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ChemicalBook >> CAS DataBase List >> STATIL

STATIL

STATIL price.
  • $11 - $1971
  • Product name: STATIL
  • CAS: 72702-95-5
  • MF: C17H12BrFN2O3
  • MW: 391.19
  • EINECS:
  • MDL Number:MFCD00204117
  • Synonyms:3-(4-BROMO-2-FLUOROBENZYL)-4-OXO-3H-PHTHALAZIN-1-YL]ACETIC ACID (STATIL);3-[(4-Bromo-2-fluorophenyl)methyl]-3,4-dihydro-4-oxo-1-phthalazineacetic acid;ICI-128436;ICI-plc;MK-538;2-(3-(4-broMo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid;Ponalrestat Statil;STATIL
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  • 10mM*1mLinDMSO(Solution)
  • 5g
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  • 10mM*1mLinDMSO(Solid+Solvent)
  • Manufactureraablocks
  • Product numberAA005PQT
  • Product description2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 98%
  • Packaging1mg
  • Price$11
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005PQT
  • Product description2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid ≥98%
  • Packaging5mg
  • Price$36
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005PQT
  • Product description2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid ≥95%
  • Packaging10mg
  • Price$50
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005PQT
  • Product description2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid
  • Packaging25mg
  • Price$72
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005PQT
  • Product description2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 97%
  • Packaging100mg
  • Price$113
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005PQT
  • Product description2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 97%
  • Packaging1g
  • Price$507
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005PQT
  • Product description2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 97%
  • Packaging250mg
  • Price$207
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA005PQT
  • Product description2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 97%
  • Packaging5g
  • Price$1508
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberM15435
  • Product descriptionStatil 98%
  • Packaging1G
  • Price$645
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberM15435
  • Product descriptionStatil 98%
  • Packaging250MG
  • Price$215
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number3829AL
  • Product descriptionStatil
  • Packaging1g
  • Price$1971
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number72702955
  • Product description2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)aceticacid
  • Packaging1g
  • Price$1483.2
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number72702955
  • Product description2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)aceticacid
  • Packaging250mg
  • Price$599.04
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA417818
  • Product descriptionPonalrestat 98%
  • Packaging100mg
  • Price$108
  • Updated2026-06-05
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  • ManufacturerAmbeed
  • Product numberA417818
  • Product descriptionPonalrestat 98%
  • Packaging50mg
  • Price$84
  • Updated2026-06-05
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  • ManufacturerAmbeed
  • Product numberA417818
  • Product descriptionPonalrestat 98%
  • Packaging10mg
  • Price$36
  • Updated2026-06-05
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA005PQT 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 98% 1mg $11 2026-05-28 Buy
aablocks AA005PQT 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid ≥98% 5mg $36 2026-05-28 Buy
aablocks AA005PQT 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid ≥95% 10mg $50 2026-05-28 Buy
aablocks AA005PQT 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 25mg $72 2026-05-28 Buy
aablocks AA005PQT 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 97% 100mg $113 2026-05-28 Buy
aablocks AA005PQT 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 97% 1g $507 2026-05-28 Buy
aablocks AA005PQT 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 97% 250mg $207 2026-05-28 Buy
aablocks AA005PQT 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetic acid 97% 5g $1508 2026-05-28 Buy
ACHEMBLOCK M15435 Statil 98% 1G $645 2026-05-27 Buy
ACHEMBLOCK M15435 Statil 98% 250MG $215 2026-05-27 Buy
AK Scientific 3829AL Statil 1g $1971 2021-12-16 Buy
Alichem 72702955 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)aceticacid 1g $1483.2 2021-12-16 Buy
Alichem 72702955 2-(3-(4-Bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)aceticacid 250mg $599.04 2021-12-16 Buy
Ambeed A417818 Ponalrestat 98% 100mg $108 2026-06-05 Buy
Ambeed A417818 Ponalrestat 98% 50mg $84 2026-06-05 Buy
Ambeed A417818 Ponalrestat 98% 10mg $36 2026-06-05 Buy

Properties

Melting point :184-186℃ (DEC.)
Density :1.60
storage temp. :Store at RT
solubility :DMF: 2 mg/mL; DMSO: 2 mg/mL; Ethanol: 2 mg/mL; PBS (pH 7.2): 0.2 mg/mL
form :A crystalline solid
color :White to off-white
InChI :InChI=1S/C17H12BrFN2O3/c18-11-6-5-10(14(19)7-11)9-21-17(24)13-4-2-1-3-12(13)15(20-21)8-16(22)23/h1-7H,8-9H2,(H,22,23)
InChIKey :LKBFFDOJUKLQNY-UHFFFAOYSA-N
SMILES :C12C=CC=CC=1C(=O)N(CC1=CC=C(Br)C=C1F)N=C2CC(=O)O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Statil is an aldose reductase inhibitor that blocks the conversion of glucose to sorbitol. It demonstrates selectivity for aldose reductase 2 over aldose reductase 1 with Ki values of 7.7 nM and 60 μM, respectively. Statil has been shown to prevent diabetes-induced alterations of the cardiovascular system in 14-day streptozotocin-diabetic rats. Aldose reductase inhibition by statil has also been used to impair the synthesis of prostaglandin F2α by human cultured preadipocytes.

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