SM 7368
|
- $89 - $504
- Product name: SM 7368
- CAS: 380623-76-7
- MF: C10H5ClN4O5S
- MW: 328.69
- EINECS:
- MDL Number:MFCD00834007
- Synonyms:3-Chloro-4-nitro-N-(5-nitro-2-thiazolyl)-benzamide;SM 7368;SM-7368;NFκB Activation Inhibitor III;NF-κB Activation Inhibitor III - CAS 380623-76-7 - Calbiochem;3-Chloro-4-nitro-N-(5-nitrothiazol-2-yl)benzamide;Matrix,Nuclear factor-kappaB,TNF-α,MMP-9,Inhibitor,SM-7368,p38 MAPK,Nuclear factor-κB,SM 7368,MAPK,NF-κB,SM7368,MMP,Invasion,inhibit,Matrix metalloproteinases;Benzamide, 3-chloro-4-nitro-N-(5-nitro-2-thiazolyl)-
8 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- TRC
Package
- 5mg
- 25mg
- ManufacturerAK Scientific
- Product number4756BB
- Product description3-Chloro-4-nitro-N-(5-nitro-2-thiazolyl)-benzamide
- Packaging5mg
- Price$197
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3559
- Product descriptionNF-κB Activation Inhibitor III
- Packaging5mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3559
- Product descriptionNF-κB Activation Inhibitor III
- Packaging25mg
- Price$406
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19083
- Product descriptionNF-κB Activation Inhibitor III ≥99%
- Packaging5mg
- Price$89
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19083
- Product descriptionNF-κB Activation Inhibitor III ≥99%
- Packaging25mg
- Price$374
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number481411
- Product descriptionNF-κB Activation Inhibitor III
- Packaging5mg
- Price$176
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0454
- Product descriptionSM-7368 ≥98% (HPLC)
- Packaging25mg
- Price$504
- Updated2022-05-15
- Buy
- ManufacturerTRC
- Product numberN392518
- Product descriptionNFkappaBActivationInhibitorIII
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4756BB | 3-Chloro-4-nitro-N-(5-nitro-2-thiazolyl)-benzamide | 5mg | $197 | 2021-12-16 | Buy |
| ApexBio Technology | C3559 | NF-κB Activation Inhibitor III | 5mg | $96 | 2021-12-16 | Buy |
| ApexBio Technology | C3559 | NF-κB Activation Inhibitor III | 25mg | $406 | 2021-12-16 | Buy |
| Cayman Chemical | 19083 | NF-κB Activation Inhibitor III ≥99% | 5mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 19083 | NF-κB Activation Inhibitor III ≥99% | 25mg | $374 | 2024-03-01 | Buy |
| Sigma-Aldrich | 481411 | NF-κB Activation Inhibitor III | 5mg | $176 | 2025-07-31 | Buy |
| Sigma-Aldrich | SML0454 | SM-7368 ≥98% (HPLC) | 25mg | $504 | 2022-05-15 | Buy |
| TRC | N392518 | NFkappaBActivationInhibitorIII | 5mg | $90 | 2021-12-16 | Buy |
Properties
Density :1.761±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
form :powder
pka :5.18±0.50(Predicted)
color :white to beige
InChI :1S/C10H5ClN4O5S/c11-6-3-5(1-2-7(6)14(17)18)9(16)13-10-12-4-8(21-10)15(19)20/h1-4H,(H,12,13,16)
InChIKey :XCHLNGBTHLJLFG-UHFFFAOYSA-N
SMILES :[s]1c(ncc1[N+](=O)[O-])NC(=O)c2cc(c(cc2)[N+](=O)[O-])Cl
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
form :powder
pka :5.18±0.50(Predicted)
color :white to beige
InChI :1S/C10H5ClN4O5S/c11-6-3-5(1-2-7(6)14(17)18)9(16)13-10-12-4-8(21-10)15(19)20/h1-4H,(H,12,13,16)
InChIKey :XCHLNGBTHLJLFG-UHFFFAOYSA-N
SMILES :[s]1c(ncc1[N+](=O)[O-])NC(=O)c2cc(c(cc2)[N+](=O)[O-])Cl
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Matrix metalloproteinase-9 (MMP-9), via activation by TNF-α, plays a key role in tumor invasion and metastasis. NF-κB activation inhibitor III is a compound that inhibits TNF-α-induced MMP-9 protein expression (maximal effect at 10 μM) by blocking NF-κB activity in HT1080 human fibrosarcoma cells. It has been used to disrupt NF-κB signaling in order to study the role of syndecans in mediating extracellular matrix integrity.Related product price
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