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ChemicalBook >> CAS DataBase List >> (S)-AM1241

(S)-AM1241

(S)-AM1241 price.
  • $63 - $1281
  • Product name: (S)-AM1241
  • CAS: 444912-53-2
  • MF: C22H22IN3O3
  • MW: 503.33
  • EINECS:
  • MDL Number:MFCD18382087
  • Synonyms:(S)-AM1241;(S)-AM1241 Exclusive;ZUHIXXCLLBMBDW-INIZCTEOSA-N;(S)-(-)-1-[(N-Methyl-2-piperidinyl)methyl]-3-(2-iodo-5-nitrobenzoyl)-1H-indole (S)-AM1241;(S) AM1241,(S)AM1241,(S)-AM-1241;Methanone, (2-iodo-5-nitrophenyl)[1-[[(2S)-1-methyl-2-piperidinyl]methyl]-1H-indol-3-yl]-
5 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number1069AH
  • Product description(2-Iodo-5-nitrophenyl)(1-(((2S)-1-methyl-2-piperidinyl)methyl)-1H-indol-3-yl)-methanone
  • Packaging25mg
  • Price$1281
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10490
  • Product description(S)-AM1241 ≥98%
  • Packaging1mg
  • Price$63
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10490
  • Product description(S)-AM1241 ≥98%
  • Packaging5mg
  • Price$275
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10490
  • Product description(S)-AM1241 ≥98%
  • Packaging10mg
  • Price$486
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10490
  • Product description(S)-AM1241 ≥98%
  • Packaging25mg
  • Price$1062
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1069AH (2-Iodo-5-nitrophenyl)(1-(((2S)-1-methyl-2-piperidinyl)methyl)-1H-indol-3-yl)-methanone 25mg $1281 2021-12-16 Buy
Cayman Chemical 10490 (S)-AM1241 ≥98% 1mg $63 2024-03-01 Buy
Cayman Chemical 10490 (S)-AM1241 ≥98% 5mg $275 2024-03-01 Buy
Cayman Chemical 10490 (S)-AM1241 ≥98% 10mg $486 2024-03-01 Buy
Cayman Chemical 10490 (S)-AM1241 ≥98% 25mg $1062 2024-03-01 Buy

Properties

Boiling point :630.7±55.0 °C(Predicted)
Density :1.60±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.3 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml
pka :9.73±0.10(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

(S)-AM1241 binds the peripheral cannabinoid (CB2) receptor from human, rat, and mouse with Ki values of 658, 893, and 577 nM, respectively). It exhibits weak binding for central cannabinoid receptor (CB1) with a Ki value exceeding 10 μM. (S)-1241 is an agonist for CB2 for all three species, but shows greater activity at human CB2 (EC50 = 131 nM) than for either rat or mouse CB2 (EC50 = 785, 2000 nM, respectively). Like the racemate AM1241 , (S)-AM1241 produces antinociception in rats to thermal, but not mechanical, pain. The pain-reducing effect of (S)-AM1241 is blocked by the CB2-specific inhibitor SR 144528, but not by either the CB1-selective inhibitor rimonabant or the opioid receptor blocker naloxone.