationSample
- Price$30
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3623-M005 | Regorafenib ≥98%(HPLC) | 5mg | $25 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1169-M001 | Regorafenib ≥95% | 1mg | $86 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3623-M025 | Regorafenib ≥98%(HPLC) | 25mg | $90 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1169-M005 | Regorafenib ≥95% | 5mg | $140 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1169-M010 | Regorafenib ≥95% | 10mg | $216 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3623-M005 | Regorafenib ≥98%(HPLC) | 5mg | $35 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1169-M050 | Regorafenib ≥95% | 50mg | $702 | 2026-05-06 | Buy |
| AK Scientific | SYN1169 | Regorafenib | 100mg | $1065 | 2021-12-16 | Buy |
| AK Scientific | SYN1169 | Regorafenib | 10mg | $220 | 2021-12-16 | Buy |
| AK Scientific | SYN1169 | Regorafenib | 1mg | $100 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000417 | BAY-73-4506 95.00% | 1MG | $426 | 2021-12-16 | Buy |
| ApexBio Technology | A8236 | Regorafenib | 200mg | $324 | 2026-05-06 | Buy |
| ApexBio Technology | A8236 | Regorafenib | 50mg | $100 | 2021-12-16 | Buy |
| ApexBio Technology | A8236 | Regorafenib | 10mg | $51 | 2026-05-06 | Buy |
| ApexBio Technology | A8236 | Regorafenib | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8236 | Regorafenib | EvaluationSample | $30 | 2026-05-06 | Buy |
Properties
Melting point :206.0 to 210.0 °C
Boiling point :513.4±50.0 °C(Predicted)
Density :1.491±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.04±0.70(Predicted)
form :White powder.
color :Pale Pink to Light Pink
InChI :InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)
InChIKey :FNHKPVJBJVTLMP-UHFFFAOYSA-N
SMILES :C1(C(NC)=O)=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=C1
CAS DataBase Reference :755037-03-7
Boiling point :513.4±50.0 °C(Predicted)
Density :1.491±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.04±0.70(Predicted)
form :White powder.
color :Pale Pink to Light Pink
InChI :InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)
InChIKey :FNHKPVJBJVTLMP-UHFFFAOYSA-N
SMILES :C1(C(NC)=O)=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=C1
CAS DataBase Reference :755037-03-7
Safety Information
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Description
Regorafenib is an orally-bioavailable multi-kinase inhibitor that is structurally related to sorafenib (BAY 43-9006; ), another multi-kinase inhibitor with applications in cancer. Regorafenib inhibits c-Raf, B-Raf, VEGFR1, VEGFR2, VEGFR3, Tie2, PDGFRβ, FGFR1, c-Kit, and RET with IC50 values of 2.5, 28, 13, 4.2, 46, 311, 22, 202, 7, and 1.5 nM, respectively, as well as other kinases. It also inhibits soluble epoxide hydrolase (IC50 = 0.5 nM). Regorafenib has value against a range of cancers, including advanced colorectal cancer.More related product prices
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Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
