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ChemicalBook >> CAS DataBase List >> SB-756050

SB-756050

SB-756050 price.
  • $30 - $4529
  • Product name: SB-756050
  • CAS: 447410-57-3
  • MF: C21H28N2O8S2
  • MW: 500.59
  • EINECS:-0
  • MDL Number:MFCD02585318
  • Synonyms:SB-756050;1,4-bis((3,4-dimethoxyphenyl)sulfonyl)-1,4-diazepane;SB756050;SB 756050;SB-756050;SB-756050, >98%;1H-1,4-Diazepine, 1,4-bis[(3,4-dimethoxyphenyl)sulfonyl]hexahydro-;G protein-coupled Bile Acid Receptor 1,inhibit,TGR5,Inhibitor,SB756050,GPBAR1,G-protein coupled receptor 19,GPCR19;SB756050, 10 mM in DMSO;SB-756050 ，S6741
Price40 Properties Safety Information Description
40 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 5MG
  • 1mlx10mM(inDMSO)
  • 2mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 10mM*1mLinDMSO(Solution)
  • 250mg
  • 500mg
  • 1G
  • 10mM*1mLinDMSO(Solid+Solvent)
  • Manufactureraablocks
  • Product numberAA019G8C
  • Product descriptionSB-756050 ≥95%
  • Packaging50mg
  • Price$132
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA019G8C
  • Product descriptionSB-756050
  • Packaging100mg
  • Price$195
  • Updated2026-05-29
  • Buy
  • Manufactureraablocks
  • Product numberAA019G8C
  • Product descriptionSB-756050 ≥95%
  • Packaging10mg
  • Price$37
  • Updated2026-05-29
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33946
  • Product descriptionSB-756050 98%
  • Packaging100MG
  • Price$225
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33946
  • Product descriptionSB-756050 98%
  • Packaging5MG
  • Price$30
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33946
  • Product descriptionSB-756050 98%
  • Packaging25MG
  • Price$75
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberO33946
  • Product descriptionSB-756050 98%
  • Packaging1G
  • Price$895
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number0551CG
  • Product description1,4-Bis[(3,4-dimethoxyphenyl)sulfonyl]-1,4-diazepane
  • Packaging50mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S6741
  • Product descriptionSB-756050 99.08%
  • Packaging5mg
  • Price$378
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-102016
  • Product descriptionSB756050 98.89%
  • Packaging50mg
  • Price$171
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-102016
  • Product descriptionSB756050 98.89%
  • Packaging5mg
  • Price$48
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-102016
  • Product descriptionSB756050 98.89%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$50
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-102016
  • Product descriptionSB756050 98.89%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$53
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-102016
  • Product descriptionSB756050 98.89%
  • Packaging25mg
  • Price$114
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberSLK-S6741
  • Product descriptionSB-756050 99.08%
  • Packaging2mg
  • Price$131
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-102016
  • Product descriptionSB756050 98.89%
  • Packaging10mg
  • Price$67
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA019G8C SB-756050 ≥95% 50mg $132 2026-05-29 Buy
aablocks AA019G8C SB-756050 100mg $195 2026-05-29 Buy
aablocks AA019G8C SB-756050 ≥95% 10mg $37 2026-05-29 Buy
ACHEMBLOCK O33946 SB-756050 98% 100MG $225 2026-05-27 Buy
ACHEMBLOCK O33946 SB-756050 98% 5MG $30 2026-05-27 Buy
ACHEMBLOCK O33946 SB-756050 98% 25MG $75 2026-05-27 Buy
ACHEMBLOCK O33946 SB-756050 98% 1G $895 2026-05-27 Buy
AK Scientific 0551CG 1,4-Bis[(3,4-dimethoxyphenyl)sulfonyl]-1,4-diazepane 50mg $232 2021-12-16 Buy
Arctom SLK-S6741 SB-756050 99.08% 5mg $378 2026-05-26 Buy
Arctom HY-102016 SB756050 98.89% 50mg $171 2026-05-26 Buy
Arctom HY-102016 SB756050 98.89% 5mg $48 2026-05-26 Buy
Arctom HY-102016 SB756050 98.89% 10mM*1mLinDMSO(Solid+Solvent) $50 2026-05-26 Buy
Arctom HY-102016 SB756050 98.89% 10mM*1mLinDMSO(Solution) $53 2026-05-26 Buy
Arctom HY-102016 SB756050 98.89% 25mg $114 2026-05-26 Buy
Arctom SLK-S6741 SB-756050 99.08% 2mg $131 2026-05-26 Buy
Arctom HY-102016 SB756050 98.89% 10mg $67 2026-05-26 Buy
Next Last

Properties

Boiling point :653.1±65.0 °C(Predicted)
Density :1.328±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.25 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :-6.97±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

SB-756050 is an agonist of the bile acid G protein-coupled receptor TGR5 (EC50 = 1.3 μM for the human receptor). It is selective for TGR5 over the farnesoid X receptor (FXR) and a panel of other receptors, channels, and transporters. SB-756050 (10-100 mg/kg) decreases fasting glucose levels and increases glucose disposal rate and insulin secretion in diabetic Goto Kakizaki rats.

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Suppliers and manufacturers

Dalian Meilun Biotech Co., Ltd. MedChemexpress LLC Shanghai JiYi Biotechnology Co. Ltd. Shanghai YuanYe Biotechnology Co., Ltd. Tianjin Kailiqi Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai Chaolan Chemical Technology Center Amadis Chemical Company Limited Medi-tech Bioscientific Co., Ltd. Twochem Co.Ltd.