ChemicalBook >> CAS DataBase List >>Ripasudil
Ripasudil
- CAS No.
- 223645-67-8
- Chemical Name:
- Ripasudil
- Synonyms
- CS-1564;Ripasudil;k115 free base;K-115, Ripasudil;RIPASUDIL HYDROCHLOIDE;RIPASUDIL FREE BASE;K 115 FREE BASE;K115 FREE BASE;4-Fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]isoquinoline;Isoquinoline, 4-fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-
- CBNumber:
- CB92722374
- Molecular Formula:
- C15H18FN3O2S
- Molecular Weight:
- 323.39
- MDL Number:
- MFCD28291829
- MOL File:
- 223645-67-8.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:18
| Boiling point | 497.2±55.0 °C(Predicted) |
|---|---|
| Density | 1.293±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Soluble in DMSO |
| pka | 9.70±0.40(Predicted) |
| FDA UNII | 11978226XX |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Ripasudil price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| CSNpharm | CSN16953 | K-115 | 223645-67-8 | 5mg | $154 | 2021-12-16 | Buy |
| Crysdot | CD31002611 | K-115freebase 98+% | 223645-67-8 | 250mg | $515 | 2021-12-16 | Buy |
| CSNpharm | CSN16953 | K-115 | 223645-67-8 | 25mg | $557 | 2021-12-16 | Buy |
| Chemenu | CM146182 | (S)-4-fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline 98% | 223645-67-8 | 100mg | $880 | 2021-12-16 | Buy |
| Crysdot | CD31002611 | K-115freebase 98+% | 223645-67-8 | 1g | $1290 | 2021-12-16 | Buy |
Ripasudil Chemical Properties,Uses,Production
Description
Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.
Definition
ChEBI: Ripasudil is a member of isoquinolines.
Ripasudil Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 54)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4022 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 |
223645-67-8(Ripasudil)Related Search:
k115 free base
Ripasudil
4-Fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]isoquinoline
RIPASUDIL FREE BASE;K 115 FREE BASE;K115 FREE BASE
CS-1564
K-115, Ripasudil
Isoquinoline, 4-fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-
RIPASUDIL HYDROCHLOIDE
223645-67-8