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ChemicalBook >> CAS DataBase List >> SB-756050

SB-756050

SB-756050 price.
  • $33 - $1600
  • Product name: SB-756050
  • CAS: 447410-57-3
  • MF: C21H28N2O8S2
  • MW: 500.59
  • EINECS:-0
  • MDL Number:MFCD02585318
  • Synonyms:SB-756050;1,4-bis((3,4-dimethoxyphenyl)sulfonyl)-1,4-diazepane;SB756050;SB 756050;SB-756050;SB-756050, >98%;1H-1,4-Diazepine, 1,4-bis[(3,4-dimethoxyphenyl)sulfonyl]hexahydro-;G protein-coupled Bile Acid Receptor 1,inhibit,TGR5,Inhibitor,SB756050,GPBAR1,G-protein coupled receptor 19,GPCR19
Price11 Properties Safety Information Description
11 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0551CG
  • Product description1,4-Bis[(3,4-dimethoxyphenyl)sulfonyl]-1,4-diazepane
  • Packaging50mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27998
  • Product descriptionSB-756050
  • Packaging10mg
  • Price$33
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27998
  • Product descriptionSB-756050
  • Packaging50mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27998
  • Product descriptionSB-756050
  • Packaging100mg
  • Price$208
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6960
  • Product descriptionSB756050 99.32%
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6960
  • Product descriptionSB756050 99.32%
  • Packaging25mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6960
  • Product descriptionSB756050 99.32%
  • Packaging50mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6960
  • Product descriptionSB756050 99.32%
  • Packaging100mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10470
  • Product descriptionSB756050 >98%
  • Packaging100mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10470
  • Product descriptionSB756050 >98%
  • Packaging250mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10470
  • Product descriptionSB756050 >98%
  • Packaging1g
  • Price$1600
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0551CG 1,4-Bis[(3,4-dimethoxyphenyl)sulfonyl]-1,4-diazepane 50mg $232 2021-12-16 Buy
Cayman Chemical 27998 SB-756050 10mg $33 2024-03-01 Buy
Cayman Chemical 27998 SB-756050 50mg $120 2024-03-01 Buy
Cayman Chemical 27998 SB-756050 100mg $208 2024-03-01 Buy
ChemScene CS-6960 SB756050 99.32% 10mg $75 2021-12-16 Buy
ChemScene CS-6960 SB756050 99.32% 25mg $135 2021-12-16 Buy
ChemScene CS-6960 SB756050 99.32% 50mg $220 2021-12-16 Buy
ChemScene CS-6960 SB756050 99.32% 100mg $350 2021-12-16 Buy
DC Chemicals DC10470 SB756050 >98% 100mg $500 2021-12-16 Buy
DC Chemicals DC10470 SB756050 >98% 250mg $800 2021-12-16 Buy
DC Chemicals DC10470 SB756050 >98% 1g $1600 2021-12-16 Buy

Properties

Boiling point :653.1±65.0 °C(Predicted)
Density :1.328±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.25 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :-6.97±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

SB-756050 is an agonist of the bile acid G protein-coupled receptor TGR5 (EC50 = 1.3 μM for the human receptor). It is selective for TGR5 over the farnesoid X receptor (FXR) and a panel of other receptors, channels, and transporters. SB-756050 (10-100 mg/kg) decreases fasting glucose levels and increases glucose disposal rate and insulin secretion in diabetic Goto Kakizaki rats.

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