SAHA-BPyne
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- $93 - $1139
- Product name: SAHA-BPyne
- CAS: 930772-88-6
- MF: C27H31N3O5
- MW: 477.55
- EINECS:
- MDL Number:
- Synonyms:SAHA-BPyne;N-[4-[4-(hex-5-ynoylamino)benzoyl]phenyl]-N'-hydroxyoctanediamide;Octanediamide, N1-hydroxy-N8-[4-[4-[(1-oxo-5-hexyn-1-yl)amino]benzoyl]phenyl]-;SAHA BPyne,SAHABPyne;N1-Hydroxy-N8-[4-[4-[(1-oxo-5-hexyn-1-yl)amino]benzoyl]phenyl]-octanediamide;SAHA-BPyne(solution in methanol)
3 prices
Selected condition：
Brand
- Cayman Chemical
Package
- 100μg
- 1mg
- 5mg
- ManufacturerCayman Chemical
- Product number10675
- Product descriptionSAHA-BPyne ≥98%
- Packaging100μg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10675
- Product descriptionSAHA-BPyne
- Packaging1mg
- Price$456
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10675
- Product descriptionSAHA-BPyne
- Packaging5mg
- Price$1139
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 10675 | SAHA-BPyne ≥98% | 100μg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 10675 | SAHA-BPyne | 1mg | $456 | 2024-03-01 | Buy |
| Cayman Chemical | 10675 | SAHA-BPyne | 5mg | $1139 | 2024-03-01 | Buy |
Properties
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: 5 mg/ml; Methanol: 5 mg/ml
pka :9.48±0.20(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: 5 mg/ml; Methanol: 5 mg/ml
pka :9.48±0.20(Predicted)
Safety Information
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Description
Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. SAHA-BPyne is a SAHA derivative with a benzophenone crosslinker and an alkyne tag intended to be used for profiling HDAC activities in proteomes and live cells. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions. SAHA-BPyne labels HDAC complex proteins both in proteomes at 100 nM and in live cells at 500 nM and demonstrates an IC50 value of ~3 μM for inhibition of HDAC activity in HeLa cell nuclear lysates in an HDAC activity assay.Suppliers and manufacturers
Shanghai Hongye Biotechnology Co. Ltd
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
MedBioPharmaceutical Technology Inc
TargetMol Chemicals Inc.
Shanghai Yifei Biotechnology Co. , Ltd.
Cayman Chemical Company
Biosynth Biological Technology (Suzhou) Co Ltd
Shanghai Shitang Industrial Co., Ltd.
