SJA6017
|
- $73 - $1429.6
- Product name: SJA6017
- CAS: 190274-53-4
- MF: C17H25FN2O4S
- MW: 372.45
- EINECS:
- MDL Number:MFCD00954660
- Synonyms:N-(4-FLUOROPHENYLSULFONYL)-L-VALYL-L-LEUCINAL;4-FLUORO-BENZENESULFONYL-VAL-LEU-ALDEHYDE;4-FLUORO-BENZENESULFONYL-VAL-L-LEUCINAL;CALPAIN INHIBITOR VI;SJA6017, 4-Fluoro-benzenesulfonyl-Val-L-leucinal;SJA6017;Calpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde;Calpain Inhibitor 4
7 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
Package
- 500ug
- 1mg
- 5MG
- 10mg
- ManufacturerAK Scientific
- Product number0719DA
- Product descriptionCalpainInhibitorVI
- Packaging1mg
- Price$179
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000054
- Product descriptionSJA6017 95.00%
- Packaging1MG
- Price$722.8
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000054
- Product descriptionSJA6017 95.00%
- Packaging5MG
- Price$1303.53
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC111099
- Product descriptionCalpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde
- Packaging500ug
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC111099
- Product descriptionCalpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde
- Packaging1mg
- Price$236
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC111099
- Product descriptionCalpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde
- Packaging10mg
- Price$1429.6
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23942
- Product descriptionCalpain Inhibitor VI ≥95%
- Packaging1mg
- Price$73
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0719DA | CalpainInhibitorVI | 1mg | $179 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000054 | SJA6017 95.00% | 1MG | $722.8 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000054 | SJA6017 95.00% | 5MG | $1303.53 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC111099 | Calpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde | 500ug | $135 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC111099 | Calpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde | 1mg | $236 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC111099 | Calpain Inhibitor VI 4-Fluoro-benzenesulfonyl-Val-Leu-aldehyde | 10mg | $1429.6 | 2021-12-16 | Buy |
| Cayman Chemical | 23942 | Calpain Inhibitor VI ≥95% | 1mg | $73 | 2024-03-01 | Buy |
Properties
Density :1.185±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: 5 mg/ml
form :A lyophilized solid
pka :9.04±0.50(Predicted)
color :white
storage temp. :Store at -20°C
solubility :DMSO: 5 mg/ml
form :A lyophilized solid
pka :9.04±0.50(Predicted)
color :white
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases μ-calpain (calpain-1; IC50 = 7.5 nM) and m-calpain (calpain-2; IC50 = 78 nM). It also inhibits cathepsins B and L (IC50s = 15 and 1.6 nM, respectively). It is selective for these calpains and cathepsins over other cysteine and serine proteases, factor VIIa, factor Xa, trypsin, chymotrypsin, and proteasome. In an in vitro porcine model of cataract, calpain inhibitor VI decreases the degree of cataract by 40% when used at a concentration of 0.8 μM. It also prevents cataract formation induced by selenite in rats when administered at a dose of 100 mg/kg for 4 days. Calpain inhibitor VI improves functional outcome and reduces apoptotic cell death in a rat model of spinal cord injury.More related product prices
Related product price
- SJA6017
$73-1429.6
