SMI-16a
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- $15 - $1740
- Product name: SMI-16a
- CAS: 587852-28-6
- MF: C13H13NO3S
- MW: 263.31
- EINECS:-0
- MDL Number:MFCD31382191
- Synonyms:SMI-16a;PIM1/2 Kinase Inhibitor VI;SMI-16a(PIM1/2 Kinase Inhibitor VI);SMI-16A;SMI 16A;SMI16A;2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-;SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases;5-(4-propoxybenzylidene)thiazolidine-2,4-dione;SMI-16a, 10 mM in DMSO
37 prices
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Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- Arctom
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1G
- 5G
- 5 mg
- Manufactureraablocks
- Product numberAA01EAYW
- Product descriptionSMI-16a 99%
- Packaging1mg
- Price$15
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYW
- Product descriptionSMI-16a 99%
- Packaging5mg
- Price$35
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYW
- Product descriptionSMI-16a 99%
- Packaging10mg
- Price$61
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYW
- Product descriptionSMI-16a 99%
- Packaging25mg
- Price$103
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYW
- Product descriptionSMI-16a 99%
- Packaging50mg
- Price$174
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EAYW
- Product descriptionSMI-16a 99
- Packaging100mg
- Price$318
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65714
- Product description(E)-5-(4-propoxybenzylidene)thiazolidine-2,4-dione 98%
- Packaging250MG
- Price$205
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65714
- Product description(E)-5-(4-propoxybenzylidene)thiazolidine-2,4-dione 98%
- Packaging1G
- Price$435
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65714
- Product description(E)-5-(4-propoxybenzylidene)thiazolidine-2,4-dione 98%
- Packaging5G
- Price$1740
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-P0110-M010
- Product description5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione ≥95%(HPLC)
- Packaging10mg
- Price$158
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-P0110-M050
- Product description5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione ≥95%(HPLC)
- Packaging50mg
- Price$631
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-P0110-M005
- Product description5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione ≥95%(HPLC)
- Packaging5mg
- Price$99
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberSLK-S6497
- Product descriptionSMI-16a 99.85%
- Packaging5mg
- Price$140
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberBD-A310740
- Product descriptionSMI-16a 99%
- Packaging25mg
- Price$106
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberBD-A310740
- Product descriptionSMI-16a 99%
- Packaging10mg
- Price$62
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberBD-A310740
- Product descriptionSMI-16a 99%
- Packaging1mg
- Price$15
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01EAYW | SMI-16a 99% | 1mg | $15 | 2026-05-30 | Buy |
| aablocks | AA01EAYW | SMI-16a 99% | 5mg | $35 | 2026-05-30 | Buy |
| aablocks | AA01EAYW | SMI-16a 99% | 10mg | $61 | 2026-05-30 | Buy |
| aablocks | AA01EAYW | SMI-16a 99% | 25mg | $103 | 2026-05-30 | Buy |
| aablocks | AA01EAYW | SMI-16a 99% | 50mg | $174 | 2026-05-30 | Buy |
| aablocks | AA01EAYW | SMI-16a 99 | 100mg | $318 | 2026-05-30 | Buy |
| ACHEMBLOCK | Q65714 | (E)-5-(4-propoxybenzylidene)thiazolidine-2,4-dione 98% | 250MG | $205 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65714 | (E)-5-(4-propoxybenzylidene)thiazolidine-2,4-dione 98% | 1G | $435 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65714 | (E)-5-(4-propoxybenzylidene)thiazolidine-2,4-dione 98% | 5G | $1740 | 2026-05-27 | Buy |
| Adipogen Life Sciences | CDX-P0110-M010 | 5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione ≥95%(HPLC) | 10mg | $158 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-P0110-M050 | 5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione ≥95%(HPLC) | 50mg | $631 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-P0110-M005 | 5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione ≥95%(HPLC) | 5mg | $99 | 2026-05-06 | Buy |
| Arctom | SLK-S6497 | SMI-16a 99.85% | 5mg | $140 | 2026-05-26 | Buy |
| Arctom | BD-A310740 | SMI-16a 99% | 25mg | $106 | 2026-05-26 | Buy |
| Arctom | BD-A310740 | SMI-16a 99% | 10mg | $62 | 2026-05-26 | Buy |
| Arctom | BD-A310740 | SMI-16a 99% | 1mg | $15 | 2026-05-26 | Buy |
Properties
Melting point :186.3-188.4 °C
Density :1.303±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
form :A solid
pka :7.27±0.20(Predicted)
color :Light yellow to yellow
InChI :1S/C13H13NO3S/c1-2-7-17-10-5-3-9(4-6-10)8-11-12(15)14-13(16)18-11/h3-6,8H,2,7H2,1H3,(H,14,15,16)
InChIKey :GBWOSXZUTXXXQF-UHFFFAOYSA-N
SMILES :S1C(=O)NC(=O)C1=Cc2ccc(cc2)OCCC
Density :1.303±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
form :A solid
pka :7.27±0.20(Predicted)
color :Light yellow to yellow
InChI :1S/C13H13NO3S/c1-2-7-17-10-5-3-9(4-6-10)8-11-12(15)14-13(16)18-11/h3-6,8H,2,7H2,1H3,(H,14,15,16)
InChIKey :GBWOSXZUTXXXQF-UHFFFAOYSA-N
SMILES :S1C(=O)NC(=O)C1=Cc2ccc(cc2)OCCC
Safety Information
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Description
SMI-16a is a Pim-1 kinase inhibitor (IC50 = 63 nM). It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 μM) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G1 phase in DU145 cells.Related product price
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