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ChemicalBook >> CAS DataBase List >> SM-164

SM-164

SM-164 price.
  • $99 - $4000
  • Product name: SM-164
  • CAS: 957135-43-2
  • MF: C62H84N14O6
  • MW: 1121.45
  • EINECS:
  • MDL Number:MFCD28167763
  • Synonyms:SM-164;(3S,3'S,6S,6'S,10aS,10'aS)-N,N'-[1,4-Phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-pyrrolo[1,2-a]azocine-3-carboxamide;SM 164 (pharmaceutical);SM-164;SM 164;SM164;(S,3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-(1,1'-(4,4'-(1,4-phenylene)bis(butane-4,1-diyl))bis(1H-1,2,3-triazole-4,1-diyl))bis(phenylmethylene))bis(6-((S)-2-(2-methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide);SM 164; SM164;Pyrrolo[1,2-a]azocine-3-carboxamide, N,N'-[1,4-phenylenebis[4,1-butanediyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethylene]]]bis[decahydro-6-[[(2S)-2-(methylamino)-1-oxopropyl]amino]-5-oxo-, (3S,3'S,6S,6'S,10aS,10'aS)-;Apoptosis,inhibit,SM164,IAP,Inhibitor,SM-164,SM 164
Price17 Properties Safety Information Description
17 prices
Selected condition：
Brand
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 10mM(in 1mL DMSO)
  • 500μg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • ManufacturerAmbeed
  • Product numberA203870
  • Product description(3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+%
  • Packaging1mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203870
  • Product description(3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+%
  • Packaging5mg
  • Price$265
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203870
  • Product description(3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+%
  • Packaging10mg
  • Price$432
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203870
  • Product description(3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+%
  • Packaging25mg
  • Price$738
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203870
  • Product description(3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+%
  • Packaging50mg
  • Price$959
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA203870
  • Product description(3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+%
  • Packaging100mg
  • Price$1247
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8815
  • Product descriptionSM-164
  • Packaging5mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8815
  • Product descriptionSM-164
  • Packaging10mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8815
  • Product descriptionSM-164
  • Packaging10mM(in 1mL DMSO)
  • Price$630
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8815
  • Product descriptionSM-164
  • Packaging25mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8815
  • Product descriptionSM-164
  • Packaging200mg
  • Price$4000
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28632
  • Product descriptionSM-164
  • Packaging500μg
  • Price$99
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28632
  • Product descriptionSM-164
  • Packaging1mg
  • Price$188
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000074
  • Product descriptionSM-164 98+%
  • Packaging5mg
  • Price$296
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000074
  • Product descriptionSM-164 98+%
  • Packaging10mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8490
  • Product descriptionSM-164 >98%
  • Packaging50mg
  • Price$750
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A203870 (3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+% 1mg $111 2021-12-16 Buy
Ambeed A203870 (3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+% 5mg $265 2021-12-16 Buy
Ambeed A203870 (3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+% 10mg $432 2021-12-16 Buy
Ambeed A203870 (3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+% 25mg $738 2021-12-16 Buy
Ambeed A203870 (3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+% 50mg $959 2021-12-16 Buy
Ambeed A203870 (3S,3'S,6S,6'S,10aS,10a'S)-N,N'-((1S,1'S)-((1,4-Phenylenebis(butane-4,1-diyl))bis(1H-1,2,3-triazole-1,4-diyl))bis(phenylmethylene))bis(6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide) 98+% 100mg $1247 2021-12-16 Buy
ApexBio Technology A8815 SM-164 5mg $350 2021-12-16 Buy
ApexBio Technology A8815 SM-164 10mg $500 2021-12-16 Buy
ApexBio Technology A8815 SM-164 10mM(in 1mL DMSO) $630 2021-12-16 Buy
ApexBio Technology A8815 SM-164 25mg $1000 2021-12-16 Buy
ApexBio Technology A8815 SM-164 200mg $4000 2021-12-16 Buy
Cayman Chemical 28632 SM-164 500μg $99 2024-03-01 Buy
Cayman Chemical 28632 SM-164 1mg $188 2024-03-01 Buy
Crysdot CD31000074 SM-164 98+% 5mg $296 2021-12-16 Buy
Crysdot CD31000074 SM-164 98+% 10mg $480 2021-12-16 Buy
DC Chemicals DC8490 SM-164 >98% 50mg $750 2021-12-16 Buy
Next Last

Properties

Density :1.33±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (50 mg/ml)
form :solid
pka :12.62±0.40(Predicted)
color :White to pale-yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

SM-164 (957135-43-2) is a cell-permeable Smac (DIABLO) mimetic that inhibits caspase blockers XIAP, cIAP1, and cIAP2 (Ki = 36, <1, and <1.9 nM), thus inducing apoptosis.1-3 SM-164 sensitizes cancer cells to DNA damaging agents.4 It also prevents binding of Hsp70 to XIAP.5 At high concentrations, it causes lytic cell death that is neither apoptosis nor necroptosis.6

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