Regorafenib
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- $9 - $1208.7
- Product name: Regorafenib
- CAS: 755037-03-7
- MF: C21H15ClF4N4O3
- MW: 482.82
- EINECS:815-051-1
- MDL Number:MFCD16038047
- Synonyms:4-[4-({[4-chioro-3-(trifluoroMethyl)phenyl]carbaMoyl}aMino)-3-fluorophenoxy]-pyridine-2-carboxylic acid MethylaMide;REGORAFENIB BAY 73-4506 BAYER HEALTHCARE (SEE ALSO COLORECTAL, LUNG, STOMACH) PHASE II(REGORAFENIB) PHARMACEUTICALS (888) 842-2937WAYNE, NJ;4-[4-[[[[4-Chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]-3-fluorophenoxy]-N-Methyl-2-pyridinecarboxaMide;4-[4-[N'-(4-Chloro-3-trifluoroMethylphenyl)ureido]-3- fluorophenoxy]pyridine-2-carboxylic Acid MethylaMide;regorafinib;Regafenib;Reggae sorafenib;Regorafenib C3X-1410
80 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- DC Chemicals
- Matrix Scientific
- TCI Chemical
- TRC
- Usbiological
Package
- 10mM(in1mLDMSO)
- 1unit
- 5mg
- 10mg
- 25mg
- 1mg
- 10mM*1mLinDMSO
- 20mg
- EvaluationSample
- 10mM(in 1mL DMSO)
- 50mg
- 2x50mg
- 100MG
- 200mg
- 250mg
- 1.00g
- 1g
- 5.00g
- 5g
- 10g
- 25g
- 25.00g
- Manufactureraablocks
- Product numberAA00ICKB
- Product description4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98%
- Packaging1mg
- Price$9
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00ICKB
- Product description4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98%
- Packaging250mg
- Price$36
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00ICKB
- Product description4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98%
- Packaging1g
- Price$64
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00ICKB
- Product description4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98%
- Packaging5g
- Price$274
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00ICKB
- Product description4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98%
- Packaging10g
- Price$474
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00ICKB
- Product description4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98%
- Packaging25g
- Price$940
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16040
- Product descriptionRegorafenib 99%
- Packaging5G
- Price$280
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16040
- Product descriptionRegorafenib 99%
- Packaging100MG
- Price$40
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16040
- Product descriptionRegorafenib 99%
- Packaging1G
- Price$90
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3623-M025
- Product descriptionRegorafenib ≥98%(HPLC)
- Packaging25mg
- Price$90
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1169-M001
- Product descriptionRegorafenib ≥95%
- Packaging1mg
- Price$86
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3623-M005
- Product descriptionRegorafenib ≥98%(HPLC)
- Packaging5mg
- Price$35
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3623-M005
- Product descriptionRegorafenib ≥98%(HPLC)
- Packaging5mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1169-M010
- Product descriptionRegorafenib ≥95%
- Packaging10mg
- Price$216
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1169-M005
- Product descriptionRegorafenib ≥95%
- Packaging5mg
- Price$140
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1169-M050
- Product descriptionRegorafenib ≥95%
- Packaging50mg
- Price$702
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ICKB | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98% | 1mg | $9 | 2026-05-29 | Buy |
| aablocks | AA00ICKB | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98% | 250mg | $36 | 2026-05-29 | Buy |
| aablocks | AA00ICKB | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98% | 1g | $64 | 2026-05-29 | Buy |
| aablocks | AA00ICKB | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98% | 5g | $274 | 2026-05-29 | Buy |
| aablocks | AA00ICKB | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98% | 10g | $474 | 2026-05-29 | Buy |
| aablocks | AA00ICKB | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 98% | 25g | $940 | 2026-05-29 | Buy |
| ACHEMBLOCK | R16040 | Regorafenib 99% | 5G | $280 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16040 | Regorafenib 99% | 100MG | $40 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16040 | Regorafenib 99% | 1G | $90 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-3623-M025 | Regorafenib ≥98%(HPLC) | 25mg | $90 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1169-M001 | Regorafenib ≥95% | 1mg | $86 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3623-M005 | Regorafenib ≥98%(HPLC) | 5mg | $35 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3623-M005 | Regorafenib ≥98%(HPLC) | 5mg | $25 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1169-M010 | Regorafenib ≥95% | 10mg | $216 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1169-M005 | Regorafenib ≥95% | 5mg | $140 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1169-M050 | Regorafenib ≥95% | 50mg | $702 | 2026-05-06 | Buy |
Properties
Melting point :206.0 to 210.0 °C
Boiling point :513.4±50.0 °C(Predicted)
Density :1.491±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.04±0.70(Predicted)
form :White powder.
color :Pale Pink to Light Pink
InChI :InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)
InChIKey :FNHKPVJBJVTLMP-UHFFFAOYSA-N
SMILES :C1(C(NC)=O)=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=C1
CAS DataBase Reference :755037-03-7
Boiling point :513.4±50.0 °C(Predicted)
Density :1.491±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.04±0.70(Predicted)
form :White powder.
color :Pale Pink to Light Pink
InChI :InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)
InChIKey :FNHKPVJBJVTLMP-UHFFFAOYSA-N
SMILES :C1(C(NC)=O)=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=C1
CAS DataBase Reference :755037-03-7
Safety Information
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Description
Regorafenib is an orally-bioavailable multi-kinase inhibitor that is structurally related to sorafenib (BAY 43-9006; ), another multi-kinase inhibitor with applications in cancer. Regorafenib inhibits c-Raf, B-Raf, VEGFR1, VEGFR2, VEGFR3, Tie2, PDGFRβ, FGFR1, c-Kit, and RET with IC50 values of 2.5, 28, 13, 4.2, 46, 311, 22, 202, 7, and 1.5 nM, respectively, as well as other kinases. It also inhibits soluble epoxide hydrolase (IC50 = 0.5 nM). Regorafenib has value against a range of cancers, including advanced colorectal cancer.More related product prices
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Suppliers and manufacturers
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BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
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Henan Tianfu Chemical Co.,Ltd.
Regorafenib
CAS:755037-03-7