Robotnikinin
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- $280 - $505.05
- Product name: Robotnikinin
- CAS: 1132653-79-2
- MF: C25H27ClN2O4
- MW: 454.95
- EINECS:
- MDL Number:MFCD28899414
- Synonyms:Robotnikinin;N-(4-chlorobenzyl)-2-((2R,6S,E)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl)acetamide;N-[(4-chlorophenyl)methyl]-2-[(2R,6S,8E)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl]acetamide;1-Oxa-4-azacyclododec-8-ene-6-acetamide, N-[(4-chlorophenyl)methyl]-5,12-dioxo-2-phenyl-, (2R,6S,8E)-;N-[(4-chlorophenyl)methyl]-5,12-dioxo-2R-phenyl-1-oxa-4-azacyclododec-8E-ene-6S-acetamide
4 prices
Selected condition：
Brand
- Adipogen Life Sciences
- American Custom Chemicals Corporation
- Cayman Chemical
- Usbiological
Package
- 1mg
- 5MG
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0069-M001
- Product descriptionRobotnikinin >97%(NMR)
- Packaging1mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0002156
- Product descriptionROBOTNIKININ 97.00%
- Packaging5MG
- Price$505.05
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13204
- Product descriptionRobotnikinin ≥97%
- Packaging1mg
- Price$340
- Updated2024-03-01
- Buy
- ManufacturerUsbiological
- Product number045259
- Product descriptionRobotnikinin
- Packaging1mg
- Price$486
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-0069-M001 | Robotnikinin >97%(NMR) | 1mg | $280 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0002156 | ROBOTNIKININ 97.00% | 5MG | $505.05 | 2021-12-16 | Buy |
| Cayman Chemical | 13204 | Robotnikinin ≥97% | 1mg | $340 | 2024-03-01 | Buy |
| Usbiological | 045259 | Robotnikinin | 1mg | $486 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: Soluble; DMSO: 10 mM; Ethanol: Soluble
form :A crystalline solid
color :White
solubility :DMF: Soluble; DMSO: 10 mM; Ethanol: Soluble
form :A crystalline solid
color :White
Safety Information
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Description
Sonic hedgehog (Shh) is the most widely characterized of the three vertebrate Hedgehog homologs, and is essential for proper embryonic development. Shh binds to its receptor, Patched (Ptch1), resulting in the de-repression of Smoothened. This leads to the activation of Gli2, which regulates the transcription of target genes that include Gli1 and Ptch1. Robotnikinin is the first identified small molecule inhibitor of Shh signaling that acts upstream of Smo, binding directly to Shh with a Kd value of 3.1 μM. Robotnikinin represses Gli-mediated transcription in primary human keratinocytes and synthetic human skin in a concentration-dependent manner.Suppliers and manufacturers
TargetMol Chemicals Inc.
Career Henan Chemica Co
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Shanghai Beckham Medical Technology Co., Ltd
Shanghai EFE Biological Technology Co., Ltd.
Shanghai Changyan Chem & Tech Co., Ltd.
TargetMol Chemicals Inc.
Adipogen Life Sciences
Cayman Chemical Company
