SULINDAC SULFONE
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- $31 - $461
- Product name: SULINDAC SULFONE
- CAS: 59864-04-9
- MF: C20H17FO4S
- MW: 372.41
- EINECS:
- MDL Number:MFCD01317811
- Synonyms:SULINDAC SULFONE;(Z)-5-FLUORO-2-METHYL-1[P-(METHYLSULFONYL)BENZYLIDENE]INDENE-3-ACETIC ACID;APTOSYN;EXISULIND;FGN-1;1H-Indene-3-acetic acid, 5-fluoro-2-methy L-1-((4-(methylsulfonyl)phenyl)methylene)-;5-Fluoro-2-methy L-1-((4-(methylsulfonyl)phenyl)methylene)-1H-indene-3-acetic acid;2-[(3Z)-6-Fluoro-2-Methyl-3-[(4-Methylsulfonylphenyl)Methylene]-1-Indenyl]Acetic Acid
9 prices
Selected condition：
Brand
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 100mg
- ManufacturerApexBio Technology
- Product numberC3453
- Product descriptionSulindac sulfone
- Packaging5mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3453
- Product descriptionSulindac sulfone
- Packaging10mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16805
- Product descriptionSulindac sulfone ≥98%
- Packaging1mg
- Price$31
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number16805
- Product descriptionSulindac sulfone ≥98%
- Packaging5mg
- Price$46
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16805
- Product descriptionSulindac sulfone ≥98%
- Packaging10mg
- Price$88
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16805
- Product descriptionSulindac sulfone ≥98%
- Packaging25mg
- Price$173
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberS1438
- Product descriptionSulindac sulfone ≥94% (HPLC), (solid or powder)
- Packaging5mg
- Price$120
- Updated2023-06-20
- Buy
- ManufacturerSigma-Aldrich
- Product numberS1438
- Product descriptionSulindac sulfone ≥94% (HPLC), (solid or powder)
- Packaging25mg
- Price$461
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberS699323
- Product descriptionSulindac sulfone
- Packaging100mg
- Price$145
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | C3453 | Sulindac sulfone | 5mg | $35 | 2021-12-16 | Buy |
| ApexBio Technology | C3453 | Sulindac sulfone | 10mg | $40 | 2021-12-16 | Buy |
| Cayman Chemical | 16805 | Sulindac sulfone ≥98% | 1mg | $31 | 2023-06-20 | Buy |
| Cayman Chemical | 16805 | Sulindac sulfone ≥98% | 5mg | $46 | 2024-03-01 | Buy |
| Cayman Chemical | 16805 | Sulindac sulfone ≥98% | 10mg | $88 | 2024-03-01 | Buy |
| Cayman Chemical | 16805 | Sulindac sulfone ≥98% | 25mg | $173 | 2024-03-01 | Buy |
| Sigma-Aldrich | S1438 | Sulindac sulfone ≥94% (HPLC), (solid or powder) | 5mg | $120 | 2023-06-20 | Buy |
| Sigma-Aldrich | S1438 | Sulindac sulfone ≥94% (HPLC), (solid or powder) | 25mg | $461 | 2024-03-01 | Buy |
| TRC | S699323 | Sulindac sulfone | 100mg | $145 | 2021-12-16 | Buy |
Properties
Melting point :201～203℃
storage temp. :RT
solubility :DMSO: >25 mg/mL
form :solid
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
storage temp. :RT
solubility :DMSO: >25 mg/mL
form :solid
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
Safety Information
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Description
Sulindac is a non-steroidal anti-inflammatory drug that has an extensive epidemiology documenting reduced human colorectal cancer. In mouse models, sulindac was found not only to inhibit the enzymatic activity of polyp-associated COX-2, but also to downregulate the expression of colonic COX-2 protein to control levels. Sulindac sulfone is an oxidized metabolite of sulindac that is produced in many mammals but minimally in mice and rats. It is generally considered to be inactive against COX enzymes, although it can reduce azoxymethane-induced colon cancer in rats. Sulindac sulfone inhibits aldose reductase (IC50 = 367 nM) in vitro and may contribute to the beneficial pharmacological effects of sulindac on type 2 diabetic complications.Related product price
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Suppliers and manufacturers
Hubei Jusheng Technology Co.,Ltd.
TargetMol Chemicals Inc.
Nantong HI-FUTURE Biology Co., Ltd.
China National Standard Pharmaceutical Corporation Limited
Aladdin Scientific
Guangzhou CATO Research Chemicals Inc.
SHANGHAI FORTUNE CHEMICAL TECHNOLOGY CO., LTD
Shanghai Tauto Biotech Co., Ltd.
Guangzhou Isun Pharmaceutical Co., Ltd
Sigma-Aldrich