Ripasudil
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- $154 - $1925
- Product name: Ripasudil
- CAS: 223645-67-8
- MF: C15H18FN3O2S
- MW: 323.39
- EINECS:-0
- MDL Number:MFCD28291829
- Synonyms:k115 free base;Ripasudil;4-Fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]isoquinoline;RIPASUDIL FREE BASE;K 115 FREE BASE;K115 FREE BASE;CS-1564;K-115, Ripasudil;Isoquinoline, 4-fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-;RIPASUDIL HYDROCHLOIDE
10 prices
Selected condition：
Brand
- aablocks
- Chemenu
- Crysdot
- CSNpharm
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA00BF3B
- Product descriptionK-115 >98%(HPLC)
- Packaging5mg
- Price$283
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF3B
- Product descriptionK-115 >98%(HPLC)
- Packaging10mg
- Price$398
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF3B
- Product descriptionK-115 >98%(HPLC)
- Packaging25mg
- Price$762
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF3B
- Product descriptionK-115 >98%(HPLC)
- Packaging50mg
- Price$1192
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BF3B
- Product descriptionK-115 >98%(HPLC)
- Packaging100mg
- Price$1925
- Updated2026-05-28
- Buy
- ManufacturerChemenu
- Product numberCM146182
- Product description(S)-4-fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline 98%
- Packaging100mg
- Price$880
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002611
- Product descriptionK-115 free base 98+%
- Packaging1g
- Price$1290
- Updated2026-05-27
- Buy
- ManufacturerCrysdot
- Product numberCD31002611
- Product descriptionK-115 free base 98+%
- Packaging250mg
- Price$515
- Updated2026-05-27
- Buy
- ManufacturerCSNpharm
- Product numberCSN16953
- Product descriptionK-115
- Packaging25mg
- Price$557
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN16953
- Product descriptionK-115
- Packaging5mg
- Price$154
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BF3B | K-115 >98%(HPLC) | 5mg | $283 | 2026-05-28 | Buy |
| aablocks | AA00BF3B | K-115 >98%(HPLC) | 10mg | $398 | 2026-05-28 | Buy |
| aablocks | AA00BF3B | K-115 >98%(HPLC) | 25mg | $762 | 2026-05-28 | Buy |
| aablocks | AA00BF3B | K-115 >98%(HPLC) | 50mg | $1192 | 2026-05-28 | Buy |
| aablocks | AA00BF3B | K-115 >98%(HPLC) | 100mg | $1925 | 2026-05-28 | Buy |
| Chemenu | CM146182 | (S)-4-fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline 98% | 100mg | $880 | 2021-12-16 | Buy |
| Crysdot | CD31002611 | K-115 free base 98+% | 1g | $1290 | 2026-05-27 | Buy |
| Crysdot | CD31002611 | K-115 free base 98+% | 250mg | $515 | 2026-05-27 | Buy |
| CSNpharm | CSN16953 | K-115 | 25mg | $557 | 2021-12-16 | Buy |
| CSNpharm | CSN16953 | K-115 | 5mg | $154 | 2021-12-16 | Buy |
Properties
Boiling point :497.2±55.0 °C(Predicted)
Density :1.293±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO
form :powder
pka :9.70±0.40(Predicted)
color :white to beige
Water Solubility :H2O: 2mg/mL, clear
InChI :1S/C15H18FN3O2S/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14/h2,4-5,9-11,17H,3,6-8H2,1H3/t11-/m0/s1
InChIKey :QSKQVZWVLOIIEV-NSHDSACASA-N
SMILES :Fc1c2c(cnc1)cccc2[S](=O)(=O)N3[C@H](CNCCC3)C
Density :1.293±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO
form :powder
pka :9.70±0.40(Predicted)
color :white to beige
Water Solubility :H2O: 2mg/mL, clear
InChI :1S/C15H18FN3O2S/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14/h2,4-5,9-11,17H,3,6-8H2,1H3/t11-/m0/s1
InChIKey :QSKQVZWVLOIIEV-NSHDSACASA-N
SMILES :Fc1c2c(cnc1)cccc2[S](=O)(=O)N3[C@H](CNCCC3)C
Safety Information
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Description
Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
Chemvon Biotechnology Co., Ltd
BOC Sciences
SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD
MedChemexpress LLC
Nanjing Sunlida Biological Technology Co., Ltd.
Sichuan Wei Keqi Biological Technology Co., Ltd.
Suzhou Haiheng Biological Pharmaceutical Co., Ltd.
Pharmacodia (Beijing) Co.,Ltd
ShangHai Biochempartner Co.,Ltd