Rimegepant
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- $43 - $15225
- Product name: Rimegepant
- CAS: 1289023-67-1
- MF: C28H28F2N6O3
- MW: 534.56
- EINECS:
- MDL Number:MFCD23098777
- Synonyms:4-(2,3-Dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-1-piperidinecarboxylic acid (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester;Rimegepant;CS-2806;BMS-927711(Rimegepant);BMS 92771;RIMEGEPANT;BMS-927711;BMS927711;BMS 92771;(5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-, (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl ester
22 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 2mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0045899
- Product description4-(2,3-DIHYDRO-2-OXO-1H-IMIDAZO[4,5-B]PYRIDIN-1-YL)-1-PIPERIDINECARBOXYLIC ACID (5S,6S,9R)-5-AMINO-6-(2,3-DIFLUOROPHENYL)-6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]PYRIDIN-9-YL ESTER 95.00%
- Packaging5MG
- Price$495.23
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3259
- Product descriptionBMS-927711
- Packaging2mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3259
- Product descriptionBMS-927711
- Packaging5mg
- Price$299
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3259
- Product descriptionBMS-927711
- Packaging10mg
- Price$457
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3259
- Product descriptionBMS-927711
- Packaging50mg
- Price$1496
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573258
- Product descriptionBMS-927711(Rimegepant) >98%
- Packaging100mg
- Price$1283.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573258
- Product descriptionBMS-927711(Rimegepant) >98%
- Packaging250mg
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573258
- Product descriptionBMS-927711(Rimegepant) >98%
- Packaging1g
- Price$4321.4
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number26338
- Product descriptionRimegepant
- Packaging1mg
- Price$43
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number26338
- Product descriptionRimegepant
- Packaging5mg
- Price$189
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number26338
- Product descriptionRimegepant
- Packaging10mg
- Price$334
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number26338
- Product descriptionRimegepant
- Packaging25mg
- Price$678
- Updated2023-06-20
- Buy
- ManufacturerChemScene
- Product numberCS-1027
- Product descriptionRimegepant 99.08%
- Packaging5mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1027
- Product descriptionRimegepant 99.08%
- Packaging10mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1027
- Product descriptionRimegepant 99.08%
- Packaging50mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003993
- Product descriptionBMS-927711 98+%
- Packaging5mg
- Price$176
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0045899 | 4-(2,3-DIHYDRO-2-OXO-1H-IMIDAZO[4,5-B]PYRIDIN-1-YL)-1-PIPERIDINECARBOXYLIC ACID (5S,6S,9R)-5-AMINO-6-(2,3-DIFLUOROPHENYL)-6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]PYRIDIN-9-YL ESTER 95.00% | 5MG | $495.23 | 2021-12-16 | Buy |
| ApexBio Technology | A3259 | BMS-927711 | 2mg | $173 | 2021-12-16 | Buy |
| ApexBio Technology | A3259 | BMS-927711 | 5mg | $299 | 2021-12-16 | Buy |
| ApexBio Technology | A3259 | BMS-927711 | 10mg | $457 | 2021-12-16 | Buy |
| ApexBio Technology | A3259 | BMS-927711 | 50mg | $1496 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573258 | BMS-927711(Rimegepant) >98% | 100mg | $1283.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573258 | BMS-927711(Rimegepant) >98% | 250mg | $2245.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573258 | BMS-927711(Rimegepant) >98% | 1g | $4321.4 | 2021-12-16 | Buy |
| Cayman Chemical | 26338 | Rimegepant | 1mg | $43 | 2023-06-20 | Buy |
| Cayman Chemical | 26338 | Rimegepant | 5mg | $189 | 2023-06-20 | Buy |
| Cayman Chemical | 26338 | Rimegepant | 10mg | $334 | 2023-06-20 | Buy |
| Cayman Chemical | 26338 | Rimegepant | 25mg | $678 | 2023-06-20 | Buy |
| ChemScene | CS-1027 | Rimegepant 99.08% | 5mg | $140 | 2021-12-16 | Buy |
| ChemScene | CS-1027 | Rimegepant 99.08% | 10mg | $240 | 2021-12-16 | Buy |
| ChemScene | CS-1027 | Rimegepant 99.08% | 50mg | $750 | 2021-12-16 | Buy |
| Crysdot | CD31003993 | BMS-927711 98+% | 5mg | $176 | 2021-12-16 | Buy |
Properties
Density :1.45±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :A crystalline solid
pka :12.03±0.20(Predicted)
color :White to off-white
InChIKey :KRNAOFGYEFKHPB-ANJVHQHFSA-N
SMILES :N1(C(O[C@H]2C3=NC=CC=C3[C@@H](N)[C@H](C3=CC=CC(F)=C3F)CC2)=O)CCC(N2C3=CC=CN=C3NC2=O)CC1
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :A crystalline solid
pka :12.03±0.20(Predicted)
color :White to off-white
InChIKey :KRNAOFGYEFKHPB-ANJVHQHFSA-N
SMILES :N1(C(O[C@H]2C3=NC=CC=C3[C@@H](N)[C@H](C3=CC=CC(F)=C3F)CC2)=O)CCC(N2C3=CC=CN=C3NC2=O)CC1
Safety Information
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Description
Rimegepant (Nurtec ODT)(FDA approved in February 2020) is an ODT available in a single strength of 75 mg for the acute treatment of migraine with or without aura in adults.No more than 75 mg should be taken in a 24-hour period. while there are no contraindications，concomitant administration with CYP3A4 inhibitors should be avoided.The most common adverse reaction is nausea, occurring in few patients (rimegepant PI, 2020). In clinical trials, a single 75-mg dose of rimegepant demonstrated superiority over placebo with regard to freedom from pain (21% in the rimegepant group vs.11% in the placebo group) and freedom from the most bothersome symptom (35% vs. 27%) at 2 hours post dose (Croop et al., 2019). Rimegepant is not approved for migraine prevention, although it is presently in late-stage clinical trials assessing it for that indication(NCT03732638,2020).Suppliers and manufacturers
Changsha Junyu Chemexpress.co., Ltd
Senova Technology Co. Ltd.
Heading （Nanjing）Pharmtechnologies Co., Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Jinan Carbotang Biotech Co.,Ltd.
