SMI-16a
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- $59 - $1700
- Product name: SMI-16a
- CAS: 587852-28-6
- MF: C13H13NO3S
- MW: 263.31
- EINECS:-0
- MDL Number:MFCD31382191
- Synonyms:SMI-16a;PIM1/2 Kinase Inhibitor VI;SMI-16a(PIM1/2 Kinase Inhibitor VI);SMI-16A;SMI 16A;SMI16A;2,4-Thiazolidinedione, 5-[(4-propoxyphenyl)methylene]-;SMI-16a,SMI 16a,inhibit,SMI16a,Pim,Inhibitor,Pim kinases;5-(4-propoxybenzylidene)thiazolidine-2,4-dione;SMI-16a, 10 mM in DMSO
14 prices
Selected condition:
Brand
- Adipogen Life Sciences
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberCDX-P0110-M010
- Product description5-[(4-Propyloxyphenyl)methylene]2,4-thiazolidinedione ≥95%(HPLC)
- Packaging10mg
- Price$141
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29456
- Product descriptionSMI-16a
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29456
- Product descriptionSMI-16a
- Packaging10mg
- Price$166
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29456
- Product descriptionSMI-16a
- Packaging25mg
- Price$365
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM253842
- Product descriptionSMI-16a 98%
- Packaging50mg
- Price$619
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6913
- Product descriptionSMI-16a 99.70%
- Packaging50mg
- Price$828
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6913
- Product descriptionSMI-16a 99.70%
- Packaging25mg
- Price$468
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6913
- Product descriptionSMI-16a 99.70%
- Packaging10mg
- Price$216
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6913
- Product descriptionSMI-16a 99.70%
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD00003261
- Product descriptionSMI-16a(PIM1/2KinaseInhibitorVI) 98+%
- Packaging10mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD00003261
- Product descriptionSMI-16a(PIM1/2KinaseInhibitorVI) 98+%
- Packaging50mg
- Price$277
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD00003261
- Product descriptionSMI-16a(PIM1/2KinaseInhibitorVI) 98+%
- Packaging100mg
- Price$416
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10514
- Product descriptionSMI-16a >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10514
- Product descriptionSMI-16a >98%
- Packaging1g
- Price$1700
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | CDX-P0110-M010 | 5-[(4-Propyloxyphenyl)methylene]2,4-thiazolidinedione ≥95%(HPLC) | 10mg | $141 | 2021-12-16 | Buy |
Cayman Chemical | 29456 | SMI-16a | 5mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 29456 | SMI-16a | 10mg | $166 | 2024-03-01 | Buy |
Cayman Chemical | 29456 | SMI-16a | 25mg | $365 | 2024-03-01 | Buy |
Chemenu | CM253842 | SMI-16a 98% | 50mg | $619 | 2021-12-16 | Buy |
ChemScene | CS-6913 | SMI-16a 99.70% | 50mg | $828 | 2021-12-16 | Buy |
ChemScene | CS-6913 | SMI-16a 99.70% | 25mg | $468 | 2021-12-16 | Buy |
ChemScene | CS-6913 | SMI-16a 99.70% | 10mg | $216 | 2021-12-16 | Buy |
ChemScene | CS-6913 | SMI-16a 99.70% | 5mg | $120 | 2021-12-16 | Buy |
Crysdot | CD00003261 | SMI-16a(PIM1/2KinaseInhibitorVI) 98+% | 10mg | $59 | 2021-12-16 | Buy |
Crysdot | CD00003261 | SMI-16a(PIM1/2KinaseInhibitorVI) 98+% | 50mg | $277 | 2021-12-16 | Buy |
Crysdot | CD00003261 | SMI-16a(PIM1/2KinaseInhibitorVI) 98+% | 100mg | $416 | 2021-12-16 | Buy |
DC Chemicals | DC10514 | SMI-16a >98% | 100mg | $500 | 2021-12-16 | Buy |
DC Chemicals | DC10514 | SMI-16a >98% | 1g | $1700 | 2021-12-16 | Buy |
Properties
Melting point :186.3-188.4 °C
Density :1.303±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
form :A solid
pka :7.27±0.20(Predicted)
color :Light yellow to yellow
Density :1.303±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Ethanol:3.0(Max Conc. mg/mL);11.39(Max Conc. mM)
form :A solid
pka :7.27±0.20(Predicted)
color :Light yellow to yellow
Safety Information
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Description
SMI-16a is a Pim-1 kinase inhibitor (IC50 = 63 nM). It is selective for Pim-1 over a panel of 60 kinases. SMI-16a (5 μM) inhibits phosphorylation of the Pim-1 target protein Bad in DU145-Pim cells and inhibits the growth of PC3, DU145, LNCaP, K562, and MV4-11 cancer cells. It induces apoptosis and cell cycle arrest at the G1 phase in DU145 cells.Related product price
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