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ChemicalBook >> CAS DataBase List >> SMI-16a

SMI-16a

SMI-16a price.
  • $59 - $1700
  • Product name: SMI-16a
  • CAS: 587852-28-6
  • MF: C13H13NO3S
  • MW: 263.31
  • EINECS:-0
  • MDL Number:MFCD31382191
  • Synonyms:SMI-16a;PIM1/2 Kinase Inhibitor VI;SMI-16a(PIM1/2 Kinase Inhibitor VI);SMI-16A;SMI 16A;SMI16A;2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-;SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases;5-(4-propoxybenzylidene)thiazolidine-2,4-dione;SMI-16a, 10 mM in DMSO
14 prices
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Brand
  • Adipogen Life Sciences
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-P0110-M010
  • Product description5-[(4-Propyloxyphenyl)methylene]2,4-thiazolidinedione ≥95%(HPLC)
  • Packaging10mg
  • Price$141
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29456
  • Product descriptionSMI-16a
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29456
  • Product descriptionSMI-16a
  • Packaging10mg
  • Price$166
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29456
  • Product descriptionSMI-16a
  • Packaging25mg
  • Price$365
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM253842
  • Product descriptionSMI-16a 98%
  • Packaging50mg
  • Price$619
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6913
  • Product descriptionSMI-16a 99.70%
  • Packaging50mg
  • Price$828
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6913
  • Product descriptionSMI-16a 99.70%
  • Packaging25mg
  • Price$468
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6913
  • Product descriptionSMI-16a 99.70%
  • Packaging10mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6913
  • Product descriptionSMI-16a 99.70%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00003261
  • Product descriptionSMI-16a(PIM1/2KinaseInhibitorVI) 98+%
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00003261
  • Product descriptionSMI-16a(PIM1/2KinaseInhibitorVI) 98+%
  • Packaging50mg
  • Price$277
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00003261
  • Product descriptionSMI-16a(PIM1/2KinaseInhibitorVI) 98+%
  • Packaging100mg
  • Price$416
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10514
  • Product descriptionSMI-16a >98%
  • Packaging100mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10514
  • Product descriptionSMI-16a >98%
  • Packaging1g
  • Price$1700
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-P0110-M010 5-[(4-Propyloxyphenyl)methylene]2,4-thiazolidinedione ≥95%(HPLC) 10mg $141 2021-12-16 Buy
Cayman Chemical 29456 SMI-16a 5mg $93 2024-03-01 Buy
Cayman Chemical 29456 SMI-16a 10mg $166 2024-03-01 Buy
Cayman Chemical 29456 SMI-16a 25mg $365 2024-03-01 Buy
Chemenu CM253842 SMI-16a 98% 50mg $619 2021-12-16 Buy
ChemScene CS-6913 SMI-16a 99.70% 50mg $828 2021-12-16 Buy
ChemScene CS-6913 SMI-16a 99.70% 25mg $468 2021-12-16 Buy
ChemScene CS-6913 SMI-16a 99.70% 10mg $216 2021-12-16 Buy
ChemScene CS-6913 SMI-16a 99.70% 5mg $120 2021-12-16 Buy
Crysdot CD00003261 SMI-16a(PIM1/2KinaseInhibitorVI) 98+% 10mg $59 2021-12-16 Buy
Crysdot CD00003261 SMI-16a(PIM1/2KinaseInhibitorVI) 98+% 50mg $277 2021-12-16 Buy
Crysdot CD00003261 SMI-16a(PIM1/2KinaseInhibitorVI) 98+% 100mg $416 2021-12-16 Buy
DC Chemicals DC10514 SMI-16a >98% 100mg $500 2021-12-16 Buy
DC Chemicals DC10514 SMI-16a >98% 1g $1700 2021-12-16 Buy

Properties

Melting point :186.3-188.4 °C
Density :1.303±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
form :A solid
pka :7.27±0.20(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

SMI-16a is a Pim-1 kinase inhibitor (IC50 = 63 nM). It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 μM) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G1 phase in DU145 cells.