Ritlecitinib
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- $80 - $2315
- Product name: Ritlecitinib
- CAS: 1792180-81-4
- MF: C15H19N5O
- MW: 285.34
- EINECS:210-077-2
- MDL Number:MFCD31697544
- Synonyms:1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one;EOS-61890;1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2;CS-2733;PF-06651600;PF 06651600;PF06651600;1-[(2S,5R)-2-methyl-5(7H-pyrrolo[2,3-d]pyrimidine-4-ylamino)-1-piperidinly]-2-propen-1-one malonate,PF06651600;2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-;1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one
11 prices
Selected condition：
Brand
- Alichem
- American Custom Chemicals Corporation
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAlichem
- Product number1792180814
- Product description1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one
- Packaging100mg
- Price$829.25
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002534
- Product descriptionPF-06651600 95.00%
- Packaging5MG
- Price$457.78
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0020243
- Product descriptionRitlecitinib 99.98%
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0020243
- Product descriptionRitlecitinib 99.98%
- Packaging10mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0020243
- Product descriptionRitlecitinib 99.98%
- Packaging25mg
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0020243
- Product descriptionRitlecitinib 99.98%
- Packaging50mg
- Price$520
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10779
- Product descriptionPF-06651600 >98%，ee>98%
- Packaging250mg
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberPZ0316
- Product descriptionPF-06651600 ≥98% (HPLC)
- Packaging25MG
- Price$340.1
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberPZ0316
- Product descriptionPF-06651600 ≥98% (HPLC)
- Packaging5MG
- Price$111.15
- Updated2025-07-31
- Buy
- ManufacturerUsbiological
- Product number462323
- Product descriptionPF-06651600
- Packaging1mg
- Price$319
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number474159
- Product descriptionPF06651600
- Packaging100mg
- Price$2315
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Alichem | 1792180814 | 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one | 100mg | $829.25 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002534 | PF-06651600 95.00% | 5MG | $457.78 | 2021-12-16 | Buy |
| ChemScene | CS-0020243 | Ritlecitinib 99.98% | 5mg | $80 | 2021-12-16 | Buy |
| ChemScene | CS-0020243 | Ritlecitinib 99.98% | 10mg | $140 | 2021-12-16 | Buy |
| ChemScene | CS-0020243 | Ritlecitinib 99.98% | 25mg | $310 | 2021-12-16 | Buy |
| ChemScene | CS-0020243 | Ritlecitinib 99.98% | 50mg | $520 | 2021-12-16 | Buy |
| DC Chemicals | DC10779 | PF-06651600 >98%，ee>98% | 250mg | $1200 | 2021-12-16 | Buy |
| Sigma-Aldrich | PZ0316 | PF-06651600 ≥98% (HPLC) | 25MG | $340.1 | 2025-07-31 | Buy |
| Sigma-Aldrich | PZ0316 | PF-06651600 ≥98% (HPLC) | 5MG | $111.15 | 2025-07-31 | Buy |
| Usbiological | 462323 | PF-06651600 | 1mg | $319 | 2021-12-16 | Buy |
| Usbiological | 474159 | PF06651600 | 100mg | $2315 | 2021-12-16 | Buy |
Properties
Density :1.272±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO:100.0(Max Conc. mg/mL);350.4(Max Conc. mM)
H2O:5.0(Max Conc. mg/mL);17.5(Max Conc. mM) pka :13.03±0.50(Predicted)
form :powder
color :white to beige
Water Solubility :H2O: 5mg/mL, clear (warmed)
InChI :InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
InChIKey :CBRJPFGIXUFMTM-WDEREUQCSA-N
SMILES :C(N1C[C@H](NC2N=CN=C3NC=CC3=2)CC[C@@H]1C)(=O)C=C
storage temp. :room temp
solubility :DMSO:100.0(Max Conc. mg/mL);350.4(Max Conc. mM)
H2O:5.0(Max Conc. mg/mL);17.5(Max Conc. mM) pka :13.03±0.50(Predicted)
form :powder
color :white to beige
Water Solubility :H2O: 5mg/mL, clear (warmed)
InChI :InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
InChIKey :CBRJPFGIXUFMTM-WDEREUQCSA-N
SMILES :C(N1C[C@H](NC2N=CN=C3NC=CC3=2)CC[C@@H]1C)(=O)C=C
Safety Information
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Description
Ritlecitinib, a dual JAK3/TEC inhibitor, was granted FDA breakthrough status for treating alopecia areata (autoimmune-induced hair loss) in September 2018. Promising phase 3 trial results in alopecia areata were reported by Pfizer in August 2021, placing it in competition with Lilly/Incyte’s Olumiant. It is also used in clinical studies to treat vitiligo, rheumatoid arthritis, Crohn’s disease, and ulcerative colitis. Ritlecitinib achieved high JAK3 selectivity via covalent interaction with a unique cysteine residue (Cys909) in the catalytic domain.More related product prices
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